Objective: There is only one neuropathologic report of congenital fibrosis of the extraocular muscles (CFEOM), and none of synergistic divergence. The aim of this report was to study the oculomotor nerve and the abduc...Objective: There is only one neuropathologic report of congenital fibrosis of the extraocular muscles (CFEOM), and none of synergistic divergence. The aim of this report was to study the oculomotor nerve and the abducens nerve in 2 such p atients with magnetic resonance imaging. Design: Observational case reports. Met hods: Ophthalmologic examination and thin-sectioned magnetic resonance imaging across the brainstem level were performed in 2 patients with CFEOM and synergist ic divergence. To confirm the accuracy of the procedure, we compared the results obtained with those of a control group of 40 individuals using the same techniq ue. Main Outcome Measures: The oculomotor nerve and the abducens nerve on magnet ic resonance imaging. Results: Magnetic resonance imaging disclosed bilateral hy poplasia of the oculomotor nerve in both patients, and absence of the abducens n erve on the affected side of synergistic divergence. The oculomotor and abducens nerves were observed in 80 of 80 eyes (100%) screened as controls. C onclusions: In both patients with CFEOM and synergistic divergence, the oculomot or nerve was hypoplastic bilaterally, and the abducens nerve was absent on the s ide exhibiting synergistic divergence.展开更多
文摘Objective: There is only one neuropathologic report of congenital fibrosis of the extraocular muscles (CFEOM), and none of synergistic divergence. The aim of this report was to study the oculomotor nerve and the abducens nerve in 2 such p atients with magnetic resonance imaging. Design: Observational case reports. Met hods: Ophthalmologic examination and thin-sectioned magnetic resonance imaging across the brainstem level were performed in 2 patients with CFEOM and synergist ic divergence. To confirm the accuracy of the procedure, we compared the results obtained with those of a control group of 40 individuals using the same techniq ue. Main Outcome Measures: The oculomotor nerve and the abducens nerve on magnet ic resonance imaging. Results: Magnetic resonance imaging disclosed bilateral hy poplasia of the oculomotor nerve in both patients, and absence of the abducens n erve on the affected side of synergistic divergence. The oculomotor and abducens nerves were observed in 80 of 80 eyes (100%) screened as controls. C onclusions: In both patients with CFEOM and synergistic divergence, the oculomot or nerve was hypoplastic bilaterally, and the abducens nerve was absent on the s ide exhibiting synergistic divergence.