Background. Patients with Turner’ s syndrome receiving unopposed estrogens for the induction of feminization have an increased risk of endometrial carcinoma. Only seven patients who were not treated with estrogen rep...Background. Patients with Turner’ s syndrome receiving unopposed estrogens for the induction of feminization have an increased risk of endometrial carcinoma. Only seven patients who were not treated with estrogen replacement therapy have been reported to have developed endometrial carcinoma at different age levels. Case. A young girl with Turner’ s syndrome phenotype, spontaneous puberty, and karyotype 45,X0/47,XXX from peripheral blood, after irregular menstrual cycles of 9 years, at the age of 21, was diagnosed with a non- invasive welldifferentiated endometrial carcinoma confined to a hyperplastic endometrial polyp. Analysis of the ovarian tissue by FISH confirmed mosaicism: 45,X0/46,XX/47,XXX. Conclusion(s)- . The endogenous estrogen secretion from the ovaries might have caused malignancy in this case. Patients with Turner’ s syndrome with spontaneous menarche might carry a higher risk of endometrial carcinoma.展开更多
患者女,24岁,孕2产1,既往史无特殊。因＂停经40 d,下腹坠痛半天,晕厥一次＂入院,停经后无阴道出血及恶心呕吐,入院前半天无明显诱因出现下腹坠痛,伴头晕、乏力晕厥一次。曾于外院超声检查未见妊囊,盆腔积液,平素月经规则,量中等,色暗红...患者女,24岁,孕2产1,既往史无特殊。因＂停经40 d,下腹坠痛半天,晕厥一次＂入院,停经后无阴道出血及恶心呕吐,入院前半天无明显诱因出现下腹坠痛,伴头晕、乏力晕厥一次。曾于外院超声检查未见妊囊,盆腔积液,平素月经规则,量中等,色暗红,无痛经。血压：90/60 mm Hg（1 mm Hg=0.133 k Pa）。患者面色苍白,心肺（-）,腹肌紧张,下腹压痛（＋）,反跳痛（＋）。展开更多
一、病历摘要患者39岁,因＂停经45天,发现切口妊娠1周＂于2014年10月19日入院。平时月经规则,4~5/26~27天,量少,无痛经,LMP：2014年9月4日,停经37天自测尿妊娠试验（＋）,1周前医院B超检查示：瘢痕妊娠,考虑子宫下段近峡部妊娠就诊我院...一、病历摘要患者39岁,因＂停经45天,发现切口妊娠1周＂于2014年10月19日入院。平时月经规则,4~5/26~27天,量少,无痛经,LMP：2014年9月4日,停经37天自测尿妊娠试验（＋）,1周前医院B超检查示：瘢痕妊娠,考虑子宫下段近峡部妊娠就诊我院,病程中无恶心呕吐等早孕反应,无肛门坠胀感,2004年行剖宫产手术。入院时查体：体温：36.8℃,呼吸：20次/分,心率：96次/分,血压：108/86 mm Hg。妇科检查：外阴：婚产式,阴道：通畅,宫颈：中糜,宫体：后位,如孕50天大小,无压痛,附件：（-）。展开更多
文摘Background. Patients with Turner’ s syndrome receiving unopposed estrogens for the induction of feminization have an increased risk of endometrial carcinoma. Only seven patients who were not treated with estrogen replacement therapy have been reported to have developed endometrial carcinoma at different age levels. Case. A young girl with Turner’ s syndrome phenotype, spontaneous puberty, and karyotype 45,X0/47,XXX from peripheral blood, after irregular menstrual cycles of 9 years, at the age of 21, was diagnosed with a non- invasive welldifferentiated endometrial carcinoma confined to a hyperplastic endometrial polyp. Analysis of the ovarian tissue by FISH confirmed mosaicism: 45,X0/46,XX/47,XXX. Conclusion(s)- . The endogenous estrogen secretion from the ovaries might have caused malignancy in this case. Patients with Turner’ s syndrome with spontaneous menarche might carry a higher risk of endometrial carcinoma.
文摘患者女,24岁,孕2产1,既往史无特殊。因＂停经40 d,下腹坠痛半天,晕厥一次＂入院,停经后无阴道出血及恶心呕吐,入院前半天无明显诱因出现下腹坠痛,伴头晕、乏力晕厥一次。曾于外院超声检查未见妊囊,盆腔积液,平素月经规则,量中等,色暗红,无痛经。血压：90/60 mm Hg（1 mm Hg=0.133 k Pa）。患者面色苍白,心肺（-）,腹肌紧张,下腹压痛（＋）,反跳痛（＋）。
文摘一、病历摘要患者39岁,因＂停经45天,发现切口妊娠1周＂于2014年10月19日入院。平时月经规则,4~5/26~27天,量少,无痛经,LMP：2014年9月4日,停经37天自测尿妊娠试验（＋）,1周前医院B超检查示：瘢痕妊娠,考虑子宫下段近峡部妊娠就诊我院,病程中无恶心呕吐等早孕反应,无肛门坠胀感,2004年行剖宫产手术。入院时查体：体温：36.8℃,呼吸：20次/分,心率：96次/分,血压：108/86 mm Hg。妇科检查：外阴：婚产式,阴道：通畅,宫颈：中糜,宫体：后位,如孕50天大小,无压痛,附件：（-）。
