According to the relationship between Toona sinensis Roem stand volume,productivity and forest age,site conditions,stand density and other factors,through selecting 8 representative cities or counties,using standard i...According to the relationship between Toona sinensis Roem stand volume,productivity and forest age,site conditions,stand density and other factors,through selecting 8 representative cities or counties,using standard investigation and stem analysis method,this paper makes relatively systematic research about the Toona sinensis Roem plantation accumulation,productivity,and the relationship between them and site conditions.Through comparative analysis indicators of multiple site conditions,this paper expects to give a more comprehensive picture about the source of accumulation and productivity difference.展开更多
Objective Pelvic inflammatory disease(PID)is one of the most common gynaecological diseases.Here,this thesis aims to investigate the therapeutic effects of Prunella vulgaris L.oil on the PID by using metabolomics base...Objective Pelvic inflammatory disease(PID)is one of the most common gynaecological diseases.Here,this thesis aims to investigate the therapeutic effects of Prunella vulgaris L.oil on the PID by using metabolomics based on gas chromatographymass spectrometry(GC-MS)to address this challenge.Methods First,measurements of pro-inflammatory cytokines and histological analysis of the uterus were conducted to validate the successful generation of a PID rat model.Furthermore,the volatile oil from Prunella vulgaris L.was administered to treat PID rats.Serum samples were collected before and after treatment and analyzed by GC-MS to generate metabolite profiles for each sample.The information generated from the qualitative and quantitative analysis of these metabolites was applied to distinguish between the PID model and normal control groups.Results Some metabolites,such as acetic acid,succinic acid,glyceric acid,(R*,S*)-3,4-dihydroxybutanoic acid,3-hydroxyphenylacetic acid,D-ribose and myo-inositol showed a higher contribution in the classification model;thus,they can be considered as potential biomarkers.Furthermore,the therapeutic effect of the volatile oil extracted from Prunella vulgaris L.could also be visualized using GC-MS-based metabolomics.Conclusions The results show that metabolomics studies are invaluable for disease diagnosis and therapeutic effect estimation.展开更多
A regional ocean atmosphere coupled model (ROAM) is developed through coupler OASIS3,and is composed of regional climate model RegCM3 and CREM (Climate version of Regional Eta Model) as its atmospheric component and o...A regional ocean atmosphere coupled model (ROAM) is developed through coupler OASIS3,and is composed of regional climate model RegCM3 and CREM (Climate version of Regional Eta Model) as its atmospheric component and of a revised Princeton ocean model (POM2000) as its oceanic component.The performance of the ROAM over the western North Pacific summer monsoon region is assessed by the case simulation of warm season in 1998.Impacts of different atmospheric model components on the performance of ROAM are investigated.Compared with stand-alone simulation,CREM (RegCM3) produces more (or less) rainfall over ocean area with inclusion of the air-sea coupling.Different biases of rainfall are caused by the different biases of SST derived from the coupled simulation.Warm (or cold) SST bias simulated by CREM_CPL (RegCM3_CPL) increases (or decreases) the evaporation at sea surface,then increases (or decreases) the rainfall over ocean.The analyses suggest that the biases of vertical profile of temperature and specific humidity in stand-alone simulations may be responsible for the SST biases in regional coupled simulations.Compared with reanalysis data,the warmer (or colder) and moister (or dryer) lower troposphere simulated in CREM (RegCM3) produces less (or more) sea surface latent heat flux.Meanwhile,the more unstable (or stable) lower troposphere produces less (or more) cloudiness at low-level,which increases (or decreases) the solar radiation reaching on the sea surface.CREM (RegCM3) forced by observed SST overestimates (or underestimates) the sea surface net heat flux,implying a potential warm (or cold) heat source.After coupling with POM2000,the warm (or cold) heat source would further increase (or decrease) the SST.The biases of vertical profile of temperature and specific humidity may be ascribed to the different representation of cumulus convection in atmospheric models.展开更多
文摘According to the relationship between Toona sinensis Roem stand volume,productivity and forest age,site conditions,stand density and other factors,through selecting 8 representative cities or counties,using standard investigation and stem analysis method,this paper makes relatively systematic research about the Toona sinensis Roem plantation accumulation,productivity,and the relationship between them and site conditions.Through comparative analysis indicators of multiple site conditions,this paper expects to give a more comprehensive picture about the source of accumulation and productivity difference.
基金We thank for the funding support from the National Natural Science Foundation of China(No.81503041)Natural Science Foundation of Hunan Province(No.2017JJ4045)Changsha Science and Technology Project(No.kq1701073).
文摘Objective Pelvic inflammatory disease(PID)is one of the most common gynaecological diseases.Here,this thesis aims to investigate the therapeutic effects of Prunella vulgaris L.oil on the PID by using metabolomics based on gas chromatographymass spectrometry(GC-MS)to address this challenge.Methods First,measurements of pro-inflammatory cytokines and histological analysis of the uterus were conducted to validate the successful generation of a PID rat model.Furthermore,the volatile oil from Prunella vulgaris L.was administered to treat PID rats.Serum samples were collected before and after treatment and analyzed by GC-MS to generate metabolite profiles for each sample.The information generated from the qualitative and quantitative analysis of these metabolites was applied to distinguish between the PID model and normal control groups.Results Some metabolites,such as acetic acid,succinic acid,glyceric acid,(R*,S*)-3,4-dihydroxybutanoic acid,3-hydroxyphenylacetic acid,D-ribose and myo-inositol showed a higher contribution in the classification model;thus,they can be considered as potential biomarkers.Furthermore,the therapeutic effect of the volatile oil extracted from Prunella vulgaris L.could also be visualized using GC-MS-based metabolomics.Conclusions The results show that metabolomics studies are invaluable for disease diagnosis and therapeutic effect estimation.
基金supported by the Ocean Projects of Public Science and Technology Research Funds (Grant No. 201105019-3)
文摘A regional ocean atmosphere coupled model (ROAM) is developed through coupler OASIS3,and is composed of regional climate model RegCM3 and CREM (Climate version of Regional Eta Model) as its atmospheric component and of a revised Princeton ocean model (POM2000) as its oceanic component.The performance of the ROAM over the western North Pacific summer monsoon region is assessed by the case simulation of warm season in 1998.Impacts of different atmospheric model components on the performance of ROAM are investigated.Compared with stand-alone simulation,CREM (RegCM3) produces more (or less) rainfall over ocean area with inclusion of the air-sea coupling.Different biases of rainfall are caused by the different biases of SST derived from the coupled simulation.Warm (or cold) SST bias simulated by CREM_CPL (RegCM3_CPL) increases (or decreases) the evaporation at sea surface,then increases (or decreases) the rainfall over ocean.The analyses suggest that the biases of vertical profile of temperature and specific humidity in stand-alone simulations may be responsible for the SST biases in regional coupled simulations.Compared with reanalysis data,the warmer (or colder) and moister (or dryer) lower troposphere simulated in CREM (RegCM3) produces less (or more) sea surface latent heat flux.Meanwhile,the more unstable (or stable) lower troposphere produces less (or more) cloudiness at low-level,which increases (or decreases) the solar radiation reaching on the sea surface.CREM (RegCM3) forced by observed SST overestimates (or underestimates) the sea surface net heat flux,implying a potential warm (or cold) heat source.After coupling with POM2000,the warm (or cold) heat source would further increase (or decrease) the SST.The biases of vertical profile of temperature and specific humidity may be ascribed to the different representation of cumulus convection in atmospheric models.
