用智慧和汗水浇铸企业大厦——从深圳煤矿机电设备公司的崛起看林利和的创业之道

随着改革开放一声春雷,在深圳这片荒漠的土地上,涌现出一批又一批埋头耕耘、艰苦开拓的“拓荒牛”,他们把自己的心血和汗水洒在这片刚从睡梦中惊醒的土地上,浇灌出一株株绚丽夺目的企业文明之花.深圳煤矿机电设备公司经理林利和同志,就是这些拓荒者中的成功的一员.他带领他的伙伴们,靠两只手起家,艰苦创业,在短短的六年时间里,使公司从原来一片空白的基础上,迅速发展成拥有六个合资企业和两个自办企业、固定资产4500万元、年工业总产值7000万元的工贸结合型综合性企业,成为深圳特区工业战线上的一支生力军.林利和同志也因其突出的贡献而先后荣获“全国能源工业劳动模范”和“中国煤炭工业优秀经理”的称号.林利和同志所取得的成功是令人羡慕的,但更引我们注目的,是他脚下那串凝结着成功者胆识与智慧的深深足迹.

阿斯匹林利弊谈

阿斯匹林1893年始用于临床,最初作为普通感冒解热止痛剂。几十年来,在多种疾病防治中发挥了巨大作用,已成为家喻户晓的药物。 有学者报道,阿斯匹林有增强免疫抑制剂的效果,对糖尿病和孕妇子痫也有良好的作用;目前治疗十分棘手的恶性肿瘤和艾滋病的实验研究,也取得了可喜成果。著名学者劳伦斯报道了他的研究成果。

Bamboo resources,utilization and ex-situ conservation in Xishuangbanna,South-eastern China

This paper describes the geographical distribution, utilization, cultural value and ex-situ conservation of bamboo resources in Xishuangbanna, Yunan Province, China. Sixty species of bamboo in 19 genera are recorded in Xishuangbanna. The area of natural bamboo forest is 14319 ha, accounting for 5.92% of whole area of Xishuangbanna. The abundant resource of bamboo plays an important role in the economics and culture of national minorities in Xishuangbanna. Xishuangbanna Tropic Botanic Garden, Chinese Academy of Sciences （CAS）, started to introduce bamboo species in 1961 and established the ex-situ conservation reserve （8 ha） of bamboo in 1981. Up to now, 211 species in 27 genera collected from tropic and sub-tropic of China and South-east Asia have been planted in the bamboo reserve, of which 11 species have bloomed and seeded, and their seeds were cultivated in Xishuangbanna Tropical Botanic Gardens, CAS, China.

Prevention and Utilization of Invasive Plants of Agriculture and Forestry in Guangdong Province

Guangdong has become a major＂window＂ for invasive plants, and the largest zone, where cross-border and intercontinental migration frequencies reach the peak. The invasive plants in Guangdong are dominated by Mikania micrantha, Eichhornia crassipes, Alternanthera philoxeroides, Eupatorium odoratum, and Wedelia trilobata. It is an important way for treating the invasive plants by exploring the prevention methods and making ful use of the characteristics of the invasive plants, and it is of great significance to prevent and utilize alien species in a scientific and effective way in order to control the invasive plants with minimal cost.

Spatial and temporal variations of soil moisture in three types of agroforestry boundaries in the Loess Plateau, China

Agroforestry is a ubiquitous landscape on the slopes in Loess Plateau, where soil moisture is a limiting factor for plant growth and development. The spatial and temporal characteristics of soil moisture were studied in three types of agroforestry boundaries： forest-grassland, forest-cropland and shelterbelt-cropland. The result shows that soil moisture content decreased with soil depth increasing from the surface to 110 cm. Soil moisture content differed significantly among the three boundaries all in the rainy season （July-September）, dry season （May-June） and spring （March-April）. The horizontal distribution of soil moisture in different soil layers in the three types of boundaries showed different patterns with line form, wave form, scoop form or ＂W＂ form. The distance of edge influence （DEI） of soil moisture in different types of landscape boundaries was estimated by variance analysis and multiple comparisons. In dry season the DEI in 0-10 cm soil layer was 0.4 H （H, average height of trees）, which ranged from 0.2 H in grassland or in cropland to 0.2 H in forest field for both forest-grassland and forest-cropland boundaries, and 0.7 H （ranged from 0.2 H in cropland to 0.5 H in forest field） for shelterbelt-cropland boundary. In rainy season the DEI at soil depth of 0-110 cm was 0.7 H for the three boundaries. The results indicated that agroforestry type should be carefully selected to maintain soil moisture in land management, especially in restoring degraded land in Loess Plateau.

Effects of freeze-thaw on soil nitrogen and phosphorus availability at the Keerqin Sandy Lands,China

A laboratory simulated freeze-thaw was conducted to determine the effects of freeze-thaw on soil nutrient availability in temperate semi-arid regions. Soil samples were collected from sandy soils （0-20 cm） of three typical ecosystems （grassland, Mongolian pine plantation and poplar plantation） in southeastern Keerqin Sandy Lands of China and subjected to freeze-thaw treatment （-12℃ for 10 days, then r 20℃ for 10 days） or incubated at constant temperature （20℃ for 20 days）. Concentrations of the soil NO3^--N, NH4^＋-N, NaHCO3 extractable inorganic P （LPi） and microbial biomass P （MBP） were determined on three occasions： at the start of the incubation, immediate post-thawing and at the 10th day post-thawing. The results showed that soil net nitrification and N mineralization rates at three sites were negatively affected by freeze-thaw treatment, and decreased by 50%-85% as compared to the control, of which the greatest decline occurred in the soil collected from poplar plantation. In contrast, the concentration of soil NH4^＋-N, NaHCO3 extractable inorganic P （LPi） and microbial biomass P were insignificantly influenced by freeze-thaw except that LPi and NH4^＋-N showed a slight increase immediate post-thawing. The effects of freeze-thaw on soil N transformation were related to soil biological processes and the relatively constant available P was ascribed to severe soil aridity.

圆机活法治顽痹

类风湿性关节炎中医称之为“顽痹”、“历节”等,临床治疗,颇感棘手,为难治病证之一。中国中医研究院西苑医院房定亚教授从医数十年,学验俱丰,擅长中医内科,尤精于类风湿性关节炎诊治。笔者有幸从师临证,目睹老师圆机活法,屡克顽痹。 通淋利尿,治顽痹肢肿身硬案 刘某某,男性,56岁。初诊1993年12月13日。主诉:全身关节僵硬疼痛5年,加重3个月。

Vertical variation and storage of nitrogen in an aquic brown soil under different land uses

The vertical variation and storage of nitrogen in the depth of 0-150 cm of an aquic brown soil were studied under 14 years of four land use patterns, i.e., paddy field, maize field, fallow field and woodland in Shenyang Experimental Station of Ecology, Chinese Academy of Sciences in November of 2003. The results showed that different land uses had different profile distributions of soil total nitrogen (STN), alkali N, ammonium (NH4+-N) and nitrate (NO3--N). The sequence of STN storage was woodland >maize field > fallow field > paddy field, while that of NO3--N content was maize field > paddy field > woodland > fallow field, suggesting the different root biomass and biological N cycling under various land uses. The STN storage in the depth of 0-100 cm of woodland averaged to 11.41 thm-1, being 1.65 and 1.25 times as much as that in paddy and maize fields, respec-tively, while there was no significant difference between maize and fallow fields. The comparatively higher amount of NO3--N in maize and paddy fields may be due to nitrogen fertilization and anthropogenic disturbance. Soil alkali N was significantly related with STN, and the correlation could be expressed by a linear regression model under each land use (R20.929, p<0.001). Such a correlation was slightly closer in nature (woodland and fallow field) than in agro ecosystems (paddy and maize fields). Heavy N fertilization induced an excess of crop need, and led to a comparatively higher amount of soil NO3--N in cultivated fields than in fallow field and woodland. It is suggested that agroforestry practices have the potential to make a significant contribution to both crop production and environment protection.

Summer-autumn habitat use by Galliformes in a primary forest,southeastern Tibet

Habitat use by Galliformes in an ornithologically unexplored region,a forest area in southeastern Tibet,was investigated during the summer and autumn periods of 1995.A total of seven species were recorded,most of which preferred habitats on south-facing slopes and avoided those on north-facing slopes where conditions were relatively humid.A hybrid population of White (Crossoptilon crossoptilon) versus Tibetan Eared-pheasants (C.harmani) was predominant among the Galliforme community,followed by Blood Pheasants (Ithaginis cruentus) and Chinese Grouse (Bonasa sewerzowi).A further investigation in 2001 showed that on account of little human activity in the distant primary forests,the birds suffered less of a threat from hunting and habitat disturbance.

企业供求

1.供彩照名片冲扩技术及设备 该技术不需照拍、印刷,即可制作带彩照的名片,版式、字体、图案随意设计变化,色泽艳丽,豪华气派,每盒成本仅10元,日可制20盒,又可冲扩1—24英寸彩照,每套2890元。备有样品,欢迎考察。 有意者可与100024北京869信箱356室林利联系。

Protection and Utilization of Cultural Landscape in a Forest Park in Ethnic Minority Region ——With a Case of Zhangjiajie

Presently, more and more attention is paid to cultural landscapes by peo-ple at travel ing, especial y for folk culture in ethnic minority regions where rich hu-man landscapes could be ful y made use of to improve landscape quality. In the research, cultural landscapes in Zhangjiajie National Forest Park were surveyed and evaluated to analyze characters of cultural utilization, as wel as problems existing in the Park. In addition, highlights were given to protection on cultural landscapes in a forest park construction, presentation of ethnic minority culture, and ful development of tourism products.

Impact of Land-use Patterns on Distributed Groundwater Recharge and Discharge——A Case Study of Western Jilin,China

The impact of land-use on distributed groundwater recharge and discharge in the western Jilin (WJ) was analyzed in this study. WJ is a transitional, semi-arid zone with a fragile, hydrological closed ecosystem in the Songhua River Basin (SRB). The research tool includes a seamlessly linked MODFLOW, WetSpass, the Seepage packages, and ArcGIS. The model calibration showed good agreement between simulated water table elevation and measured water table depths, while predicted groundwater discharge zones showed strong correlations with field occurrences of drainage systems and wetlands. Simulated averages for distributed recharge, water table elevation and groundwater drawdown were 377.42mm/yr, 194.43m, and 0.18m respectively. Forest vegetation showed the highest recharge, followed by ag- ricultural farmlands, while open-water and other drainage systems constituted groundwater exit zones. When present land-use conditions were compared with the hypothetical natural pre-development scenario, an overall loss of ground- water recharge (24.09mm/yr) was observed, which for the project area is 18.05×108m3. Groundwater abstraction seemed to be the cause of water table drawdown, especially in the immediate vicinities of the supply wells. An important issue of the findings was the ability of the hypothetical forest vegetation to protect, and hence sustain aquifer reserves and dependent ecosystems. The profound data capture capability of ArcGIS makes it particularly useful in spa- tio-temporal hydroecological modeling.

Tree wave migration across an elevation gradient in the Altai Mountains,Siberia

The phenomenon of tree waves （hedges and ribbons） formation within the alpine ecotone in Altai Mountains and its response to observed air temperature increase was considered. At the upper limit of tree growth Siberian pine （Pinus sibirica） forms hedges on windward slopes and ribbons on the leeward ones. Hedges were formed by prevailing winds and oriented along winds direction. Ribbons were formed by snow blowing and accumulating on the leeward slope and perpendicular to the prevailing winds, as well as to the elevation gradient. Hedges were always linked with microtopography features, whereas ribbons were not. Trees are migrating upward by waves and new ribbons and hedges are forming at or near tree line, whereas at lower elevations ribbons and hedges are being transformed into dosed forests. Time series of high-resolution satellite scenes （from 1968 to 2OLO） indicated an upslope shift in the position ribbons averaged 155＋26 m （or 3-7 m yr^-1） and crown closure increased （about 35%-90%）. The hedges advance was limited by poor regeneration establishment and was negligible. Regeneration within the ribbon zone was approximately 2.5 times （5060 vs 2120 ha^-1） higher then within the hedges zone. During the last four decades, Siberian pine in both hedges and ribbons strongly increased its growth increment, and recent tree growth rate for 50 year-old trees was about twice higher than those recorded for similarly-aged trees at the beginning of the 20^th century. Hedges and ribbons are phenomena that are widespread within the southern and northern Siberian Mountains.

Soil N Pools and Transformation Rates Under Different Land Uses in a Subalpine Forest-Grassland Ecotone

Soil nitrogen pools (NP), denitrification (DN), gross nitrification (GN), N2O and CO2 flux rates with their responses to temperature increases were determined under five different land uses and managements in a subalpine forest-grassland ecotone of the eastern Tibetan Plateau. Land uses consisted of 1) sparse woodland, 2) shrub-land, 3) natural pasture, 4)fenced pasture, and 5) tilled pasture mimicking a gradient degenerating ecosystem under grazing impacts. The NO3--N content was higher than the NH4+-N content. Comparing tilled pasture with fenced pasture showed that higher intensive management (tillage) led to a significant decrease of soil organic matter (SOM) (P ＜ 0.05) in the soils, which was in contrast to the significant increases (P ＜0.05) of DN, GN, N2O and CO2 flux rates. GN (excluding tilled pasture) and CO2 flux rates increased with a temperature rise, but DN and N2O flux rates normally reached their maximum values at 12-14 ℃ with tilled pasture (the highest management intensity) being very sensitive to temperature increases. There was a difference between net nitrification and GN, with GN being a betterindicator of soil nitrification.

Ischemic colitis during interferon-ribavirin therapy for chronic hepatitis C:A case report

Ischemic colitis is a rare complication of interferon administration.Only 9 cases in 6 reports have been described to-date.This report describes a case of ischemic colitis during pegylated interferon and ribavirin treatment for chronic hepatitis C,and includes a review of the relevant literature.A 48-year-old woman was treated with pegylated interferon-2a and ribavirin for chronic hepatitis C,genotype Ib.After 19 wk of treatment,the patient complained of severe afebrile abdominal pain with hematochezia.Vital signs were stable and serum white blood cell count was within the normal range.Abdominal computed tomography showed diffuse colonic wall thickening from the splenic flexure to the proximal sigmoid colon,which is the most vulnerable area for the development of ischemic colitis.Colonoscopy revealed an acute mucosal hyperemic change,with edema and ulcerations extending from the proximal descending colon to the sigmoid colon.Colonic mucosal biopsy revealed acute exudative colitis.Polymerase chain reaction and culture for Mycobacterium tuberculosis were negative and the cultures for cytomegalovirus,Salmonella and Shigella species were negative.After discontinuation of interferon and ribavirin therapy,abdominal pain and hematochezia subsided and,following colonoscopy showed improvement of the mucosal ulcerations.Ischemic colitis cases during interferon therapy in patients with chronic hepatitis C reported so far have all involved the descending colon.Ischemic colitis is a rarely encountered complication of interferon administration in patients with chronic hepatitis C and should be considered when a patient complains of abdominal pain and hematochezia.

Quasispecies evolution in NS5A region of hepatitis C virus genotype 1b during interferon or combined interferon-ribavirin therapy

AIM: To evaluate the implication of substitutions in the hepatitis C virus (HCV) non-structural 5A (NS5A) protein in the resistance of HCV during mono-interferon (IFN) or combined IFN-ribavirin (IFN-R) therapy. Although NS5A has been reported to interact with the HCV RNA- dependent RNA polymerase, NS5B, as well as with many cellular proteins, the function of NS5A in the life cycle of HCV remains unclear. METHODS: HCV quasispecies were studied by clon- ing and sequencing of sequential isolates from patients infected by HCV genotype 1b. Patients were treated by IFN-α2b for 3 mo followed by IFN-α2b alone or com- bined IFN-R therapy for 9 additional months. Patients were categorized intro two groups based on their re- sponse to the treatments: 7 with sustained virological re- sponse (SVR) (quasispecies = 150) and 3 non-respond- ers (NR) to IFN-R (quasispecies = 106). RESULTS: Prior to treatment, SVR patients displayed a lower complexity of quasispecies than NR patients. Most patients had a decrease in the complexity of quasispe- cies during therapy. Analysis of amino acids substitu- tions showed that the degree of the complexity of the interferon sensitivity-determining region (ISDR) and the V3 domain of NS5A protein was able to discriminate thetwo groups of patients. Moreover, SVR patients displayed more variability in the NS5A region than NR patients. CONCLUSION: These results suggest that detailed mo- lecular analysis of the NS5A region may be important for understanding its function in IFN response during HCV 1b infection.

Land Use Structure in Wuhai City on Basis of Ecological Green Equivalence

The paper took Wuhai District as an example, bases on the contrast be-tween the land use condition in 2005 and 2010, and applied the ecological green equivalence to establish a mathematic model of ecological optimization of land use structure, to establish the ecology green equivalent mathematical model and survey the value of region green equivalent, and then assess the ecological environment situation. The results show that the ecological environment has been deteriorated in Wuhai from 2005 to 2010, so the ecological environment was poor. In order to in-crease eco-efficiency of land use, garden, urban green space and woodland area should be raised in the optimization program.

Long-term outcome of chronic hepatitis C patients with sustained virological response to peginterferon plus ribavirin

AIM: To assess the clinical, biochemical and virological long-term outcome in chronic hepatitis C (CHC) patients with a sustained virological response (SVR) after peginterferon (PEG-IFN) plus ribavirin combination therapy. METHODS: One hundred and fifty three patients with a SVR after treatment with PEG-IFN plus ribavirin were included in a 5-year follow-up study in a single Spanish center, based on standard clinical practice. Clinical anamnesis, biochemical analysis, hepatitis C virus RNA and alpha-fetoprotein measurement, ultrasonography and transient elastography were performed annually. RESULTS: The mean follow-up period of the 153 patients was 76 ± 13 mo after they obtained a SVR. Five patients (3.26%) presented with cirrhosis before treatment and 116 (75.8%) had genotype 1. No patient showed evidence of hepatic decompensation. One patient (0.65%) developed a hepatocellular carcinoma at month 30 after achieving SVR. There were no virological relapses during this follow-up period. Persistently elevated alanine aminotransferase was found in only one patient (0.65%). At the end of the 5-year follow-up, the mean value of transient elastography was 7 ± 4.3 kPa (F1). There were no deaths and no other tumors. CONCLUSION: The long-term outcome of 153 CHC patients with SVR to PEG-IFN plus ribavirin was good. No evidence of a virological relapse was seen. One patient (0.65%) developed a hepatocellular carcinoma.

Impact of ribavirin dose on retreatment of chronic hepatitis C patients

AIM: To study the efficacy and factors associated with a sustained virological response (SVR) in chronic hepatitis C (CHC) relapsing patients. METHODS: Out of 1228 CHC patients treated with pegylated interferon (PEG-IFN) and ribavirin (RBV), 165 (13%) had a relapse. Among these, 62 patients were retreated with PEG-IFN-2a or-2b and RBV. Clinical, biological, virological and histological data were collected. Initial doses and treatment modifications were recorded. The efficacy of retreatment and predictive factors for SVR were analyzed. RESULTS: An SVR was achieved in 42% of patients. SVR was higher in young (< 50 years) (61%) than old patients (27%) (P = 0.007), and in genotype 2 or 3 (57%) than in genotype 1 or 4 (28%) patients (P = 0.023). Prolonging therapy for at least 24 wk more than the previous course was associated with higher SVR rates (53% vs 28%, P = 0.04). Also, a better SVR rate was observed with RBV dose/body weight > 15.2 mg/kg per day (70% vs 35%, P = 0.04). In logistic regression, predictors of a response were age (P = 0.018), genotype (P = 0.048) and initial RBV dose/body weight (P = 0.022). None of the patients without a complete early virological response achieved an SVR (negative predictive value = 100%). CONCLUSION: Retreatment with PEG-IFN/RBV is effective in genotype 2 or 3 relapsers, especially in young patients. A high dose of RBV seems to be important for the retreatment response.