AIM: To investigate the anti-neoplastic effects of MK615, an extract from the Japanese apricot (Prunus mume), against colon cancer cells. METHODS: Three colon cancer cell lines, SW480, COLO, and WiDr, were cultured wi...AIM: To investigate the anti-neoplastic effects of MK615, an extract from the Japanese apricot (Prunus mume), against colon cancer cells. METHODS: Three colon cancer cell lines, SW480, COLO, and WiDr, were cultured with MK615. Growth inhibition was evaluated by cell proliferation assay and killing activity was determined by lactate dehydrogenase assay. Induction of apoptosis was evaluated by annexin Ⅴ flow cytometry. Morphological changes were studied by light and electron microscopy, and immunofluorescence staining with Atg8. RESULTS: MK615 inhibited growth and lysed SW480, COLO and WiDr cells in a dose-dependent manner. Annexin Ⅴ flow cytometry showed that MK615 induced apoptosis after 6 h incubation, at which point the occurrence of apoptotic cells was 68.0%, 65.7% and 64.7% for SW480, COLO, and WiDr cells, respectively. Light and electron microscopy, and immunofluorescence staining with Atg8 revealed that MK615 induced massive cytoplasmic vacuoles (autophagosomes) in all three cell lines. CONCLUSION: MK615 has an anti-neoplastic effect against colon cancer cells. The effect may be exerted by induction of apoptosis and autophagy.展开更多
Two new explicit Lie algebras are introduced for which the nonlinear integrable couplings of the Giachetti- Johnson (G J) hierarchy and the Yang hierarchy are obtained, respectively. By employing the variational ide...Two new explicit Lie algebras are introduced for which the nonlinear integrable couplings of the Giachetti- Johnson (G J) hierarchy and the Yang hierarchy are obtained, respectively. By employing the variational identity their ttamiltonian structures are also generated. The approach presented in the paper can also provide nonlinear integrable couplings of other soliton hierarchies of evolution equations.展开更多
By using a Lie algebra, an integrable couplings of the classicai-Boussinesq hierarchy is obtained. Then, the Hamiltonian structure of the integrable couplings of the classical-Boussinesq is obtained by the quadratic-f...By using a Lie algebra, an integrable couplings of the classicai-Boussinesq hierarchy is obtained. Then, the Hamiltonian structure of the integrable couplings of the classical-Boussinesq is obtained by the quadratic-form identity.展开更多
A new Lie algebra G of the Lie algebra sl(2) is constructed with complex entries whose structure constants are real and imaginary numbers. A loop algebra G corresponding to the Lie algebra G is constructed, for whic...A new Lie algebra G of the Lie algebra sl(2) is constructed with complex entries whose structure constants are real and imaginary numbers. A loop algebra G corresponding to the Lie algebra G is constructed, for which it is devoted to generating a soliton hierarchy of evolution equations under the framework of generalized zero curvature equation which is derived from the compatibility of the isospectral problems expressed by Hirota operators. Finally, we decompose the Lie algebra G to obtain the subalgebras G1 and G2. Using the G2 and its one type of loop algebra G2, a Liouville integrable soliton hierarchy is obtained, furthermore, we obtain its bi-Hamiltonian structure by employing the quadratic-form identity.展开更多
Firstly 4 Lie algebras are constructed. Then applications of the loop algebra are presented to obtain two types of coupling integrable couplings of the S-mKdV hierarchy by using Tu scheme. The coupling integrable coup...Firstly 4 Lie algebras are constructed. Then applications of the loop algebra are presented to obtain two types of coupling integrable couplings of the S-mKdV hierarchy by using Tu scheme. The coupling integrable couplings of the S-mKdV hierarchy obtained in the paper reduce to the coupling integrable couplings of the mKdV equation and the coupling integrable couplings of the nonlinear Schrodinger equation respectively. The method given in the paper can be used to other hierarchies generally.展开更多
This article focuses on the study of stability of motion of the phase systems described by differential equations whose right-hand sides are periodic in the angular coordinate. The article deals with the mathematical ...This article focuses on the study of stability of motion of the phase systems described by differential equations whose right-hand sides are periodic in the angular coordinate. The article deals with the mathematical model which has been investigated for stability "in the large" using the second Lyapunov method. Based on the theoretical results obtained in the work,the computational experiments on concrete examples of electric power systems, which showedthe sufficient efficacy of the proposed method for the studied phase system, were conducted.展开更多
This paper deals with the robust stabilization problem for a class of nonlinear systems with structural uncertainty. Based on robust control Lyapunov function, a sufficient and necessary condition for a function to be...This paper deals with the robust stabilization problem for a class of nonlinear systems with structural uncertainty. Based on robust control Lyapunov function, a sufficient and necessary condition for a function to be a robust control Lyapunov function is given. From this condition, simply sufficient condition for the robust stabilization (robust practical stabilization) is deduced. Moreover, if the equilibrium of the closed-loop system is unique, the existence of such a robust control Lyapunnv function will also imply robustly globally asymptotical stabilization. Then a continuous state feedback law can be constructed explicitly. The simulation shows the effectiveness of the method.展开更多
Liouville integrable discrete integrable system is derived based on discrete isospectral problem. It is shown that the hierarchy is completely integrable in the Liouville sense and possesses bi-Hamiltonian structure. ...Liouville integrable discrete integrable system is derived based on discrete isospectral problem. It is shown that the hierarchy is completely integrable in the Liouville sense and possesses bi-Hamiltonian structure. Finally, integrable couplings of the obtained system is given by means of semi-direct sums of Lie algebras.展开更多
With the help of a Lie algebra, an isospectral Lax pair is introduced for which a new Liouville integrable hierarchy of evolution equations is generated. Its Hamiltonian structure is also worked out by use of the quad...With the help of a Lie algebra, an isospectral Lax pair is introduced for which a new Liouville integrable hierarchy of evolution equations is generated. Its Hamiltonian structure is also worked out by use of the quadratic-form identity.展开更多
Two different integrable couplings of the modified Tu hierarchy are obtained under the zero curvatureequation by using two higher dimension Lie algebras.Furthermore,a complex Hamiltonian structures of the secondintegr...Two different integrable couplings of the modified Tu hierarchy are obtained under the zero curvatureequation by using two higher dimension Lie algebras.Furthermore,a complex Hamiltonian structures of the secondintegrable couplings is presented by taking use of the variational identity.展开更多
From a new Lie algebra proposed by Zhang, two expanding Lie algebras and its corresponding loop algebrasare obtained.Two expanding integrable systems are produced with the help of the generalized zero curvature equati...From a new Lie algebra proposed by Zhang, two expanding Lie algebras and its corresponding loop algebrasare obtained.Two expanding integrable systems are produced with the help of the generalized zero curvature equation.One of them has complex Hamiltion structure with the help of generalized Tu formula (GTM).展开更多
It is proved that, any finite dimensional complex Lie algebra/~ = [Z:, ~:], hence, over a field of characteristic zero, any finite dimensional Lie algebra l: = [/2, ~:] possessing a basis with complex structure co...It is proved that, any finite dimensional complex Lie algebra/~ = [Z:, ~:], hence, over a field of characteristic zero, any finite dimensional Lie algebra l: = [/2, ~:] possessing a basis with complex structure constants, should be a weak co-split Lie algebra. A class of non-semi-simple co-split Lie algebras is given.展开更多
In this paper, the dispersionless D-type Drinfeld–Sokolov hierarchy, i.e. a reduction of the dispersionless two-component BKP hierarchy, is studied. The additional symmetry flows of this hierarchy are presented. Thes...In this paper, the dispersionless D-type Drinfeld–Sokolov hierarchy, i.e. a reduction of the dispersionless two-component BKP hierarchy, is studied. The additional symmetry flows of this hierarchy are presented. These flows form an infinite-dimensional Lie algebra of Block type as well as a Lie algebra of Hamiltonian type.展开更多
We construct nonlinear super integrable couplings of the super integrable Dirac hierarchy based on an enlarged matrix Lie superalgebra.Then its super Hamiltonian structure is furnished by super trace identity.As its r...We construct nonlinear super integrable couplings of the super integrable Dirac hierarchy based on an enlarged matrix Lie superalgebra.Then its super Hamiltonian structure is furnished by super trace identity.As its reduction,we gain the nonlinear integrable couplings of the classical integrable Dirac hierarchy.展开更多
Based on a kind of Lie a/gebra G proposed by Zhang, one isospectral problem is designed. Under the framework of zero curvature equation, a new kind of integrable coupling of an equation hierarchy is generated using th...Based on a kind of Lie a/gebra G proposed by Zhang, one isospectral problem is designed. Under the framework of zero curvature equation, a new kind of integrable coupling of an equation hierarchy is generated using the methods proposed by Ma and Gao. With the help of variational identity, we get the Hamiltonian structure of the hierarchy.展开更多
We propose a systematic approach for generating Hamiltonian tri-integrable couplings of soliton hierarchies. The resulting approach is based on semi-direct sums of matrix Lie algebras consisting of 4× 4 block mat...We propose a systematic approach for generating Hamiltonian tri-integrable couplings of soliton hierarchies. The resulting approach is based on semi-direct sums of matrix Lie algebras consisting of 4× 4 block matrix Lie algebras. We apply the approach to the AKNS soIRon hierarchy, and Hamiltonian structures of the obtained tri-integrable couplings are constructed by the variational identity.展开更多
We introduce two operator commutators by using different-degree loop algebras of the Lie algebra A1,then under the framework of zero curvature equations we generate two(2+1)-dimensional integrable hierarchies, includi...We introduce two operator commutators by using different-degree loop algebras of the Lie algebra A1,then under the framework of zero curvature equations we generate two(2+1)-dimensional integrable hierarchies, including the(2+1)-dimensional shallow water wave(SWW) hierarchy and the(2+1)-dimensional Kaup–Newell(KN)hierarchy. Through reduction of the(2+1)-dimensional hierarchies, we get a(2+1)-dimensional SWW equation and a(2+1)-dimensional KN equation. Furthermore, we obtain two Darboux transformations of the(2+1)-dimensional SWW equation. Similarly, the Darboux transformations of the(2+1)-dimensional KN equation could be deduced. Finally,with the help of the spatial spectral matrix of SWW hierarchy, we generate a(2+1) heat equation and a(2+1) nonlinear generalized SWW system containing inverse operators with respect to the variables x and y by using a reduction spectral problem from the self-dual Yang–Mills equations.展开更多
文摘AIM: To investigate the anti-neoplastic effects of MK615, an extract from the Japanese apricot (Prunus mume), against colon cancer cells. METHODS: Three colon cancer cell lines, SW480, COLO, and WiDr, were cultured with MK615. Growth inhibition was evaluated by cell proliferation assay and killing activity was determined by lactate dehydrogenase assay. Induction of apoptosis was evaluated by annexin Ⅴ flow cytometry. Morphological changes were studied by light and electron microscopy, and immunofluorescence staining with Atg8. RESULTS: MK615 inhibited growth and lysed SW480, COLO and WiDr cells in a dose-dependent manner. Annexin Ⅴ flow cytometry showed that MK615 induced apoptosis after 6 h incubation, at which point the occurrence of apoptotic cells was 68.0%, 65.7% and 64.7% for SW480, COLO, and WiDr cells, respectively. Light and electron microscopy, and immunofluorescence staining with Atg8 revealed that MK615 induced massive cytoplasmic vacuoles (autophagosomes) in all three cell lines. CONCLUSION: MK615 has an anti-neoplastic effect against colon cancer cells. The effect may be exerted by induction of apoptosis and autophagy.
基金Supported by the Fundamental Research Funds of the Central University under Grant No. 2010LKS808the Natural Science Foundation of Shandong Province under Grant No. ZR2009AL021
文摘Two new explicit Lie algebras are introduced for which the nonlinear integrable couplings of the Giachetti- Johnson (G J) hierarchy and the Yang hierarchy are obtained, respectively. By employing the variational identity their ttamiltonian structures are also generated. The approach presented in the paper can also provide nonlinear integrable couplings of other soliton hierarchies of evolution equations.
基金Supported by the Natural Science Foundation of Shanghai under Grant No.09ZR1410800the Science Foundation of Key Laboratory of Mathematics Mechanization under Grant No.KLMM0806+1 种基金the Shanghai Leading Academic Discipline Project under Grant No.J50101Key Disciplines of Shanghai Municipality (S30104)
文摘By using a Lie algebra, an integrable couplings of the classicai-Boussinesq hierarchy is obtained. Then, the Hamiltonian structure of the integrable couplings of the classical-Boussinesq is obtained by the quadratic-form identity.
基金supported by the National Natural Science Foundation of China under Grant No.10471139
文摘A new Lie algebra G of the Lie algebra sl(2) is constructed with complex entries whose structure constants are real and imaginary numbers. A loop algebra G corresponding to the Lie algebra G is constructed, for which it is devoted to generating a soliton hierarchy of evolution equations under the framework of generalized zero curvature equation which is derived from the compatibility of the isospectral problems expressed by Hirota operators. Finally, we decompose the Lie algebra G to obtain the subalgebras G1 and G2. Using the G2 and its one type of loop algebra G2, a Liouville integrable soliton hierarchy is obtained, furthermore, we obtain its bi-Hamiltonian structure by employing the quadratic-form identity.
基金Supported by National Natural Science Foundation of China under Grant No. 10901090, the Natural Science Foundation of Shandong Province under Grant No. ZR2010AM029, and the Innovative Scientific Research Projects of Young of Binzhou University (BZXYQNLG200725)
文摘Firstly 4 Lie algebras are constructed. Then applications of the loop algebra are presented to obtain two types of coupling integrable couplings of the S-mKdV hierarchy by using Tu scheme. The coupling integrable couplings of the S-mKdV hierarchy obtained in the paper reduce to the coupling integrable couplings of the mKdV equation and the coupling integrable couplings of the nonlinear Schrodinger equation respectively. The method given in the paper can be used to other hierarchies generally.
文摘This article focuses on the study of stability of motion of the phase systems described by differential equations whose right-hand sides are periodic in the angular coordinate. The article deals with the mathematical model which has been investigated for stability "in the large" using the second Lyapunov method. Based on the theoretical results obtained in the work,the computational experiments on concrete examples of electric power systems, which showedthe sufficient efficacy of the proposed method for the studied phase system, were conducted.
基金Sponsored by the Natural Science Foundation of Zhejiang Province in China(Grant No. Y105141).
文摘This paper deals with the robust stabilization problem for a class of nonlinear systems with structural uncertainty. Based on robust control Lyapunov function, a sufficient and necessary condition for a function to be a robust control Lyapunov function is given. From this condition, simply sufficient condition for the robust stabilization (robust practical stabilization) is deduced. Moreover, if the equilibrium of the closed-loop system is unique, the existence of such a robust control Lyapunnv function will also imply robustly globally asymptotical stabilization. Then a continuous state feedback law can be constructed explicitly. The simulation shows the effectiveness of the method.
文摘Liouville integrable discrete integrable system is derived based on discrete isospectral problem. It is shown that the hierarchy is completely integrable in the Liouville sense and possesses bi-Hamiltonian structure. Finally, integrable couplings of the obtained system is given by means of semi-direct sums of Lie algebras.
文摘With the help of a Lie algebra, an isospectral Lax pair is introduced for which a new Liouville integrable hierarchy of evolution equations is generated. Its Hamiltonian structure is also worked out by use of the quadratic-form identity.
文摘Two different integrable couplings of the modified Tu hierarchy are obtained under the zero curvatureequation by using two higher dimension Lie algebras.Furthermore,a complex Hamiltonian structures of the secondintegrable couplings is presented by taking use of the variational identity.
基金Supported in part by National Natural Science Foundation of China under Grant No. 10971071the Outstanding Youth Fund of Henan Province under Grant No. 0512000100Innovation Fund of Colleges and Universities in Henan Province
文摘In this paper, we construct a new algebra structure 7-twisted atone Lie algebra sl(3,C)[θ] and study its vertex operator representations.
基金Supported by the Natural Science Foundation of China under Grant Nos.60971022,61072147,and 11071159the Natural Science Foundation of Shanghai under Grant No.09ZR1410800+1 种基金the Shanghai Leading Academic Discipline Project under Grant No.J50101the National Key Basic Research Project of China under Grant No.KLMM0806
文摘From a new Lie algebra proposed by Zhang, two expanding Lie algebras and its corresponding loop algebrasare obtained.Two expanding integrable systems are produced with the help of the generalized zero curvature equation.One of them has complex Hamiltion structure with the help of generalized Tu formula (GTM).
基金Project supported by the National Natural Science Foundation of China (No. 11001110)
文摘It is proved that, any finite dimensional complex Lie algebra/~ = [Z:, ~:], hence, over a field of characteristic zero, any finite dimensional Lie algebra l: = [/2, ~:] possessing a basis with complex structure constants, should be a weak co-split Lie algebra. A class of non-semi-simple co-split Lie algebras is given.
基金Supported by the National Natural Science Foundation of China under Grant No.11201251the National Natural Science Foundation of China under Grant No.11271210+5 种基金Zhejiang Provincial Natural Science Foundation under Grant No.LY12A01007the Natural Science Foundation of Ningbo under Grant No.2013A610105K.C.Wong Magna Fund in Ningbo Universitythe National Science Foundation of China under Grant No.11371278the Shanghai Municipal Science and Technology Commission under Grant No.12XD1405000the Fundamental Research Funds for the Central Universities of China
文摘In this paper, the dispersionless D-type Drinfeld–Sokolov hierarchy, i.e. a reduction of the dispersionless two-component BKP hierarchy, is studied. The additional symmetry flows of this hierarchy are presented. These flows form an infinite-dimensional Lie algebra of Block type as well as a Lie algebra of Hamiltonian type.
基金Supported by the Natural Science Foundation of China under Grant No. 60972164the Program for Liaoning Excellent Talents in University under Grant No. LJQ2011136+2 种基金the Key Technologies R&D Program of Liaoning Province under Grant No. 2011224006the Program for Liaoning Innovative Research Team in University under Grant No. LT2011019the Science and Technology Program of Shenyang under Grant No. F11-264-1-70
文摘We construct nonlinear super integrable couplings of the super integrable Dirac hierarchy based on an enlarged matrix Lie superalgebra.Then its super Hamiltonian structure is furnished by super trace identity.As its reduction,we gain the nonlinear integrable couplings of the classical integrable Dirac hierarchy.
基金Supported by the Natural Science Foundation of China under Grant Nos.11271008,61072147,11071159the Shanghai Leading Academic Discipline Project under Grant No.J50101the Shanghai Univ.Leading Academic Discipline Project(A.13-0101-12-004)
文摘Based on a kind of Lie a/gebra G proposed by Zhang, one isospectral problem is designed. Under the framework of zero curvature equation, a new kind of integrable coupling of an equation hierarchy is generated using the methods proposed by Ma and Gao. With the help of variational identity, we get the Hamiltonian structure of the hierarchy.
基金Supported in part by the Department of Mathematics and Statistics of University of South Floridathe State Administration of Foreign Experts Affairs of China+2 种基金the Natural Science Foundation of Shanghai under Grant No.09ZR1410800the Shanghai Leading Academic Discipline Project No.J50101the National Natural Science Foundation of China under Grant Nos.11271008,61072147,and11071159
文摘We propose a systematic approach for generating Hamiltonian tri-integrable couplings of soliton hierarchies. The resulting approach is based on semi-direct sums of matrix Lie algebras consisting of 4× 4 block matrix Lie algebras. We apply the approach to the AKNS soIRon hierarchy, and Hamiltonian structures of the obtained tri-integrable couplings are constructed by the variational identity.
基金Supported by the National Natural Science Foundation of China under Grant No.11371361the Shandong Provincial Natural Science Foundation of China under Grant Nos.ZR2012AQ011,ZR2013AL016,ZR2015EM042+2 种基金National Social Science Foundation of China under Grant No.13BJY026the Development of Science and Technology Project under Grant No.2015NS1048A Project of Shandong Province Higher Educational Science and Technology Program under Grant No.J14LI58
文摘We introduce two operator commutators by using different-degree loop algebras of the Lie algebra A1,then under the framework of zero curvature equations we generate two(2+1)-dimensional integrable hierarchies, including the(2+1)-dimensional shallow water wave(SWW) hierarchy and the(2+1)-dimensional Kaup–Newell(KN)hierarchy. Through reduction of the(2+1)-dimensional hierarchies, we get a(2+1)-dimensional SWW equation and a(2+1)-dimensional KN equation. Furthermore, we obtain two Darboux transformations of the(2+1)-dimensional SWW equation. Similarly, the Darboux transformations of the(2+1)-dimensional KN equation could be deduced. Finally,with the help of the spatial spectral matrix of SWW hierarchy, we generate a(2+1) heat equation and a(2+1) nonlinear generalized SWW system containing inverse operators with respect to the variables x and y by using a reduction spectral problem from the self-dual Yang–Mills equations.