AIM： To evaluate whether adding azithromycin to firstline Helicobacter pylori （H pylorl） eradication improved eradication and reduced side effects. METHODS： Eligible articles were identified by searches of electro...AIM： To evaluate whether adding azithromycin to firstline Helicobacter pylori （H pylorl） eradication improved eradication and reduced side effects. METHODS： Eligible articles were identified by searches of electronic databases. We included all randomized trials that compared azithromycin-containing with standard triple-therapy regimens for first-line treatment of H pylori infection. Statistical analysis was performed with Review Manager 5.0.10. Sub-analyses were also performed. RESULTS： We identified 14 randomized trials （1431 patients）. Pooled Hpylori eradication rates were 72.01% （95% CI： 58.09%-85.93%） and 69.78% （95% CI： 66.47%-73.09%） for patients with or without azithromycin by intention-to-treat analysis, and the odds ratio （OR） was 1.17 （95% CI： 0.64-2.14）. The occurrence of side effects differed significantly and was 15.81% （95% CI： 12.50%-19.12%） and 25.20% （95% CI： 21.44%-28.96%） for treatment with or without azithromycin, respectively, and the summary OR was 0.58 （95% CI： 0.41-0.82）. Furthermore, the azithromycin-containing group had a lower occurrence of diarrhea, nausea and taste disturbance. CONCLUSION： Our review suggests that azithromycincontaining triple-therapy regimens could be equally effective in eradication of Hpylori compared with standard first-line triple-therapy regimens.展开更多
This study was conducted to evaluate the performance of the four stem taper models on Camellia japonica in Jeju Island, Korea using fit statistics and lack-of-fit statistics. The five statistical criteria that were us...This study was conducted to evaluate the performance of the four stem taper models on Camellia japonica in Jeju Island, Korea using fit statistics and lack-of-fit statistics. The five statistical criteria that were used in this study were standard error of estimate(SEE), mean bias( E), absolute mean difference(AMD), coefficient of determination(R2), and root mean square error(RMSE). Results showed that the Kozak model 02 stem taper had the best performance in all fit statistics(SEE: 3.4708, E : 0.0040 cm, AMD : 0.9060 cm, R2 : 0.9870, and RMSE : 1.2545). On the other hand, Max and Burkhart stem taper model had the poorest performance in each statistical criterion(SEE: 4.2121, E : 0.2520 cm, AMD : 1.1300 cm, R2 : 0.9805, and RMSE: 1.5317). For the lack-of-fit statistics, the Kozak model 02 also provided the best performance having the best AMD in most of the relative height classes for diameter outside bark prediction and in most of the DBH classes for total volume prediction while Max and Burkhart had the poorest performance. These stem taper equations could help forest managers to better estimate the diameter outside bark at any given height, merchantable stem volumes and total stem volumes of the standing trees of Camellia japonica in the forests of Jeju Island, Korea.展开更多
Objective:To evaluate the effect of modified surgical techniques on hemostasis used in aortic root replacement with a composite graft(Bentall procedure).Methods:Data on 15 patients who underwent Bentall procedure duri...Objective:To evaluate the effect of modified surgical techniques on hemostasis used in aortic root replacement with a composite graft(Bentall procedure).Methods:Data on 15 patients who underwent Bentall procedure during 2005 to 2007 were analyzed.The first 5 patients(Group 1) received the standard procedure.Then next 10 patients(Group 2) received the modified procedure.Techniques including "tandem suture line","endo-button buttress","sandwich anastomosis" and "left ventricle filling" were added to the standard procedure.Perioperative bleeding and the volume of blood transfusion required were compared to estimate hemostasis in different groups.Results:Between groups 1 and 2,a significant difference was found in postoperative bleeding [(2193±383) ml vs(1012±258) ml,respectively;P<0.05] and in volume of blood transfusion required [(7242±1416) ml vs(2520±708) ml,respectively;P<0.05].Conclusion:The modified surgical techniques used in our study are effective in the improvement of the hemostasis in Bentall procedure.展开更多
Based on daily mean temperature records from 1961 to 2007 at 20 meteorological sites in Southwest Yunnan, and the surface temperature simulated by IPCC AR4 Climate Models, a quantitative examination was undertaken int...Based on daily mean temperature records from 1961 to 2007 at 20 meteorological sites in Southwest Yunnan, and the surface temperature simulated by IPCC AR4 Climate Models, a quantitative examination was undertaken into the characteristics of multi-timescale temperature （AMT, DMT and WMT） variation in Southwest Yunnan. The simulation abilities of the models were also evaluated with the normalized root mean square error （NRMSE） and Mann-Kendal test statistic methods. Temperatures show remarkable increasing trend from 1961 to 2007, with the Mann-Kendall test statistic passing 95% confidence verification. The result of the NRMSE analysis shows that the simulated temperature anomaly variations are more similar to observed ones especially for AMT and DMT, and the projected result （anomalies） of IPCC AR4 climate models can be used for predicting the trends in multi-timescale temperature variation in Southwest Yunnan in the next 40 years under the three emission scenarios, which has better simulating effect on AMT and DMT than WMT. Over the next 40 years the temperature will continue to rise, with annual mean temperature showing a more remarkable rising trend than that of the dry and wet seasons. Temperature anomalies exhibit different increasing rates under different emission scenarios： During the 2020s the rising rates of multi-timescale temperature anomalies in a high greenhouse gases emissions scenario （SRESA2） are smaller than those under a low emission scenario （SRESB1）. Except that, the rate of increase in temperature anomalies are the highest in the intermediate emissions scenario （SRESA1B）, followed by those in SRESA2, and those in low emissions scenario （SRESB1） are the lowest. The reason of different simulating effects on WMT from AMT and DMT was also discussed.展开更多
OBJECTIVE： To determine the effectiveness of modified Sanhuang Xiexin Tang （SHXXT） plus additional herbs （MSAH） combined with ＂standard tri- ple therapy＂ for eradication of Helicobacter pylori （H. pylori） and...OBJECTIVE： To determine the effectiveness of modified Sanhuang Xiexin Tang （SHXXT） plus additional herbs （MSAH） combined with ＂standard tri- ple therapy＂ for eradication of Helicobacter pylori （H. pylori） and amelioration of related symptoms in comparison with standard triple and standard quadruple therapies. METHODS： From October 2015 to May 2016, we recruited patients with dyspepsia symptoms con- firmed to have H. pylori infection by the ^13C urea breath test in our outpatient clinic. Patients were randomly divided into three treatment groups： Nexium standard triple therapy （group A, EAC）, Nexium standard quadruple therapy （group B, EBAC）, or Nexium standard triple therapy combined with MSAH （group C; EAC＋MSAH）. Comparisons of H. pylori eradication and symptom amelioration rates were made among the three groups at 2 or 6 weeks after group assignment. RESULTS： There was no difference in H. pylori eradication rates between groups B （EBAC） and C （EAC＋ MSAH） （P = 0.486）, and eradication rates in groups B and C were significantly higher than that in group A （EAC） （P Av, e = 0.001; P AvsC= 0.003）. There was no difference in the total symptom score among the groups before treatment. In all groups, the total symptom scores after treatment （2 or 6 weeks after group assignment） were significantly lower than those before treatment （P 〈 0.001 for all）. However, group C （EAC ＋ MSAH） demonstrated superior total symptom scores and symptom amelioration rates than groups A （EAC） and B （EBAC）. Group B also demonstrated better scores and rates than group A. There was no difference in symptom amelioration rates at 2 and 6 weeks within each group. CONCLUSION： There is no difference between MSAH combined with standard triple therapy and standard quadruple therapy containing bismuth with regard to H. pylori eradication rate. However, MSAH combined with standard triple therapy has a higher symptom amelioration rate and therefore appears to be an ideal treatment scheme for H. pyIori eradication.展开更多
文摘AIM： To evaluate whether adding azithromycin to firstline Helicobacter pylori （H pylorl） eradication improved eradication and reduced side effects. METHODS： Eligible articles were identified by searches of electronic databases. We included all randomized trials that compared azithromycin-containing with standard triple-therapy regimens for first-line treatment of H pylori infection. Statistical analysis was performed with Review Manager 5.0.10. Sub-analyses were also performed. RESULTS： We identified 14 randomized trials （1431 patients）. Pooled Hpylori eradication rates were 72.01% （95% CI： 58.09%-85.93%） and 69.78% （95% CI： 66.47%-73.09%） for patients with or without azithromycin by intention-to-treat analysis, and the odds ratio （OR） was 1.17 （95% CI： 0.64-2.14）. The occurrence of side effects differed significantly and was 15.81% （95% CI： 12.50%-19.12%） and 25.20% （95% CI： 21.44%-28.96%） for treatment with or without azithromycin, respectively, and the summary OR was 0.58 （95% CI： 0.41-0.82）. Furthermore, the azithromycin-containing group had a lower occurrence of diarrhea, nausea and taste disturbance. CONCLUSION： Our review suggests that azithromycincontaining triple-therapy regimens could be equally effective in eradication of Hpylori compared with standard first-line triple-therapy regimens.
基金support of the Warm Temperate and Subtropical Forest Research Center, Korea Forest Research Institute
文摘This study was conducted to evaluate the performance of the four stem taper models on Camellia japonica in Jeju Island, Korea using fit statistics and lack-of-fit statistics. The five statistical criteria that were used in this study were standard error of estimate(SEE), mean bias( E), absolute mean difference(AMD), coefficient of determination(R2), and root mean square error(RMSE). Results showed that the Kozak model 02 stem taper had the best performance in all fit statistics(SEE: 3.4708, E : 0.0040 cm, AMD : 0.9060 cm, R2 : 0.9870, and RMSE : 1.2545). On the other hand, Max and Burkhart stem taper model had the poorest performance in each statistical criterion(SEE: 4.2121, E : 0.2520 cm, AMD : 1.1300 cm, R2 : 0.9805, and RMSE: 1.5317). For the lack-of-fit statistics, the Kozak model 02 also provided the best performance having the best AMD in most of the relative height classes for diameter outside bark prediction and in most of the DBH classes for total volume prediction while Max and Burkhart had the poorest performance. These stem taper equations could help forest managers to better estimate the diameter outside bark at any given height, merchantable stem volumes and total stem volumes of the standing trees of Camellia japonica in the forests of Jeju Island, Korea.
文摘Objective:To evaluate the effect of modified surgical techniques on hemostasis used in aortic root replacement with a composite graft(Bentall procedure).Methods:Data on 15 patients who underwent Bentall procedure during 2005 to 2007 were analyzed.The first 5 patients(Group 1) received the standard procedure.Then next 10 patients(Group 2) received the modified procedure.Techniques including "tandem suture line","endo-button buttress","sandwich anastomosis" and "left ventricle filling" were added to the standard procedure.Perioperative bleeding and the volume of blood transfusion required were compared to estimate hemostasis in different groups.Results:Between groups 1 and 2,a significant difference was found in postoperative bleeding [(2193±383) ml vs(1012±258) ml,respectively;P<0.05] and in volume of blood transfusion required [(7242±1416) ml vs(2520±708) ml,respectively;P<0.05].Conclusion:The modified surgical techniques used in our study are effective in the improvement of the hemostasis in Bentall procedure.
基金National Natural Science Foundation of China (40901050), National Basic Research Program of China (No. 2012CB955903)Scientific Research Fund Project of Yunnan Provincial Department of Education (No. 09Y0284, "Technology Research of Adaptation and Mitigation to Yunnan Climate Change")
文摘Based on daily mean temperature records from 1961 to 2007 at 20 meteorological sites in Southwest Yunnan, and the surface temperature simulated by IPCC AR4 Climate Models, a quantitative examination was undertaken into the characteristics of multi-timescale temperature （AMT, DMT and WMT） variation in Southwest Yunnan. The simulation abilities of the models were also evaluated with the normalized root mean square error （NRMSE） and Mann-Kendal test statistic methods. Temperatures show remarkable increasing trend from 1961 to 2007, with the Mann-Kendall test statistic passing 95% confidence verification. The result of the NRMSE analysis shows that the simulated temperature anomaly variations are more similar to observed ones especially for AMT and DMT, and the projected result （anomalies） of IPCC AR4 climate models can be used for predicting the trends in multi-timescale temperature variation in Southwest Yunnan in the next 40 years under the three emission scenarios, which has better simulating effect on AMT and DMT than WMT. Over the next 40 years the temperature will continue to rise, with annual mean temperature showing a more remarkable rising trend than that of the dry and wet seasons. Temperature anomalies exhibit different increasing rates under different emission scenarios： During the 2020s the rising rates of multi-timescale temperature anomalies in a high greenhouse gases emissions scenario （SRESA2） are smaller than those under a low emission scenario （SRESB1）. Except that, the rate of increase in temperature anomalies are the highest in the intermediate emissions scenario （SRESA1B）, followed by those in SRESA2, and those in low emissions scenario （SRESB1） are the lowest. The reason of different simulating effects on WMT from AMT and DMT was also discussed.
文摘OBJECTIVE： To determine the effectiveness of modified Sanhuang Xiexin Tang （SHXXT） plus additional herbs （MSAH） combined with ＂standard tri- ple therapy＂ for eradication of Helicobacter pylori （H. pylori） and amelioration of related symptoms in comparison with standard triple and standard quadruple therapies. METHODS： From October 2015 to May 2016, we recruited patients with dyspepsia symptoms con- firmed to have H. pylori infection by the ^13C urea breath test in our outpatient clinic. Patients were randomly divided into three treatment groups： Nexium standard triple therapy （group A, EAC）, Nexium standard quadruple therapy （group B, EBAC）, or Nexium standard triple therapy combined with MSAH （group C; EAC＋MSAH）. Comparisons of H. pylori eradication and symptom amelioration rates were made among the three groups at 2 or 6 weeks after group assignment. RESULTS： There was no difference in H. pylori eradication rates between groups B （EBAC） and C （EAC＋ MSAH） （P = 0.486）, and eradication rates in groups B and C were significantly higher than that in group A （EAC） （P Av, e = 0.001; P AvsC= 0.003）. There was no difference in the total symptom score among the groups before treatment. In all groups, the total symptom scores after treatment （2 or 6 weeks after group assignment） were significantly lower than those before treatment （P 〈 0.001 for all）. However, group C （EAC ＋ MSAH） demonstrated superior total symptom scores and symptom amelioration rates than groups A （EAC） and B （EBAC）. Group B also demonstrated better scores and rates than group A. There was no difference in symptom amelioration rates at 2 and 6 weeks within each group. CONCLUSION： There is no difference between MSAH combined with standard triple therapy and standard quadruple therapy containing bismuth with regard to H. pylori eradication rate. However, MSAH combined with standard triple therapy has a higher symptom amelioration rate and therefore appears to be an ideal treatment scheme for H. pyIori eradication.
