To prevent a vehicle from departing the lane in assistant or automatic steering, real-time vision-based detection of lane is studied. The system architecture, detecting principle and lane model are described. Then the...To prevent a vehicle from departing the lane in assistant or automatic steering, real-time vision-based detection of lane is studied. The system architecture, detecting principle and lane model are described. Then the detecting algorithm of the lane image is discussed in detail. In this algorithm, several proper sub-windows in one image are first selected as the processing regions. To every sub-window, by means of such steps as appropriate pre-processing, edge detection and Hough transform, etc., the lane description features are extracted. Experimental results reveal that this detection method is of good real-time, high recognition reliability and strong robustness, etc., which can provide the decision-making foundation for the following automatic or assistant steering to some extent.展开更多
AIM:To characterize the differentially expressed gene profiles in livers from biliary atresia (BA) patients including,ascertain genes,functional categories and pathways that play a central role in the pathogenesis of ...AIM:To characterize the differentially expressed gene profiles in livers from biliary atresia (BA) patients including,ascertain genes,functional categories and pathways that play a central role in the pathogenesis of BA,and identify the novel prognostic markers for BA.METHODS:Liver tissue samples from control patients,neonatal cholestasis patients,and BA patients at the age of < 60 d,60-90 d,and > 90 d were pooled for DNA microarray analysis.Bioinformatics analysis was performed using,series test cluster of gene ontology,and Pathway-Finder software.Reverse-transcription polymerase chain reaction was performed to confirm changes in selected genes.Relation between RRAS gene expression and prognosis of 40 BA patients was analyzed in a 2-year follow-up study.RESULTS:The 4 identified significant gene expression profiles could confidently separate BA liver tissue from normal and other diseased liver tissues.The included genes were mainly involved in inflammation response and reconstruction of cellular matrix.The significant pathways associated with BA were primarily involved in autoimmune response,activation of T lymphocytes and its related cytokines.The RRAS,POMC,SLC26A6 and STX3 genes were important regulatory modules in pathogenesis of BA.The expression of RRAS was negatively correlated with the elimination rate of jaundice and positively correlated with the occurrence rate of cholangitis.CONCLUSION:Autoimmune response mediated by T lymphocytes may play a vital role in the pathogenesis of BA.The RRAS gene is an important regulatory module in the pathogenesis of BA,which may serve as a novel prognostic marker for BA.展开更多
文摘To prevent a vehicle from departing the lane in assistant or automatic steering, real-time vision-based detection of lane is studied. The system architecture, detecting principle and lane model are described. Then the detecting algorithm of the lane image is discussed in detail. In this algorithm, several proper sub-windows in one image are first selected as the processing regions. To every sub-window, by means of such steps as appropriate pre-processing, edge detection and Hough transform, etc., the lane description features are extracted. Experimental results reveal that this detection method is of good real-time, high recognition reliability and strong robustness, etc., which can provide the decision-making foundation for the following automatic or assistant steering to some extent.
基金Supported by National Natural Science Foundation of China,No.30973139
文摘AIM:To characterize the differentially expressed gene profiles in livers from biliary atresia (BA) patients including,ascertain genes,functional categories and pathways that play a central role in the pathogenesis of BA,and identify the novel prognostic markers for BA.METHODS:Liver tissue samples from control patients,neonatal cholestasis patients,and BA patients at the age of < 60 d,60-90 d,and > 90 d were pooled for DNA microarray analysis.Bioinformatics analysis was performed using,series test cluster of gene ontology,and Pathway-Finder software.Reverse-transcription polymerase chain reaction was performed to confirm changes in selected genes.Relation between RRAS gene expression and prognosis of 40 BA patients was analyzed in a 2-year follow-up study.RESULTS:The 4 identified significant gene expression profiles could confidently separate BA liver tissue from normal and other diseased liver tissues.The included genes were mainly involved in inflammation response and reconstruction of cellular matrix.The significant pathways associated with BA were primarily involved in autoimmune response,activation of T lymphocytes and its related cytokines.The RRAS,POMC,SLC26A6 and STX3 genes were important regulatory modules in pathogenesis of BA.The expression of RRAS was negatively correlated with the elimination rate of jaundice and positively correlated with the occurrence rate of cholangitis.CONCLUSION:Autoimmune response mediated by T lymphocytes may play a vital role in the pathogenesis of BA.The RRAS gene is an important regulatory module in the pathogenesis of BA,which may serve as a novel prognostic marker for BA.
