加味解痉祛风汤治疗支气管哮喘慢性持续期风哮证临床研究

目的探讨加味解痉祛风汤治疗支气管哮喘慢性持续期风哮证的临床疗效。方法 76例支气管哮喘慢性持续期风哮证患者,随机分为观察组和对照组,各38例。对照组采用沙美特罗替卡松治疗,观察组在对照组基础上联合加味解痉祛风汤治疗,两组患者均治疗1个疗程后,比较两组治疗效果及中医证候积分。结果治疗后,观察组总有效率为97.37%,高于对照组的73.68%,差异有统计学意义(P<0.05)。两组患者治疗后中医证候积分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。结论加味解痉祛风汤治疗支气管哮喘慢性持续期风哮证临床疗效佳,患者中医证候积分显著改善,值得临床推广。

平喘方加减配合布地奈德混悬液雾化吸入治疗小儿哮喘发作期风痰哮证的价值分析

目的:研究平喘方加减配合布地奈德混悬液雾化吸入治疗小儿哮喘发作期风痰哮证的价值。方法:选择2017年10月-2018年10月在笔者所在医院临床治疗的200例哮喘发作期风痰哮证患儿作为本次研究对象,根据其入院顺序分为两组,先入院的100例为对照组,后入院的100例为观察组。观察组实施平喘方加减配合布地奈德混悬液雾化吸入治疗,对照组实施布地奈德混悬液雾化吸入单一治疗,对比两组治疗效果。结果:观察组治疗总有效率高于对照组,差异有统计学意义(χ^2=17.543,P<0.05)。观察组咳嗽、喘息、呼吸困难、哮鸣音消失时间均早于对照组,差异均有统计学意义(t=12.639、18.845、14.066、17.798,P<0.05)。观察组治疗后FVC、FEV1、PEFR水平均高于对照组,差异有统计学意义(t=16.364、13.842、17.381,P<0.05)。观察组不良反应发生率低于对照组,差异有统计学意义(χ^2=25.149,P<0.05)。结论:小儿哮喘发作期风痰哮证采用联合治疗方式,相比单一治疗更具有优势,且安全性高,对改善患儿肺功能指标和早期改善患儿临床症状均具有重大意义,值得研究和推广。

风电场运行期噪声影响范围及防治措施

本文分析风电场运行期噪声影响范围和防治措施,为新建项目环境影响评价、设计、选址提供依据,避免建成后带来环境问题;提出已建项目噪声范围确定原则和治理措施。

化痰通络汤联合针刺治疗脑梗死急性期风痰瘀阻证疗效观察

目的研究分析化痰通络汤联合针刺治疗脑梗死急性期风痰瘀阻证疗效观察。方法选取该院2015年1月—2017年1月收治的60例脑梗死急性期风痰瘀阻证患者,随机(抽签、就诊序号等方法)将60例患者分为两组(实验组、对照组,n=30)。对照组进行常规西医治疗,实验组进行化痰通络汤联合针刺治疗。两组患者治疗时间均为14 d,比较分析两组患者临床效果及NIHSS评分情况。结果经过对应的治疗后,实验组NIHSS评分为(6.25±4.20)分显著低于对照组评分为(11.21±4.72)分,差异有统计学意义(P<0.05)。实验组中,1例恶化,2例无变化。对照组中,3例恶化,6例无变化。可得,实验组治疗有效率为90.0%显著高于对照组有效率(70.0%),差异有统计学意义(P<0.05)。结论化痰通络汤联合针刺治疗脑梗死急性期风痰瘀阻证疗效较为理想,能够显著改善患者临床症状,帮助患者恢复,具有推广的意义。

真方白丸子汤治疗缺血性中风急性期风痰入络型患者的临床疗效

缺血性中风急性期采用何种药物治疗效果显著一直是临床研究的重点问题,本文主要对风痰入络型患者应用真方白丸子汤的治疗效果进行探究。方法:将入我院治疗缺血性中风急性期的患者进行研究,且中医分型为风痰入络型,共计选取90例(2018.1-2020.6),因患者给予治疗手段的差异性可患者分为二组,将其中45例采用常规治疗的患者作为对照组,其他45例患者采用常规+真方白丸子汤治疗,探究二组患者的疗效。本次关于真方白丸子汤治疗缺血性中风急性期风痰入络型患者的临床疗效研究的观察指标为:对比二组患者疗效、神经功能缺损评分、中医症候积分、住院时间、费用。疗效:显效:缺血性中风患者的临床症状改善极为明显,生活可完全自理,肌力得到有效恢复;有效:缺血性中风患者的症状有所缓解,患者日常生活部分可自理;无效:缺血性中风患者症状依然存在,生活无法自理,肌力评级较差。缺血性中风判断标准为NIHSS量表,得分越高,患者的神经功能缺损越严重;中医症候积分判断:一侧肢体麻木、语言障碍、眩晕症状,无症状、轻度、中度、重度分别记0分、1分、2分、3分。结果:本次关于真方白丸子汤治疗缺血性中风急性期风痰入络型患者的临床疗效研究的研究结果为:二组患者的疗效对比,存在显著性差异(P<0.05);对二组患者治疗前后神经功能缺损评分、中医症候积分进行统计计算,治疗前,无统计学意义(P>0.05);治疗后,实验组各数据优势较为明显(P<0.05);完成二组患者的住院时间、费用对比,有统计学意义(P<0.05)。结论:缺血性中风急性期风痰入络型患者应采用真方白丸子汤治疗,效果确切,值得推广。

化痰通络汤联合针刺治疗脑梗死急性期风痰瘀阻证疗效观察

分析化痰通络汤联合针刺治疗脑梗死急性期风痰瘀阻证的临床疗效。方法:将2019年5月~2021年9月新疆伊犁州中医医院诊治的55例脑梗死急性期风痰瘀阻证患者按照其治疗方式的不同分为研究组(30例,采用化痰通络汤联合针刺治疗)和参考组(25例,采用常规西药治疗),对比分析两组疗效。结果:研究组治疗总有效率、生活质量评分改善与参考组相比差异具有统计学意义(P<0.05),不良反应发生率比较差异不具统计学意义(P>0.05)。结论:化痰通络汤联合针刺治疗脑梗死急性期风痰瘀阻证具有良好的临床效果,且不会增加不良反应,是一种安全有效的治疗方式。

中医护理方案在脑梗死急性期后风痰上扰证眩晕护理中的应用研究

研究中医护理方案在脑梗死急性期后风痰上扰证眩晕护理中的应用研究。方法 试验时段是2020年12月份到2022年12月份,在这段时间内,我院接诊的被证实为脑梗死急性期后,风痰上扰证头晕的患者有460名,将其以客观的方式,将其客观性地平均成了对照组与试验组,各有230名。其中,对照组采用的是一般常规护理模式,试验组采用的是中医护理模式。对比两组在护理干预后的生活质量、心理状态、护理依从性和护理满意度的提高情况。结果 比较实验组与对照组比较差异。结论 探讨中药治疗脑梗塞后头晕风痰湿症的方法及疗效。提升护理依从性,让患者更加配合治疗,具有较高的临床应用前景。

Pricing Catastrophe Options with Credit Risk in a Regime-Switching Model

In this paper,we consider the price of catastrophe options with credit risk in a regime-switching model.We assume that the macroeconomic states are described by a continuous-time Markov chain with a finite state space.By using the measure change technique,we derive the price expressions of catastrophe put options.Moreover,we conduct some numerical analysis to demonstrate how the parameters of the model affect the price of the catastrophe put option.

Research on Optimization of Component Stock

A set of model is established to optimize BSW Company’s component stock. By analyzing the company’s current part stock condition in terms of the occupation of capitals in the precondition of continuous production, it describes how to control the purchase parameters of import parts. The model describes how to adjust slightly product output sequence and how to control the components’ purchase parameters: purchasing risk time and purchase order quantity. Then simulation is developed to illustrate the model.

Risk assessment of lead emissions from anthropogenic cycle

The risk assessment right from the source of emissions can effectively guide the pollution control. A model was established, consisting of four part： source estimation, environmental fate analysis, exposure analysis and risk assessment. The human health risk, ecological risk and total risk of lead emissions were assessed. The factors were estimated to indicate the environmental decrease and exposure probability. Of all the 1887 t emissions in China in 2010（quantified in the previous work）, it is turned out 1.3 t reached human bodies（0.9 mg/ca）, and 2.7 t reached the ecosystem. Lead mainly came from the Use stage for the source while lead causing risk mainly came from the Waste Management Recycling and Production stages. As for chemical forms, PbO contributed most to the human health risk and PbSO_4 contributed most to the ecological risk. PbSO_4, PbO and Pb altogether contributed 71% to the total risk, indicating these three chemicals should be taken priority for the risk management.

China’s Economy in the Advanced Stage of Industrialization:Tendencies and Risks

In 2010, China entered the advanced stage of industrialization, which coincided with the country＇s entry into a new stage of economic growth. However, this transition is associated with major risks, including adapting to decelerating economic growth. While recognizing the move toward a service-based economy, China must seek to prevent the risk of ＂manufacturing hollowing out. ＂＇ It must also avoid the ＂technology upgrade trap＂ while taking advantage of increasingly sophisticated industrial structures. Efforts must also be made to： （1） promote the integration of lT tools and meet risks arising from the New Industrial Revolution; （2） resolve liability risks arising from capacity reduction; and （3） expedite the transition to a functional industrial policy and prevent the failure of a functional industrial policy. In climbing up the global value chain, China must confront the competitive pressures from advanced and emerging economies on both high- and low-end processes of the global value chain.

Recovering implied risk-neutral probability density function using SVR

Using support vector regression （SVR）, a novel non-parametric method for recovering implied risk-neutral probability density function （IRNPDF） is investigated by solving linear operator equations. First, the SVR principle for function approximation is introduced, and an SVR method for solving linear operator equations with knowing some values of the right-hand function and without knowing its form is depicted. Then, the principle for solving the IRNPDF based on SVR and the method for constructing cross-kernel functions are proposed. Finally, an empirical example is given to verify the validity of the method. The results show that the proposed method can overcome the shortcomings of the traditional parametric methods, which have strict restrictions on the option exercise price; meanwhile, it requires less data than other non-parametric methods, and it is a promising method for the recover of IRNPDF.

Risk factors for predicting early variceal rebleeding after endoscopic variceal ligation

AIM: To analyze the clinical risk factors for early variceal rebleeding after endoscopic variceal ligation (EVL).METHODS: 342 cirrhotic patients with esophageal varices who received elective EVL to prevent bleeding or rebleeding at our endoscopy center between January 2005 and July 2010.were included in this study.The early rebleeding cases after EVL were confirmed by clinical signs or endoscopy.A case-control study was performed comparing the patients presenting with early rebleeding with those without this complication.RESULTS: The incidence of early rebleeding after EVL was 7.60%,and the morbidity of rebleeding was 26.9%.Stepwise multivariate logistic regression analysis showed that four variables were independent risk factors for early rebleeding: moderate to excessive ascites [odds ratio (OR) 62.83,95% CI: 9.39-420.56,P < 0.001],the number of bands placed (OR 17.36,95% CI: 4.00-75.34,P < 0.001),the extent of varices (OR 15.41,95% CI: 2.84-83.52,P = 0.002) and prothrombin time (PT) > 18 s (OR 11.35,95% CI: 1.93-66.70,P = 0.007).CONCLUSION: The early rebleeding rate after EVL is mainly affected by the volume of ascites,number of rubber bands used to ligate,severity of varices and prolonged PT.Effective measures for prevention and treatment should be adopted before and after EVL.

The Survival Probability in Generalized Poisson Risk Model

In this paper we generalize the aggregated premium income process from a constant rate process to a poisson process for the classical compound Poinsson risk model,then for the generalized model and the classical compound poisson risk model ,we respectively get its survival probability in finite time period in case of exponential claim amounts.

Assemblage characteristics of clay minerals and its implications to evolution of eolian dust input to the Parece Vela Basin since 1.95 Ma

To understand the provenance and evolution of eolian input in the last 1.95 Ma in the Parece Vela Basin in the eastern Philippine Sea, the clay mineral assemblage of a gravity core PV090510 from the basin was investigated using paleogeomagnetic dating and X-ray diffraction. The assemblage of the core mainly consisted of smectite （-46%） and illite （-40%）, with some chlorite （-10%） and kaolinite （-4%）. Analysis of the provenance of these minerals suggested that smectite was mainly derived from volcanic rocks of the Mariana Arc, while illite, chlorite, and kaolinite were mainly transported as eolian dust by the East Asian monsoon from central Asia. We used the ratio of （illite＋chlorite＋kaolinite）/smectite as a proxy for Asian eolian input to the Parece Vela Basin since 1.95 Ma. This ratio followed glacial and interglacial cycles and was consistent with the intensity of the East Asian monsoon and aridity of central Asia since 1.95 Ma. The changes of the ratio reflected three different stages of the East Asian monsoon and provenance climate.

Molecular biology of pancreatic cancer

In spite of continuous research efforts directed at early detection and treatment of pancreatic cancer, the outlook for patients affected by the disease remains dismal. With most cases still being diagnosed at advanced stages, no improvement in survival prognosis is achieved with current diagnostic imaging approaches. In the absence of a dominant precancerous condition, several risk factors have been identified including family history, chronic pancreatitis, smoking, diabetes mellitus, as well as certain genetic disorders such as hereditary pancreatitis, cystic fibrosis, familial atypical multiple mole melanoma, and Peutz-Jeghers and Lynch syn- dromes. Most pancreatic carcinomas, however, remain sporadic. Current progress in experimental molecular techniques has enabled detailed understanding of the molecular processes of pancreatic cancer development. According to the latest information, malignant pancre- atic transformation involves multiple oncogenes and tumor-suppressor genes that are involved in a variety of signaling pathways. The most characteristic aberrations （somatic point mutations and allelic losses） affect onco- genes and tumor-suppressor genes within RAS, AK-I- and Wnt signaling, and have a key role in transcription and proliferation, as well as systems that regulate the cell cycle （SMAD/DPC, CDKN2A/p16） and apoptosis （TP53）. Understanding of the underlying molecular mechanisms should promote development of new methodology for early diagnosis and facilitate improvement in current approaches for pancreatic cancer treatment.

Short-Term Wind Power Prediction Using Fuzzy Clustering and Support Vector Regression

A sustainable production of electricity is essential for low carbon green growth in South Korea. The generation of wind power as renewable energy has been rapidly growing around the world. Undoubtedly, wind energy is unlimited in potential. However due to its own intermittency and volatility, there are difficulties in the effective harvesting of wind energy and the integration of wind power into the current electric power grid. To cope with this, many works have been done for wind speed and power forecasting. In this paper, an SVR （support vector regression） using FCM （Fuzzy C-Means） is proposed for wind speed forecasting. This paper describes the design of an FCM based SVR to increase the prediction accuracy. Proposed model was compared with ordinary SVR model using balanced and unbalanced test data. Also, multi-step ahead forecasting result was compared. Kernel parameters in SVR are adaptively determined in order to improve forecasting accuracy. An illustrative example is given by using real-world wind farm dataset. According to the experimental results, it is shown that the proposed method provides better forecasts of wind power.

Empirical study on mutual fund objective classification

Mutual funds are usually classified on the basis of their objectives. If the activities of mutual funds are consistent with their stated objectives, investors may look at the latter as signals of their risks and incomes. This work analyzes mutual fund objective classification in China by statistical methods of distance analysis and discriminant analysis; and examines whether the stated investment objectives of mutual funds adequately represent their attributes to investors. That is, if mutual funds adhere to their stated objectives, attributes must be heterogeneous between investment objective groups and homogeneous within them. Our conclusion is to some degree, the group of optimized exponential funds is heterogeneous to other groups. As a whole, there exist no significant differences between different objective groups; and 50% of mutual funds are not consistent with their objective groups.

Major Mid-Late Holocene Cooling in the East China Sea Revealed by an Alkenone Sea Surface Temperature Record

Although the mid-late Holocene cold and dry event about 4000years ago （the 4ka event） has been observed almost globally, it was most prominent in terrestrial climate proxies from the lower latitudes. Here we evaluate the oceanic response to this event in terms of a Holocene sea surface temperature （SST） record reconstructed using the U^7 index for Core B3 on the continen- tal shelf of the East China Sea. The record reveals a large temperature drop of about 5~C from the mid-Holocene （24.7~C at 5.6ka） to the 4ka event （19.2~C at 3.8ka）. This mid-late Holocene cooling period in Core B3 correlated with （i） decreases in the East Asia summer monsoon intensity and （ii） the transition period with increased E1 Nifio/Southern Oscillation activities in the Equatorial Pa- cific. Our SST record provides oceanic evidence for a more global nature of the mid-late Holocene climate change, which was most likely caused by a southward migration of the Intertropical Converge Zone in response to the decreasing summer solar insolation in the Northern Hemisphere. However, the large SST drop around Core B3 indicates that the mid-late Holocene cooling was regionally amplified by the initiation/strengthening of eddy circulation/cold front which caused upwelling and resulted in additional SST de- crease. Upwelling during the mid-late Holocene also enhanced with surface productivity in the East China Sea as reflected by higher alkenone content around Core B3.

An East Asian Monsoon in the Mid-Pliocene

In this study, the authors simulate the East Asian climate changes in the mid-Pliocene (～3.3 to 3.0 Ma BP) with the Community Atmosphere Model version 3.1 (CAM3.1) and compare the simulated East Asian monsoon with paleoclimate data. The simulations show an obvious warming pattern in East Asia in the mid-Pliocene compared with the pre-industrial climate, with surface air temperature increasing by 0.5 4.0°C. In the warm mid-Pliocene simulation, the East Asian Summer Monsoon (EASM) becomes stronger, while the East Asian Winter Monsoon (EAWM) is similar relative to the pre-industrial climate. Compared with the paleoclimate data, our simulations depict the intensified EASM well but cannot reproduce the weakened EAWM. This model-data discrepancy may be attributed to the uncertainty in the reconstructed mid-Pliocene sea surface temperature.