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双靶标高敏HBV DNA检测技术在HBeAg阴性患者临床诊断中应用 被引量:2
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作者 冯磊 《分子诊断与治疗杂志》 2019年第5期369-373,共5页
目的对比双靶标高敏和普敏2种方法在血清乙型肝炎临床诊断中的应用价值。方法针对180例血清乙型肝炎e抗原(HBeAg)阴性患者,分别采用双靶标高敏和普敏方法进行血清HBV DNA定量分析,并对HBV DNA水平和HBV感染相关性进行分析。结果180例血... 目的对比双靶标高敏和普敏2种方法在血清乙型肝炎临床诊断中的应用价值。方法针对180例血清乙型肝炎e抗原(HBeAg)阴性患者,分别采用双靶标高敏和普敏方法进行血清HBV DNA定量分析,并对HBV DNA水平和HBV感染相关性进行分析。结果180例血清HBeAg阴性患者中,双靶标高敏法检出阳性103例,阴性77例,阳性检出率57.2%;普敏法检测出阳性35例,阴性145例,阳性检出率19.4%。双靶标高敏法阳性检出率显著高于普敏法,差异具有统计学意义(P<0.001)。临床诊断慢性乙型肝炎患者HBV DNA检出率显著高于临床诊断非活动性HBsAg携带者,差异具有统计学意义(P<0.01)。结论双靶标高敏法用于HBV DNA定量检测的灵敏度高于普敏法,更有助于医生临床诊断,并对患者的治疗、耐药预测及隐匿性肝炎的检出具有重要意义。 展开更多
关键词 双靶标高敏乙肝检测方法 普敏检测 HBeAg(-)
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Adaptive moving target detection algorithm based on Gaussian mixture model 被引量:1
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作者 杨欣 刘加 +1 位作者 费树岷 周大可 《Journal of Southeast University(English Edition)》 EI CAS 2013年第4期379-383,共5页
In order to enhance the reliability of the moving target detection, an adaptive moving target detection algorithm based on the Gaussian mixture model is proposed. This algorithm employs Gaussian mixture distributions ... In order to enhance the reliability of the moving target detection, an adaptive moving target detection algorithm based on the Gaussian mixture model is proposed. This algorithm employs Gaussian mixture distributions in modeling the background of each pixel. As a result, the number of Gaussian distributions is not fixed but adaptively changes with the change of the pixel value frequency. The pixels of the difference image are divided into two parts according to their values. Then the two parts are separately segmented by the adaptive threshold, and finally the foreground image is obtained. The shadow elimination method based on morphological reconstruction is introduced to improve the performance of foreground image's segmentation. Experimental results show that the proposed algorithm can quickly and accurately build the background model and it is more robust in different real scenes. 展开更多
关键词 moving target detection Gaussian mixture model background subtraction adaptive method
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住宅楼建设工程的测量监理
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作者 许志文 《安徽建筑》 2001年第1期107-108,共2页
住宅楼建设工程的监理工作中,测量监理是其对质量、进度、投资控制的重要手段,测量监理工作贯穿住宅楼建设工程的每个阶段。测量监理必须适时地进行检测,并严格按照规范要求,督促施工方做好放样及施工测量工作。
关键词 住宅楼 测量监理 轴线检测 标高检测
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大直径盾构管片水平拼装试验方法探究 被引量:3
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作者 吴朱茂 《铁道建筑技术》 2020年第4期35-39,共5页
大直径盾构管片水平拼装试验存在效率低下甚至失败的情况,不能真实全面反映产品尺寸精度。分析其原因除大直径管片体积大、重量大的因素外,主要原因在于现有的试验设备工装简陋、试验方法粗放、规范要求低等。结合当前水平拼装的规范要... 大直径盾构管片水平拼装试验存在效率低下甚至失败的情况,不能真实全面反映产品尺寸精度。分析其原因除大直径管片体积大、重量大的因素外,主要原因在于现有的试验设备工装简陋、试验方法粗放、规范要求低等。结合当前水平拼装的规范要求,分析现有试验方法存在的不足,对现有拼装设备工装进行改造,制定高标准的、更加严格的工艺措施,创造性地提出在每层管片拼装时增加标高检测的新思路。将新方法应用于南京长江第五大桥夹江隧道工程管片水平拼装试验,结果良好,证明了此试验方法的科学性与有效性。 展开更多
关键词 大直径盾构管片 水平拼装 支撑底座 楔形量 标高检测
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Label-free high-throughput and real-time detections of protein interactions by oblique-incidence reflectivity difference method 被引量:1
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作者 HE LiPing LIU Shuang +5 位作者 DAI JunBeijing National Laboratory for Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Lü HuiBin JIN KuiJuan YANG GuoZhen 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS 2014年第4期615-618,共4页
Selected Mouse IgG of 1 mg/mL as target was fabricated on microarray for 500 sample dots.Label-free and real-time reaction dynamic processes were detected between the microarrays with Goat Anti-mouse IgG of 0.02 mg/mL... Selected Mouse IgG of 1 mg/mL as target was fabricated on microarray for 500 sample dots.Label-free and real-time reaction dynamic processes were detected between the microarrays with Goat Anti-mouse IgG of 0.02 mg/mL using the obliqueincidence reflectivity difference(OIRD)method.We obtained the reaction results and the reaction dynamic curves of 500 protein dots.In addition,we also used label-free detection of protein microarrays of 10080 sample dots,including BSA and different concentrations of Mouse IgG and Rabbit IgG,by OIRD.The obtained reaction results between the protein microarray with 1 mg/mL Goat Anti-mouse IgG and 1 mg/mL Goat Anti-rabbit IgG are reported herein.Experimental results show that OIRD can be not only label-free high-throughput detection method for biological microarrays but also label-free real-time detection in the interaction processes of biomolecules. 展开更多
关键词 oblique-incidence reflectivity difference(OIRD) LABEL-FREE REAL-TIME HIGH-THROUGHPUT
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A novel RHT-TBD approach for weak targets in HPRF radar 被引量:6
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作者 Hongbo YU Guohong WANG +1 位作者 Wei WU Shuncheng TAN 《Science China Earth Sciences》 SCIE EI CAS CSCD 2016年第12期59-72,共14页
A novel approach, which can handle ambiguous data from weak targets, is proposed within the randomized Hough transform track-before-detect(RHT-TBD) framework. The main idea is that, without the pre-detection and ambig... A novel approach, which can handle ambiguous data from weak targets, is proposed within the randomized Hough transform track-before-detect(RHT-TBD) framework. The main idea is that, without the pre-detection and ambiguity resolution step at each time step, the ambiguous measurements are mapped by the multiple hypothesis ranging(MHR) procedure. In this way, all the information, based on the relativity in time and pulse repetition frequency(PRF) domains, can be gathered among different PRFs and integrated over time via a batch procedure. The final step is to perform the RHT with all the extended measurements, and the ambiguous data is unfolded while the detection decision is confirmed at the end of the processing chain.Unlike classic methods, the new approach resolves the problem of range ambiguity and detects the true track for targets. Finally, its application is illustrated to analyze and compare the performance between the proposed approach and the existing approach. Simulation results exhibit the effectiveness of this approach. 展开更多
关键词 high pulse repetition frequency weak targets TRACK-BEFORE-DETECT randomized Hough transform multiple hypothesis ranging range ambiguity resolution
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