This paper presents a comprehensive treatment of the parametric sensitivity and runaway in fixed bed reactors with one dimensional pseudo homogeneous dispersion model (ODDM). In this case, we find the existence of m...This paper presents a comprehensive treatment of the parametric sensitivity and runaway in fixed bed reactors with one dimensional pseudo homogeneous dispersion model (ODDM). In this case, we find the existence of multiplicity and determine the runaway criterion through the critical isodisper sion curve. The calculated results indicate when the axial dispersion is relatively small, the impact of the axial dispersion on the parametric sensitivity may be neglected; but when the axial dispersion is large, this impact must be considered.展开更多
This paper applied Maximum Entropy (ME) model to Pinyin-To-Character (PTC) conversion in-stead of Hidden Markov Model (HMM) that could not include complicated and long-distance lexical informa-tion. Two ME models were...This paper applied Maximum Entropy (ME) model to Pinyin-To-Character (PTC) conversion in-stead of Hidden Markov Model (HMM) that could not include complicated and long-distance lexical informa-tion. Two ME models were built based on simple and complex templates respectively, and the complex one gave better conversion result. Furthermore, conversion trigger pair of y A → y B cBwas proposed to extract the long-distance constrain feature from the corpus; and then Average Mutual Information (AMI) was used to se-lect conversion trigger pair features which were added to the ME model. The experiment shows that conver-sion error of the ME with conversion trigger pairs is reduced by 4% on a small training corpus, comparing with HMM smoothed by absolute smoothing.展开更多
In market, excess demands for many products can be met by reorder even during one period, and retailers usually adopt substitution strategy for more benefit. Under the retailer＇s substitution strategy and permission ...In market, excess demands for many products can be met by reorder even during one period, and retailers usually adopt substitution strategy for more benefit. Under the retailer＇s substitution strategy and permission of reorder, we develop the profits maximization model for the two-substitutable-product inventory problem with stochastic demands and proportional costs and revenues. We show that the objective function is concave and submodular, and therefore the optimal policy exists. We present the optimal conditions for order quantity and provide some properties of the optimal order quantities. Comparing our model with Netessine and Rudi＇s, we prove that reorder and adoption of the substitution strategy can raise the general profits and adjust down the general stock level.展开更多
The removal of antibiotics from water by clay minerals has become the focus of research due to their strong adsorptive ability. In this study, adsorption of chlortetracycline (CTC) onto rectories was conducted and the...The removal of antibiotics from water by clay minerals has become the focus of research due to their strong adsorptive ability. In this study, adsorption of chlortetracycline (CTC) onto rectories was conducted and the effects of time, concentration, temperature and pH were investigated. Experimental results showed that adsorption equilibrium was reached in 8 h. Based on the Langmuir model, the maximum adsorption capacity of CTC on rectories was 177.7 mg·g 1 at room temperature. By the study on adsorption dynamics, it is found that the kinetic date fit the pseudo-second-order model well. The adsorption of CTC by rectories is endothermic and the free energy is in the range of 10 to 30 kJ·mol 1 . The pH value of solution has significant effects on adsorption and the optimal pH is at acidity (pH 2-6). At concentration of 2500 mg·L 1 , the intercalated CTC produces an interlayer space with a height of 1.38 nm, which is 1.12 nm in raw rectories, suggesting that the adsorption occurs between layers of rectories.展开更多
Background Haloperidol is the most frequently prescribed antipsycbotic for delirium symptoms. The risk of QTc prolongation often raises concerns, although the effect of haloperidol on QTc interval has not yet been inv...Background Haloperidol is the most frequently prescribed antipsycbotic for delirium symptoms. The risk of QTc prolongation often raises concerns, although the effect of haloperidol on QTc interval has not yet been investigated in a randomised placebo-controlled fixed-dose study. Methods A subanalysis of a randomised double-blind placebo-controlled study was conducted to evaluate the effect of prophylactic haloperidol 1 mg or placebo 1 mg orally twice-daily （maximum of 14 doses） on QTc interval in patients aged 70 years and over. Bedside, 12-lead ECGs were recorded before, during and after the one-week intervention period. Automatic QTc measurements were ob- tained in addition to manual measurements of QT and RR intervals, blinded for treatment status. Manual measurements were corrected （QTc） using Bazett （QTc-B）, Framingham （QTc-Fa）, Fridericia （QTc-Fi） and Hodges （QTc-H） methods. Mixed model analyses were used to test for differences in longitudinal course of QTc between patients receiving haloperidol and placebo. Results ECG recordings of 72 patients （haloperidol n = 38） were analysed, 45.8% male. Median （range） haloperidol serum concentration on day 4 was 0.71 （0.32-1.82） μg/L （n = 23）. Longitudinal course of mean QTc did not significantly differ between treatment arms for any of the automatic or manually derived QTc values. Conclusions Low dose oral haloperidol did not result in QTc prolongation in older acutely hospitalised patients. Results may not be generalizable to patients with existing ECG abnormalities such as atrial fibrillation.展开更多
In this paper, we consider the following semipaxametric regression model under fixed design： yi = xi′β＋g（xi）＋ei. The estimators of β, g（·） and σ^2 axe obtained by using the least squares and usual nonp...In this paper, we consider the following semipaxametric regression model under fixed design： yi = xi′β＋g（xi）＋ei. The estimators of β, g（·） and σ^2 axe obtained by using the least squares and usual nonparametric weight function method and their strong consistency is proved under the suitable conditions.展开更多
Because of its landscape heterogeneity,Koshi Basin（KB） is home to one of the world＇s most abundant,diverse group of species.Habitat change evaluations for key protected species are very important for biodiversity p...Because of its landscape heterogeneity,Koshi Basin（KB） is home to one of the world＇s most abundant,diverse group of species.Habitat change evaluations for key protected species are very important for biodiversity protection in this region.Based on current and future world climate and land cover data,MaxE nt model was used to simulate potential habitat changes for key protected species.The results shows that the overall accuracy of the model is high（AUC 0.9）,suggesting that the MaxE nt-derived distributions are a close approximation of real-world distribution probabilities.The valley around Chentang Town and Dram Town in China,and Lamabagar and the northern part of Landtang National Park in Nepal are the most important regions for the protection of the habitat in KB.The habitat area of Grus nigricollis,Panax pseudoginseng,and Presbytis entellus is expected to decrease in future climate and land cover scenarios.More focus should be placed on protecting forests and wetlands since these are the main habitats for these species.展开更多
This paper discusses a search problem for a Helix target motion in which any information of the target position is not available to the searchers. There exist three searchers start searching for the target from the or...This paper discusses a search problem for a Helix target motion in which any information of the target position is not available to the searchers. There exist three searchers start searching for the target from the origin. The purpose of this paper is to formulate a search model and finds the conditions under which the expected value of the first meeting time between one of the searchers and the target is finite. Also, the existence of the optimal search plan that minimizes the expected value of the first meeting time is shown. Furthermore,this optimal search plan is found. The effectiveness of this method is illustrated by using an example with numerical results.展开更多
We construct a collaborative model of the sparse representation and the subspace representation. First, we represent the tracking target in the principle component analysis(PCA) subspace, and then we employ an L_1 reg...We construct a collaborative model of the sparse representation and the subspace representation. First, we represent the tracking target in the principle component analysis(PCA) subspace, and then we employ an L_1 regularization to restrict the sparsity of the residual term, an L_2 regularization term to restrict the sparsity of the representation coefficients, and an L_2 norm to restrict the distance between the reconstruction and the target. Then we implement the algorithm in the particle filter framework. Furthermore, an iterative method is presented to get the global minimum of the residual and the coefficients. Finally, an alternative template update scheme is adopted to avoid the tracking drift which is caused by the inaccurate update. In the experiment, we test the algorithm on 9 sequences, and compare the results with 5 state-of-art methods. According to the results, we can conclude that our algorithm is more robust than the other methods.展开更多
Based on literature [J. Q. Li, Z. E. Ma and F. Q. Zhang, Stability analysis for an epidemic model with stage structure, J. Appl. Math. Comput. 9 （2008） 1672-1679], incorporating the recovery of the infected populati...Based on literature [J. Q. Li, Z. E. Ma and F. Q. Zhang, Stability analysis for an epidemic model with stage structure, J. Appl. Math. Comput. 9 （2008） 1672-1679], incorporating the recovery of the infected population with the length of the infectious periods, a modified epidemic disease SIS model with delay and stage was investigated. First, the criteria keeping stability with delay were given. Next, in order to lower the level of the infected individuals and minimize the cost of treatment, mixed, early and late therapeutic strategies were introduced into our model, respectively. Then we investigated the existence and uniqueness of optimal controls. And then, we expressed the unique optimal control in terms of the solution of the optimality systems. Finally, by numerical simulations, several important results were acquired： （1） The terminal time influenced the early optimal control largely. In detail, for a shorter terminal time it was optimal to initiate treatment with maximal effort at the start of the epidemic and continue treatment with maximal effort until the switch time was arrived. But for a longer terminal time, the maximal treatment effort need not be a prerequisite at the start or end of the epidemic but it was obligatory at the metaphase of the epidemic. （2） For our SIS model, minimizing the total infectious burden of the disease can be achieved by only early optimal treatment tactics. （3） For a disease with a shorter infectious period time,more cost would be spent to control the disease in order to achieve the optimal control objective. Otherwise, a relative lower cost would be to control the disease with a longer infectious period.展开更多
文摘This paper presents a comprehensive treatment of the parametric sensitivity and runaway in fixed bed reactors with one dimensional pseudo homogeneous dispersion model (ODDM). In this case, we find the existence of multiplicity and determine the runaway criterion through the critical isodisper sion curve. The calculated results indicate when the axial dispersion is relatively small, the impact of the axial dispersion on the parametric sensitivity may be neglected; but when the axial dispersion is large, this impact must be considered.
基金Supported by the National Natural Science Foundation of China as key program (No.60435020) and The HighTechnology Research and Development Programme of China (2002AA117010-09).
文摘This paper applied Maximum Entropy (ME) model to Pinyin-To-Character (PTC) conversion in-stead of Hidden Markov Model (HMM) that could not include complicated and long-distance lexical informa-tion. Two ME models were built based on simple and complex templates respectively, and the complex one gave better conversion result. Furthermore, conversion trigger pair of y A → y B cBwas proposed to extract the long-distance constrain feature from the corpus; and then Average Mutual Information (AMI) was used to se-lect conversion trigger pair features which were added to the ME model. The experiment shows that conver-sion error of the ME with conversion trigger pairs is reduced by 4% on a small training corpus, comparing with HMM smoothed by absolute smoothing.
文摘In market, excess demands for many products can be met by reorder even during one period, and retailers usually adopt substitution strategy for more benefit. Under the retailer＇s substitution strategy and permission of reorder, we develop the profits maximization model for the two-substitutable-product inventory problem with stochastic demands and proportional costs and revenues. We show that the objective function is concave and submodular, and therefore the optimal policy exists. We present the optimal conditions for order quantity and provide some properties of the optimal order quantities. Comparing our model with Netessine and Rudi＇s, we prove that reorder and adoption of the substitution strategy can raise the general profits and adjust down the general stock level.
基金Supported by the Fundamental Research Funds for the Central Universities (2011YXL056)the National Program of Control and Treatment of Water Pollution (2009ZX07424-002)
文摘The removal of antibiotics from water by clay minerals has become the focus of research due to their strong adsorptive ability. In this study, adsorption of chlortetracycline (CTC) onto rectories was conducted and the effects of time, concentration, temperature and pH were investigated. Experimental results showed that adsorption equilibrium was reached in 8 h. Based on the Langmuir model, the maximum adsorption capacity of CTC on rectories was 177.7 mg·g 1 at room temperature. By the study on adsorption dynamics, it is found that the kinetic date fit the pseudo-second-order model well. The adsorption of CTC by rectories is endothermic and the free energy is in the range of 10 to 30 kJ·mol 1 . The pH value of solution has significant effects on adsorption and the optimal pH is at acidity (pH 2-6). At concentration of 2500 mg·L 1 , the intercalated CTC produces an interlayer space with a height of 1.38 nm, which is 1.12 nm in raw rectories, suggesting that the adsorption occurs between layers of rectories.
文摘Background Haloperidol is the most frequently prescribed antipsycbotic for delirium symptoms. The risk of QTc prolongation often raises concerns, although the effect of haloperidol on QTc interval has not yet been investigated in a randomised placebo-controlled fixed-dose study. Methods A subanalysis of a randomised double-blind placebo-controlled study was conducted to evaluate the effect of prophylactic haloperidol 1 mg or placebo 1 mg orally twice-daily （maximum of 14 doses） on QTc interval in patients aged 70 years and over. Bedside, 12-lead ECGs were recorded before, during and after the one-week intervention period. Automatic QTc measurements were ob- tained in addition to manual measurements of QT and RR intervals, blinded for treatment status. Manual measurements were corrected （QTc） using Bazett （QTc-B）, Framingham （QTc-Fa）, Fridericia （QTc-Fi） and Hodges （QTc-H） methods. Mixed model analyses were used to test for differences in longitudinal course of QTc between patients receiving haloperidol and placebo. Results ECG recordings of 72 patients （haloperidol n = 38） were analysed, 45.8% male. Median （range） haloperidol serum concentration on day 4 was 0.71 （0.32-1.82） μg/L （n = 23）. Longitudinal course of mean QTc did not significantly differ between treatment arms for any of the automatic or manually derived QTc values. Conclusions Low dose oral haloperidol did not result in QTc prolongation in older acutely hospitalised patients. Results may not be generalizable to patients with existing ECG abnormalities such as atrial fibrillation.
基金Supported by the National Natural Science Foundation of China(10571008)Supported by the Natural Science Foundation of Henan(0511013300)Supported by the National Science Foundation of Henan Education Department(2006110012)
文摘In this paper, we consider the following semipaxametric regression model under fixed design： yi = xi′β＋g（xi）＋ei. The estimators of β, g（·） and σ^2 axe obtained by using the least squares and usual nonparametric weight function method and their strong consistency is proved under the suitable conditions.
基金National Natural Science Foundation of China(41371120)Tibet Key Science and Technology Program(2015XZ01G72)The Australian Government-funded Koshi Basin Programme at the International Centre for Integrated Mountain Development(ICIMOD)
文摘Because of its landscape heterogeneity,Koshi Basin（KB） is home to one of the world＇s most abundant,diverse group of species.Habitat change evaluations for key protected species are very important for biodiversity protection in this region.Based on current and future world climate and land cover data,MaxE nt model was used to simulate potential habitat changes for key protected species.The results shows that the overall accuracy of the model is high（AUC 0.9）,suggesting that the MaxE nt-derived distributions are a close approximation of real-world distribution probabilities.The valley around Chentang Town and Dram Town in China,and Lamabagar and the northern part of Landtang National Park in Nepal are the most important regions for the protection of the habitat in KB.The habitat area of Grus nigricollis,Panax pseudoginseng,and Presbytis entellus is expected to decrease in future climate and land cover scenarios.More focus should be placed on protecting forests and wetlands since these are the main habitats for these species.
文摘This paper discusses a search problem for a Helix target motion in which any information of the target position is not available to the searchers. There exist three searchers start searching for the target from the origin. The purpose of this paper is to formulate a search model and finds the conditions under which the expected value of the first meeting time between one of the searchers and the target is finite. Also, the existence of the optimal search plan that minimizes the expected value of the first meeting time is shown. Furthermore,this optimal search plan is found. The effectiveness of this method is illustrated by using an example with numerical results.
基金supported by the National Natural Science Foundation of China(No.61401425)
文摘We construct a collaborative model of the sparse representation and the subspace representation. First, we represent the tracking target in the principle component analysis(PCA) subspace, and then we employ an L_1 regularization to restrict the sparsity of the residual term, an L_2 regularization term to restrict the sparsity of the representation coefficients, and an L_2 norm to restrict the distance between the reconstruction and the target. Then we implement the algorithm in the particle filter framework. Furthermore, an iterative method is presented to get the global minimum of the residual and the coefficients. Finally, an alternative template update scheme is adopted to avoid the tracking drift which is caused by the inaccurate update. In the experiment, we test the algorithm on 9 sequences, and compare the results with 5 state-of-art methods. According to the results, we can conclude that our algorithm is more robust than the other methods.
基金Acknowledgments The authors would like to thank the editor and the referee for constructive comments which significantly improves this paper. In addition, this work was supported by the National Natural Science Foundation of China （No. 11471243）.
文摘Based on literature [J. Q. Li, Z. E. Ma and F. Q. Zhang, Stability analysis for an epidemic model with stage structure, J. Appl. Math. Comput. 9 （2008） 1672-1679], incorporating the recovery of the infected population with the length of the infectious periods, a modified epidemic disease SIS model with delay and stage was investigated. First, the criteria keeping stability with delay were given. Next, in order to lower the level of the infected individuals and minimize the cost of treatment, mixed, early and late therapeutic strategies were introduced into our model, respectively. Then we investigated the existence and uniqueness of optimal controls. And then, we expressed the unique optimal control in terms of the solution of the optimality systems. Finally, by numerical simulations, several important results were acquired： （1） The terminal time influenced the early optimal control largely. In detail, for a shorter terminal time it was optimal to initiate treatment with maximal effort at the start of the epidemic and continue treatment with maximal effort until the switch time was arrived. But for a longer terminal time, the maximal treatment effort need not be a prerequisite at the start or end of the epidemic but it was obligatory at the metaphase of the epidemic. （2） For our SIS model, minimizing the total infectious burden of the disease can be achieved by only early optimal treatment tactics. （3） For a disease with a shorter infectious period time,more cost would be spent to control the disease in order to achieve the optimal control objective. Otherwise, a relative lower cost would be to control the disease with a longer infectious period.
