目的:评价栝楼皮注射液对老年高血压患者生活质量和血压的影响。方法:将38例老年高血压患者按随机数字表法分成两组,对照组(18例)采用常规降压等治疗,治疗组(20例)在对照组的基础上加用栝楼皮注射液12 m l加入质量分数为5%的葡萄糖中静...目的:评价栝楼皮注射液对老年高血压患者生活质量和血压的影响。方法:将38例老年高血压患者按随机数字表法分成两组,对照组(18例)采用常规降压等治疗,治疗组(20例)在对照组的基础上加用栝楼皮注射液12 m l加入质量分数为5%的葡萄糖中静脉滴注,每日1次,治疗2周。观察两组治疗后患者临床证候改善情况及治疗前后24 h动态血压的变化。结果:治疗组患者临床证候中胸闷、便秘改善均明显优于对照组(P均<0.05);两组治疗后24 h动态血压均呈一致性显著下降,且治疗组夜间收缩压降低较明显(P<0.05);治疗组总有效率为85.0%,对照组为61.1%,差异有显著性(P<0.05)。结论:栝楼皮注射液与西药联合治疗老年高血压,有改善患者生活质量、辅助降低血压的效果,且未见不良反应。展开更多
[Objective] This study aimed to investigate the differences in chemical composition of supercritical CO2 extraction products in peels of Trichosanthes kirilowii Maxim. from Changqing district. [Method] Supercritical f...[Objective] This study aimed to investigate the differences in chemical composition of supercritical CO2 extraction products in peels of Trichosanthes kirilowii Maxim. from Changqing district. [Method] Supercritical fluidextraction (SFE) and GCMS method were applied to determine and analyze the chemical components of the extracts in peels of three strains of Trichosanthes kirilowii Maxim. [Result] The chemical components of supercritical CO2 extraction products in peels of three strains of Trichosanthes kirilowii Maxim. varied., and the number of chemical components with normalized percentage content higher than 1% was 5, 7 and 8, respectively. There are 14 kinds of common components, and the relative content of hexadecanoic acid was the highest. [Conclusion] Supercritical CO2 extracts in peels of different strains of Trichosanthes kirilowii Maxim. contain different chemical components, providing scientific basis for breeding excellent varieties and the development and utilization of Trichosanthes kirilowii Maxim.展开更多
文摘目的:评价栝楼皮注射液对老年高血压患者生活质量和血压的影响。方法:将38例老年高血压患者按随机数字表法分成两组,对照组(18例)采用常规降压等治疗,治疗组(20例)在对照组的基础上加用栝楼皮注射液12 m l加入质量分数为5%的葡萄糖中静脉滴注,每日1次,治疗2周。观察两组治疗后患者临床证候改善情况及治疗前后24 h动态血压的变化。结果:治疗组患者临床证候中胸闷、便秘改善均明显优于对照组(P均<0.05);两组治疗后24 h动态血压均呈一致性显著下降,且治疗组夜间收缩压降低较明显(P<0.05);治疗组总有效率为85.0%,对照组为61.1%,差异有显著性(P<0.05)。结论:栝楼皮注射液与西药联合治疗老年高血压,有改善患者生活质量、辅助降低血压的效果,且未见不良反应。
基金Supported by Science and Technology Development Project of Shangdong Province "Study on Standardized Planting of Chinese Herbal Medicines in Central China and Comprehensive Development and Utilization Technology of Bulk Chinese Herbs"(2011BAI06B00)Construction Project of Scientific and Technological Plat form for Quality Control of Genuine Medicinal Materials in Shangdong Province(2008GG-2NS02022)+1 种基金Agricultural Thoroughbred Breeding Project of Shangdong Province(2009LZ01-03)Independent Innovation Project of Universities and Institutes from Science and Technology Bureau of Ji'nan City(200906028)~~
文摘[Objective] This study aimed to investigate the differences in chemical composition of supercritical CO2 extraction products in peels of Trichosanthes kirilowii Maxim. from Changqing district. [Method] Supercritical fluidextraction (SFE) and GCMS method were applied to determine and analyze the chemical components of the extracts in peels of three strains of Trichosanthes kirilowii Maxim. [Result] The chemical components of supercritical CO2 extraction products in peels of three strains of Trichosanthes kirilowii Maxim. varied., and the number of chemical components with normalized percentage content higher than 1% was 5, 7 and 8, respectively. There are 14 kinds of common components, and the relative content of hexadecanoic acid was the highest. [Conclusion] Supercritical CO2 extracts in peels of different strains of Trichosanthes kirilowii Maxim. contain different chemical components, providing scientific basis for breeding excellent varieties and the development and utilization of Trichosanthes kirilowii Maxim.