目的:观察极低浓度罗哌卡因复合舒芬太尼用于产妇可行走腰硬联合麻醉分娩镇痛的临床疗效。方法:选取ASAⅠ~Ⅱ级,单胎头位初产妇510例,依据患者知情自愿原则,随机分为A组、B组、C组三组,均为170例。A组为对照组,采用非分娩镇痛;B组为对照...目的:观察极低浓度罗哌卡因复合舒芬太尼用于产妇可行走腰硬联合麻醉分娩镇痛的临床疗效。方法:选取ASAⅠ~Ⅱ级,单胎头位初产妇510例,依据患者知情自愿原则,随机分为A组、B组、C组三组,均为170例。A组为对照组,采用非分娩镇痛;B组为对照组,采用硬膜外麻醉,使用0.1%罗哌卡因复合舒芬太尼;C组为研究组,采用腰硬联合麻醉,使用0.0625%罗哌卡因复合舒芬太尼。观察、记录产妇镇痛后30 min疼痛评分(VAS)、下肢运动能力评分(Bromage评分)、活跃期时间、第二产程时间、新生儿低Apgar评分发生率、剖宫产率以及使用催产素情况。结果:B组、C组产妇在镇痛后30 min VAS评分显著优于A组;C组产妇在镇痛后30 min VAS评分、Bromage评分表现优于B组;剖宫产率B、C组优于A组;催产素使用率方面B组>C组>A组,差异均有统计学意义(P<0.05),活跃期时间B、C组优于A组(P<0.05),C组又优于B组(P<0.05),在第二产程时间、新生儿低Apgar评分方面三组产妇比较差异无统计学意义(P>0.05)。结论:极低浓度(0.0625%)罗哌卡因复合舒芬太尼用于可行走分娩镇痛具有良好的临床疗效,能有效的减轻产妇的疼痛,从而降低剖宫产率,此外产妇可自由行走,起到加速宫口扩张、缩短产程及降低催产素使用率作用,安全性高,值得临床推广。展开更多
The conductivities of LiBr, LiCl, and LiNO 3 in methanol, ethanol, 1-propanol, and 2-propanol (with electrolyte concentrations <0.08 mol·L-1 ) were determined at 298.15 K, 313.15 K, and 323.15 K at atmosphere ...The conductivities of LiBr, LiCl, and LiNO 3 in methanol, ethanol, 1-propanol, and 2-propanol (with electrolyte concentrations <0.08 mol·L-1 ) were determined at 298.15 K, 313.15 K, and 323.15 K at atmosphere pressure separately by using a conductivity meter. The conductivity data were correlated with Foss-Chen-Justice (FCJ) equation and the limiting molar conductivities were obtained. The mean ionic activity coefficients of the salts in the organic solvents were calculated according to the Debye-Hückel limiting law and Onsager-Falkenhangen equations. The calculated results were compared with those activity coefficients in literature.展开更多
文摘目的:观察极低浓度罗哌卡因复合舒芬太尼用于产妇可行走腰硬联合麻醉分娩镇痛的临床疗效。方法:选取ASAⅠ~Ⅱ级,单胎头位初产妇510例,依据患者知情自愿原则,随机分为A组、B组、C组三组,均为170例。A组为对照组,采用非分娩镇痛;B组为对照组,采用硬膜外麻醉,使用0.1%罗哌卡因复合舒芬太尼;C组为研究组,采用腰硬联合麻醉,使用0.0625%罗哌卡因复合舒芬太尼。观察、记录产妇镇痛后30 min疼痛评分(VAS)、下肢运动能力评分(Bromage评分)、活跃期时间、第二产程时间、新生儿低Apgar评分发生率、剖宫产率以及使用催产素情况。结果:B组、C组产妇在镇痛后30 min VAS评分显著优于A组;C组产妇在镇痛后30 min VAS评分、Bromage评分表现优于B组;剖宫产率B、C组优于A组;催产素使用率方面B组>C组>A组,差异均有统计学意义(P<0.05),活跃期时间B、C组优于A组(P<0.05),C组又优于B组(P<0.05),在第二产程时间、新生儿低Apgar评分方面三组产妇比较差异无统计学意义(P>0.05)。结论:极低浓度(0.0625%)罗哌卡因复合舒芬太尼用于可行走分娩镇痛具有良好的临床疗效,能有效的减轻产妇的疼痛,从而降低剖宫产率,此外产妇可自由行走,起到加速宫口扩张、缩短产程及降低催产素使用率作用,安全性高,值得临床推广。
文摘The conductivities of LiBr, LiCl, and LiNO 3 in methanol, ethanol, 1-propanol, and 2-propanol (with electrolyte concentrations <0.08 mol·L-1 ) were determined at 298.15 K, 313.15 K, and 323.15 K at atmosphere pressure separately by using a conductivity meter. The conductivity data were correlated with Foss-Chen-Justice (FCJ) equation and the limiting molar conductivities were obtained. The mean ionic activity coefficients of the salts in the organic solvents were calculated according to the Debye-Hückel limiting law and Onsager-Falkenhangen equations. The calculated results were compared with those activity coefficients in literature.
