Atrial fibrosis is common in atrial fibrillation (AF). Experimental studies have provided convincing evidence that fibrotic transformation of atrial myocardium results in deterioration of atrial conduction, increasi...Atrial fibrosis is common in atrial fibrillation (AF). Experimental studies have provided convincing evidence that fibrotic transformation of atrial myocardium results in deterioration of atrial conduction, increasing anisotropy of impulse propagation and building of boundaries that promote re-entry in the atrial walls that maybe directly relevant for the mechanisms responsible for maintaining AF. Whether or not fibrosis is a result of structural remodelling caused by persistent AF or a manifestation of occult myocardial process that leads to development of arrhythmia is less clear. Human data indicate the presence of association between persistency of AF and the extent of structural changes in atrial myocardium. The role atrial fibrosis plays in the mechanisms of AF, however, may differ between patients with structurally normal hearts, such as lone AF, and those with advanced cardiovascular comorbidities.展开更多
With the increasing requirement of a higher living quality and the growing awareness of energy saving, how to improve the indoor comfort level and to reduce the expenditure of energy and slow down the rate of natural ...With the increasing requirement of a higher living quality and the growing awareness of energy saving, how to improve the indoor comfort level and to reduce the expenditure of energy and slow down the rate of natural resource consumption is becoming increasingly important. The theory of open-plan housing is able to provide a more flexible and adaptive space for the users and bring sustainable and economic benefit in the way of making full use of construction materials. Sustainable architecture design, as a method to respond the phenomenon, is able to low down the building' s energy consumption and has enormous potentials in creation of sustainable living environment and a high-quality dwelling condition. The primary aim of this research is to create a new sustainable architecture design method for occupancy by integrating openplan housing theory and application of sustainable technologies. Numerical simulation by computer program is applied in order to investigate and evaluate the possibility of this method in teruas of improving indoor comfort level and energy-saving capacity.展开更多
文摘Atrial fibrosis is common in atrial fibrillation (AF). Experimental studies have provided convincing evidence that fibrotic transformation of atrial myocardium results in deterioration of atrial conduction, increasing anisotropy of impulse propagation and building of boundaries that promote re-entry in the atrial walls that maybe directly relevant for the mechanisms responsible for maintaining AF. Whether or not fibrosis is a result of structural remodelling caused by persistent AF or a manifestation of occult myocardial process that leads to development of arrhythmia is less clear. Human data indicate the presence of association between persistency of AF and the extent of structural changes in atrial myocardium. The role atrial fibrosis plays in the mechanisms of AF, however, may differ between patients with structurally normal hearts, such as lone AF, and those with advanced cardiovascular comorbidities.
文摘With the increasing requirement of a higher living quality and the growing awareness of energy saving, how to improve the indoor comfort level and to reduce the expenditure of energy and slow down the rate of natural resource consumption is becoming increasingly important. The theory of open-plan housing is able to provide a more flexible and adaptive space for the users and bring sustainable and economic benefit in the way of making full use of construction materials. Sustainable architecture design, as a method to respond the phenomenon, is able to low down the building' s energy consumption and has enormous potentials in creation of sustainable living environment and a high-quality dwelling condition. The primary aim of this research is to create a new sustainable architecture design method for occupancy by integrating openplan housing theory and application of sustainable technologies. Numerical simulation by computer program is applied in order to investigate and evaluate the possibility of this method in teruas of improving indoor comfort level and energy-saving capacity.