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90Y微球中放射性杂质核素对胰腺肿瘤治疗剂量的影响
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作者 罗文 郭金森 +1 位作者 王薇 陈凌 《中国辐射卫生》 2024年第3期242-247,共6页
目的评估90Y玻璃微球放射性栓塞治疗胰腺癌时,90Y玻璃微球中放射性杂质核素对治疗剂量的影响,可为解决因胰腺肿瘤个体差异化带来的剂量准确计算提供修正参考。方法本文首先分析90Y玻璃微球样本中放射性杂质核素成分,确定蒙特卡洛计算的... 目的评估90Y玻璃微球放射性栓塞治疗胰腺癌时,90Y玻璃微球中放射性杂质核素对治疗剂量的影响,可为解决因胰腺肿瘤个体差异化带来的剂量准确计算提供修正参考。方法本文首先分析90Y玻璃微球样本中放射性杂质核素成分,确定蒙特卡洛计算的源项信息,然后根据胰腺癌患者的PET/CT医学影像资料和数据,采用三维造型软件Solidworks 2020构建胰腺癌患者真实个性化数字人体消化系统模型,细化到胰腺和肿瘤的血管分布,最后采用蒙特卡洛程序GATE 8.2对90Y玻璃微球中放射性杂质核素91Y、65Zn在各组织或器官中的三维辐射剂量场进行模拟计算,并对三维剂量场进行可视化,分析放射性杂质核素对治疗剂量的影响。结果90Y玻璃微球中放射性杂质核素91Y、65Zn在组织中三维辐射剂量场内部均形成2个剂量极值点,91Y核素对组织的最大剂量值为0.272 mGy,65Zn核素对组织的最大剂量值为9.34μGy,平均统计误差均在3.2%以内。结论90Y玻璃微球样本中放射性杂质核素91Y、65Zn对该胰腺癌患者的治疗剂量影响很小,可忽略不计。 展开更多
关键词 90Y玻璃微球 杂质核素 胰腺癌 剂量计算
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Experimental Results on Excess Heat Power, Impurity Nuclides and X-Ray Production in Experiments with a High-Voltage Electric Discharge System
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作者 Alexander Karabut 《Journal of Physical Science and Application》 2014年第2期71-83,共13页
It reviewed results on low-energy nuclear reaction (LENR) processes in a high-voltage (1,000-4,000 V) electric discharge system. The experimental results are divided into three sets: excess heat measurements; yie... It reviewed results on low-energy nuclear reaction (LENR) processes in a high-voltage (1,000-4,000 V) electric discharge system. The experimental results are divided into three sets: excess heat measurements; yield of impurity nuclides (nuclear ash); X-ray measurements. Up to 8 W of excess power was observed, with a power gain of up to 170% was seen in glow discharge experiments. Up to 300 W of excess power, with a power gain up to 340% was observed in experiments using a high-voltage electrolysis cell. The impurity nuclide yield showing a shift of up to a few per cent from natural isotopic abundances was detected by spark mass spectrometry, by secondary ionic mass spectrometry, and by secondary neutral mass spectrometry. X-ray emission in the range of 0.6-6.0 keV, has been observed. Based on these experimental results we propose a phenomenological model for LENR based on the interaction of an electric discharge with condensed matter (of the cathode). 展开更多
关键词 Electric discharge excess heat impurity nuclides X-ray emission
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