Starting with a simple presentation of location determination techniques, physical location and geographic location as two common kinds of location description methods are discussed. The semantic location concept is t...Starting with a simple presentation of location determination techniques, physical location and geographic location as two common kinds of location description methods are discussed. The semantic location concept is then introduced and a correction is given, which especially emphasizes that location property is an important part of semantic location. By analyzing the connotation and extension of every geographic location, what should be contained in a location property is determined. Using a hierarchical model, the relations and associations among locations are clearly described. To realize a formalized description of semantic location, an ontology technique that can adequately describe semantic information of location is used. Organized by ontology web language, a location ontology model allows semantic location to be read and processed by computer. The location ontology model realizes the knowledge description of location information and establishes an important foundation to personalized preference services in location based services.展开更多
Based on Martin Buber＇s theory of ＂Ontology of Between＂, the present paper tries to analyze the unfathomable themes in Wise Blood and argues that the world of Wise Blood （1968） is a highly commercialized society ...Based on Martin Buber＇s theory of ＂Ontology of Between＂, the present paper tries to analyze the unfathomable themes in Wise Blood and argues that the world of Wise Blood （1968） is a highly commercialized society filled with spiritual blindness, moral degeneration, and social corruption. In keeping with O＇Conner＇s artistic creations, the more disgusting the It-world in Wise Blood is represented to the readers, the more palpable her implication becomes that such a world needs the necessary and urgent spiritual redemption.展开更多
The present article focuses on Heidegger＇s productive appropriation of Aristotle＇s rhetoric. It pays special attention to the lectures of 1924, Basic Concepts of.4ristotelian Philosophy, and its later influence on t...The present article focuses on Heidegger＇s productive appropriation of Aristotle＇s rhetoric. It pays special attention to the lectures of 1924, Basic Concepts of.4ristotelian Philosophy, and its later influence on the phenomenon of idle talk exposed in Being and Time. First, a brief overview is given of Heidegger＇s early rediscovery of Aristotle＇s political and practical writings. Second, special attention is given to his ontological reading of Aristotle＇s practical and political writings, focusing on the sphere of communicability and publicness inherent to opinions. And third, the paper describes the positive and negative aspects related to the phenomenon of idle talk sketched out in Being and Time, a phenomenon which condensates a good portion of his early interpretations of Aristotelian rhetoric.展开更多
Objective:To explore the pharmacological action mechanism of Fang Ji Huang Qi decoction(FHD)in the treatment of rheumatoid arthritis(RA)by network pharmacology.Methods:The chemical compositions and functional targets ...Objective:To explore the pharmacological action mechanism of Fang Ji Huang Qi decoction(FHD)in the treatment of rheumatoid arthritis(RA)by network pharmacology.Methods:The chemical compositions and functional targets of the TCM were retrieved using the systematic pharmacological analysis platform TCMSP,and the gene name of each target protein was obtained from the UniProtKB network platform.The targets of RA were queried through the CTD database.The protein–protein interaction network was constructed in the STRING database,and the network visualization analysis was performed in Cytoscape.The Gene Ontology and Kyoto Gene and Genomic Encyclopedia pathways enrichment analyses of key target proteins were performed using the DAVID data platform.Results:A total of 472 drug active ingredients were screened from the TCMSP database.Seventy-five disease targets from the CTD database were screened.The compound-target network map contained further screened out 98 components and corresponding 75 targets.The key compounds included quercetin and kaempferol.The key targets were prostaglandin G/H synthase 2 and nitric oxide synthase 2.The protein-protein interaction network consisted of 75 proteins,of which 37 were key proteins,including tumor protein 53,JUN and interleukin-6.There were 260 Gene Ontology entries,of which 246 were biological processes.Fifty-five Kyoto Gene and Genomic Encyclopedia pathways were enriched,mainly the cancer pathway,NOD-like receptor signaling pathway,and Toll-like receptor signaling pathway,which are involved in the action mechanism of FHD.Conclusion:The results of this study preliminarily verified the basic pharmacological action mechanism of FHD in the treatment of RA,laying a foundation for elucidating its mechanism of action.展开更多
基金Supported by the Open Research Fund Program of the Geomatics and Applications Laboratory, Liaoning Technical University (No. 2005001).
文摘Starting with a simple presentation of location determination techniques, physical location and geographic location as two common kinds of location description methods are discussed. The semantic location concept is then introduced and a correction is given, which especially emphasizes that location property is an important part of semantic location. By analyzing the connotation and extension of every geographic location, what should be contained in a location property is determined. Using a hierarchical model, the relations and associations among locations are clearly described. To realize a formalized description of semantic location, an ontology technique that can adequately describe semantic information of location is used. Organized by ontology web language, a location ontology model allows semantic location to be read and processed by computer. The location ontology model realizes the knowledge description of location information and establishes an important foundation to personalized preference services in location based services.
文摘Based on Martin Buber＇s theory of ＂Ontology of Between＂, the present paper tries to analyze the unfathomable themes in Wise Blood and argues that the world of Wise Blood （1968） is a highly commercialized society filled with spiritual blindness, moral degeneration, and social corruption. In keeping with O＇Conner＇s artistic creations, the more disgusting the It-world in Wise Blood is represented to the readers, the more palpable her implication becomes that such a world needs the necessary and urgent spiritual redemption.
文摘The present article focuses on Heidegger＇s productive appropriation of Aristotle＇s rhetoric. It pays special attention to the lectures of 1924, Basic Concepts of.4ristotelian Philosophy, and its later influence on the phenomenon of idle talk exposed in Being and Time. First, a brief overview is given of Heidegger＇s early rediscovery of Aristotle＇s political and practical writings. Second, special attention is given to his ontological reading of Aristotle＇s practical and political writings, focusing on the sphere of communicability and publicness inherent to opinions. And third, the paper describes the positive and negative aspects related to the phenomenon of idle talk sketched out in Being and Time, a phenomenon which condensates a good portion of his early interpretations of Aristotelian rhetoric.
文摘Objective:To explore the pharmacological action mechanism of Fang Ji Huang Qi decoction(FHD)in the treatment of rheumatoid arthritis(RA)by network pharmacology.Methods:The chemical compositions and functional targets of the TCM were retrieved using the systematic pharmacological analysis platform TCMSP,and the gene name of each target protein was obtained from the UniProtKB network platform.The targets of RA were queried through the CTD database.The protein–protein interaction network was constructed in the STRING database,and the network visualization analysis was performed in Cytoscape.The Gene Ontology and Kyoto Gene and Genomic Encyclopedia pathways enrichment analyses of key target proteins were performed using the DAVID data platform.Results:A total of 472 drug active ingredients were screened from the TCMSP database.Seventy-five disease targets from the CTD database were screened.The compound-target network map contained further screened out 98 components and corresponding 75 targets.The key compounds included quercetin and kaempferol.The key targets were prostaglandin G/H synthase 2 and nitric oxide synthase 2.The protein-protein interaction network consisted of 75 proteins,of which 37 were key proteins,including tumor protein 53,JUN and interleukin-6.There were 260 Gene Ontology entries,of which 246 were biological processes.Fifty-five Kyoto Gene and Genomic Encyclopedia pathways were enriched,mainly the cancer pathway,NOD-like receptor signaling pathway,and Toll-like receptor signaling pathway,which are involved in the action mechanism of FHD.Conclusion:The results of this study preliminarily verified the basic pharmacological action mechanism of FHD in the treatment of RA,laying a foundation for elucidating its mechanism of action.
