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奶牛乳房健康基因检测芯片在中国荷斯坦牛及巴基斯坦本地奶牛群中的应用研究
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作者 赖婉仪 陶欣月 +4 位作者 杨庚新 余文莉 李树静 Tahir Usman 俞英 《畜牧兽医学报》 CAS CSCD 北大核心 2024年第10期4489-4499,共11页
旨在筛选与奶牛乳房健康相关的SNP位点或组合,提升奶牛乳房健康水平,同时促进“一带一路”国家的奶牛产业健康发展。本研究基于1097头中国荷斯坦牛、161头巴基斯坦荷斯坦牛的尾静脉血及116头Achai牛、104头辛地红牛的尾根毛囊,提取基因... 旨在筛选与奶牛乳房健康相关的SNP位点或组合,提升奶牛乳房健康水平,同时促进“一带一路”国家的奶牛产业健康发展。本研究基于1097头中国荷斯坦牛、161头巴基斯坦荷斯坦牛的尾静脉血及116头Achai牛、104头辛地红牛的尾根毛囊,提取基因组DNA,使用奶牛乳房健康分子检测芯片(Chinese Cow's SNPs Chip-Ⅰ,CCSC-Ⅰ)获得基因型,结合相应DHI数据报告中的乳房健康指标——体细胞数(somatic cell count,SCC)及体细胞评分(somatic cell score,SCS),通过单个SNP和成对SNP关联分析,鉴定有意义的SNP位点或组合。单位点关联分析结果显示,SNP3、6、8、11、19、20在中国荷斯坦牛群体中为显著位点(P<0.05),针对巴基斯坦奶牛群同样鉴定出SNP3和SNP11为显著位点(P<0.05);在成对位点关联分析中,中国荷斯坦牛群体使用大样本(北京、浙江、河北地区牧场)和河北地区样本分别分析,保留稳定的SNP11-SNP15组合,SNP19和SNP20的AA基因型同占优势,针对巴基斯坦荷斯坦牛鉴定了SNP11-SNP2、4、8、9、12、16、19等极显著组合(P<0.01),而针对巴基斯坦本地奶牛Achai鉴定出了SNP3-SNP11、15等极显著组合(P<0.01)。本研究结果显示,奶牛乳房健康分子检测芯片具有广泛适用性。SNP11、15、19、20等位点对奶牛乳房健康具有重要影响。在荷斯坦牛群体中,CD4、TRAPPC9和PTK2基因表现出潜在的乳房炎抗性;而在巴基斯坦本地奶牛中,CD4、DGAT1和TRAPPC9基因则表现出显著的抗性特征。这些发现为未来的精准选育提供了有力的科学依据。 展开更多
关键词 中国荷斯坦牛 巴基斯坦荷斯坦牛 巴基斯坦本地奶牛 奶牛乳房炎 单核苷酸多态性
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引进良种公牛对本地奶牛改良的效果分析
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作者 赵亮 郑关章 《养殖技术顾问》 2003年第3期1-1,共1页
关键词 良种公牛 本地奶牛 杂交改良 生产性能
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Comparison the Genetic Potential of Some Growth & Milk Trait, s of Hybrid (Crossed) Saanen with Native Goat (Lori Black Goat) versus Native Goats in Qom Province
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作者 S. M. Hoseini Ghazikhani M. Kalantar 《Journal of Agricultural Science and Technology(A)》 2011年第8期1297-1299,共3页
The performance of some growth and milk traits of selected Qomi native (Lori black) goats and hybrids of saanen with native goats during 2008-2010 was compared. Growth traits include birth weight (BW), one-month w... The performance of some growth and milk traits of selected Qomi native (Lori black) goats and hybrids of saanen with native goats during 2008-2010 was compared. Growth traits include birth weight (BW), one-month weight (1 MW), weaning weight (WW) and 6-month weight (6 MW). Also the milk production traits was monthly milk production on 2, 3, 4, 5th months (quantitative traits) and some milk composition included dry matter (%DM), fat (%F), and protein (%P) percentage on during of production (qualitative traits). There were no significant differences in sex, birth type and genetic group for BW. Also the effect of genetic groups on 1 MW, WW, and 6 MW was significant, while effects of sex and birth type on 1 MW, WW and 6 MW was not significant. Also MW (Mothe's weight) had no significant effect on BW, 1 MW, WW and 6 MW. The average of daily milk records was 0.48 kg for nativel and 1.1 kg for crossed goats. The maximum monthly milk records in two groups were in second month (native: 0.64 -4- 0.05, crossed: 1.44 ~: 0.12) and the minimum were in fifth month (native: 0.36 + 0.03, crossed: 0.77 -4- 0.05). %DM, %F and %P in 5th month were higher than other months in two groups. Effects of genetic groups on milk production and also on average of%F, %DM and %P were significant. This study showed that the crossbreeding has a significant effect on most milk production and growth traits in Iranian native goats. 展开更多
关键词 Saanen goat qomi native goat growth traits milk traits
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