Since the first human case of H5N1 avian influenza virus infection was reported in 1997, this highly pathogenic virus has infected hundreds of people around the world and resulted in many deaths. The ability of H5N1 t...Since the first human case of H5N1 avian influenza virus infection was reported in 1997, this highly pathogenic virus has infected hundreds of people around the world and resulted in many deaths. The ability of H5N1 to cross species boundaries, and the presence of polymorphisms that enhance virulence, present challenges to developing clear strategies to prevent the pandemic spread of this highly pathogenic avian influenza (HPAI) virus. This review summarizes the current understanding of, and recent research on, the avian influenza H5N1 virus, including transmission, virulence, pathogenesis, clinical characteristics, treatment and prevention.展开更多
In this paper, we explore the diagnosis and treatment of hemangiopedcytoma （HPC）. A rare case of HPC in the vertebral canal of thoracic segments is reported, and the clinical features as well as treatment approaches...In this paper, we explore the diagnosis and treatment of hemangiopedcytoma （HPC）. A rare case of HPC in the vertebral canal of thoracic segments is reported, and the clinical features as well as treatment approaches of similar cases in the literature are discussed. In the present case, we operatively resected the tumor and performed postoperative radiation therapy, with good treatment results.展开更多
Haemangiopericytoma(HPC) is a rare vascular tumor with borderline malignancy, considerable histological variability, and unpredictable clinical and biological behavior. HPC can present a diagnostic challenge because o...Haemangiopericytoma(HPC) is a rare vascular tumor with borderline malignancy, considerable histological variability, and unpredictable clinical and biological behavior. HPC can present a diagnostic challenge because of its indeterminate clinical, radiological, and pathological features. HPC generally presents in adulthood and is equally frequent in both sexes. HPC can arise in any site in the body as a slowly growing and painless mass. The precise cell type origin of HPC is uncertain. One third of HPCs occur in the head and neck areas. Exceptional cases of hemangioblastoma arising outside the head and neck areas have been reported, but little is known about their clinicopathologic and immunohistochemical features. This study reports on a case of a large sacro-anterior HPC in a 65-year-old male.展开更多
Objective:This study summarizes and compares clinical and laboratory characteristics of 34 patients admitted to the intensive care unit(ICU)for complications from coronavirus disease 2019(COVID-19)at the First Affilia...Objective:This study summarizes and compares clinical and laboratory characteristics of 34 patients admitted to the intensive care unit(ICU)for complications from coronavirus disease 2019(COVID-19)at the First Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,China from Jan.22 to Mar.5,2020.Methods:A total of 34 patients were divided into two groups,including those who required noninvasive ventilation(NIV)and invasive mechanical ventilation(IMV)with additional extracorporeal membrane oxygenation(ECMO)in 11 patients.Clinical features of COVID-19 patients were described and the parameters of clinical characteristics between the two groups were compared.Results:The rates of the acute cardiac and kidney complications were higher in IMV cases than those in NIV cases.Most patients had lymphocytopenia on admission,with lymphocyte levels dropping progressively on the following days,and the more severe lymphopenia developed in the IMV group.In both groups,T lymphocyte counts were below typical lower limit norms compared to B lymphocytes.On admission,both groups had higher than expected amounts of plasma interleukin-6(IL-6),which over time declined more in NIV patients.The prothrombin time was increased and the levels of platelet,hemoglobin,blood urea nitrogen(BUN),D-dimer,lactate dehydrogenase(LDH),and IL-6 were higher in IMV cases compared with NIV cases during hospitalization.Conclusions:Data showed that the rates of complications,dynamics of lymphocytopenia,and changes in levels of platelet,hemoglobin,BUN,D-dimer,LDH and IL-6,and prothrombin time in these ICU patients were significantly different between IMV and NIV cases.展开更多
Acupoints are particular areas on the surface of the body through which the Qi and blood of the Zang-fu organs and meridians flow.Acupoints can respond to stimuli and reflect syndromes.Research on the essential morpho...Acupoints are particular areas on the surface of the body through which the Qi and blood of the Zang-fu organs and meridians flow.Acupoints can respond to stimuli and reflect syndromes.Research on the essential morphology of acupoints has two key focuses:anatomical structure and physiological function.The structure is the material and anatomical basis for the function,while the function is the manifestation of the structure.The two factors not only have profound significance for our understanding of the essence of acupoints,but also have great value for clinical acupuncture and moxibustion practice.Based on the structural and functional characteristics of meridians under different physiological and pathological conditions,this paper illustrates the essence of acupoints and explores the rules and biological basis of the acupoint functions induced by acupuncture and moxibustion.展开更多
基金National Natural Science Foundation of China (30979144 and 81271821)
文摘Since the first human case of H5N1 avian influenza virus infection was reported in 1997, this highly pathogenic virus has infected hundreds of people around the world and resulted in many deaths. The ability of H5N1 to cross species boundaries, and the presence of polymorphisms that enhance virulence, present challenges to developing clear strategies to prevent the pandemic spread of this highly pathogenic avian influenza (HPAI) virus. This review summarizes the current understanding of, and recent research on, the avian influenza H5N1 virus, including transmission, virulence, pathogenesis, clinical characteristics, treatment and prevention.
文摘In this paper, we explore the diagnosis and treatment of hemangiopedcytoma （HPC）. A rare case of HPC in the vertebral canal of thoracic segments is reported, and the clinical features as well as treatment approaches of similar cases in the literature are discussed. In the present case, we operatively resected the tumor and performed postoperative radiation therapy, with good treatment results.
文摘Haemangiopericytoma(HPC) is a rare vascular tumor with borderline malignancy, considerable histological variability, and unpredictable clinical and biological behavior. HPC can present a diagnostic challenge because of its indeterminate clinical, radiological, and pathological features. HPC generally presents in adulthood and is equally frequent in both sexes. HPC can arise in any site in the body as a slowly growing and painless mass. The precise cell type origin of HPC is uncertain. One third of HPCs occur in the head and neck areas. Exceptional cases of hemangioblastoma arising outside the head and neck areas have been reported, but little is known about their clinicopathologic and immunohistochemical features. This study reports on a case of a large sacro-anterior HPC in a 65-year-old male.
基金the Project for Emergency of Key R&D Plan from Zhejiang Science and Technology Agency(No.2020C03123),China。
文摘Objective:This study summarizes and compares clinical and laboratory characteristics of 34 patients admitted to the intensive care unit(ICU)for complications from coronavirus disease 2019(COVID-19)at the First Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,China from Jan.22 to Mar.5,2020.Methods:A total of 34 patients were divided into two groups,including those who required noninvasive ventilation(NIV)and invasive mechanical ventilation(IMV)with additional extracorporeal membrane oxygenation(ECMO)in 11 patients.Clinical features of COVID-19 patients were described and the parameters of clinical characteristics between the two groups were compared.Results:The rates of the acute cardiac and kidney complications were higher in IMV cases than those in NIV cases.Most patients had lymphocytopenia on admission,with lymphocyte levels dropping progressively on the following days,and the more severe lymphopenia developed in the IMV group.In both groups,T lymphocyte counts were below typical lower limit norms compared to B lymphocytes.On admission,both groups had higher than expected amounts of plasma interleukin-6(IL-6),which over time declined more in NIV patients.The prothrombin time was increased and the levels of platelet,hemoglobin,blood urea nitrogen(BUN),D-dimer,lactate dehydrogenase(LDH),and IL-6 were higher in IMV cases compared with NIV cases during hospitalization.Conclusions:Data showed that the rates of complications,dynamics of lymphocytopenia,and changes in levels of platelet,hemoglobin,BUN,D-dimer,LDH and IL-6,and prothrombin time in these ICU patients were significantly different between IMV and NIV cases.
基金supported by the Key Project of National Natural Science Foundation of China(81130063)the 973 Project(2012CB 518503)
文摘Acupoints are particular areas on the surface of the body through which the Qi and blood of the Zang-fu organs and meridians flow.Acupoints can respond to stimuli and reflect syndromes.Research on the essential morphology of acupoints has two key focuses:anatomical structure and physiological function.The structure is the material and anatomical basis for the function,while the function is the manifestation of the structure.The two factors not only have profound significance for our understanding of the essence of acupoints,but also have great value for clinical acupuncture and moxibustion practice.Based on the structural and functional characteristics of meridians under different physiological and pathological conditions,this paper illustrates the essence of acupoints and explores the rules and biological basis of the acupoint functions induced by acupuncture and moxibustion.
