Comparing with the predictions of the transitional dynamical symmetry E（5） proposed by Iachello [Phys. Rev. Lett. 85 （2000） 3580], the critical behaviors from U（5）-0（6） are studied in the space of two control ...Comparing with the predictions of the transitional dynamical symmetry E（5） proposed by Iachello [Phys. Rev. Lett. 85 （2000） 3580], the critical behaviors from U（5）-0（6） are studied in the space of two control parameters in the interacting boson model. A simple shape phase diagram has been presented. It is found that E（5） predictions cannot be exactly reproduced by our calculations and that the best agreement is close to the calculations with boson number N = 9. By comparing with experimental data on E（5）-like nuclei, we find that E（5） predictions and IBM calculations can reproduce the energy ratios and E2 transition ones.展开更多
The a＋^2＋ Ne elastic scattering angular distributions at lower incident energies of Eα= 12.7-31.1 Me V have been analyzed by using the a-folding potential based on the α＋^16O structure model of the ^20Ne nucleus....The a＋^2＋ Ne elastic scattering angular distributions at lower incident energies of Eα= 12.7-31.1 Me V have been analyzed by using the a-folding potential based on the α＋^16O structure model of the ^20Ne nucleus. The a-folding potential with a standard Woods-Saxon type imaginary part, can reasonably describe experimental cross sections and the anomalous large angle scattering （ALAS） features. The anomaly of the a＋^20Ne scattering system is further confirmed , in the lower incident energy region.展开更多
We discuss the nucleon spin structure function g<SUB>1</SUB> and the difference between the proton and neutron targets , based on quark model calculation. Quark-hadron duality for the nucleon spin structur...We discuss the nucleon spin structure function g<SUB>1</SUB> and the difference between the proton and neutron targets , based on quark model calculation. Quark-hadron duality for the nucleon spin structure function is also analyzed. Effects of the Δ(1232) and Roper P<SUB>11</SUB>(1440) resonances on the spin structure function and on the difference are mentioned. The results of different models for the Roper resonance are also addressed.展开更多
This paper is a short revisit to Kuo-Brown effective interaction derived from the Hamada-Johnston nucleon-nucleon potential, done by Gerry Brown and Tom Kuo. This effective interaction, derived in year 1966, is the fi...This paper is a short revisit to Kuo-Brown effective interaction derived from the Hamada-Johnston nucleon-nucleon potential, done by Gerry Brown and Tom Kuo. This effective interaction, derived in year 1966, is the first attempt to describe nuclear structure properties from the free nucleon-nucleon potential. Nowadays much progress has been achieved for the effective interactions in shell model. We would compare the effective interactions obtained in the 1966 paper with up-to-date shell-model interactions in sd-shell and pf-shell model space. Recent knowledge of effective interactions on nuclear structure, can also be traced in the KuoBrown effective interaction, i.e., the universal roles of central and tensor forces, which reminds us that such discovery should be noticed much earlier.展开更多
The N≈Z nuclei in the mass A^80 region has been researched because of an abundance of nuclear structure phenomena.The projected shell model(PSM)was adopted to investigate the structure of high spin state in proton-ri...The N≈Z nuclei in the mass A^80 region has been researched because of an abundance of nuclear structure phenomena.The projected shell model(PSM)was adopted to investigate the structure of high spin state in proton-rich 74,76,78Kr isotopes including yrast spectra,moment of inertia,electric quadrupole transitions and the behavior of single particle.The calculated results are in good agreement with available data and the shape coexistence in low-spin is also discussed.展开更多
OBJECTIVE: To investigate the effect of Lingguizhugan decoction (LGZGD) on changes of cardiac structure and function, and its putative mechanism of action, by investigating mRNA and protein expression of myocardial nu...OBJECTIVE: To investigate the effect of Lingguizhugan decoction (LGZGD) on changes of cardiac structure and function, and its putative mechanism of action, by investigating mRNA and protein expression of myocardial nuclear factor kappa B(NF-κB), and the plasma content of NF-κB in rats with chronic heart failure.METHODS: The chronic heart failure (CHF) model in rats was induced by coronary artery ligation.Sham operation was performed in control rats. Six weeks after the procedure, rats were randomly classified into the various treatment groups: model CHF, Captopril (4.4 mg/kg), low LGZGD dose (2.1 g/kg), medium LGZGD dose (4.2 g/kg), and high LG-ZGD dose (8.4 g/kg). Treatments continued for 4 consecutive weeks. Changes of hemodynamic indices were observed by the PowerLab data acquisition and analysis system. Morphological changes of myocardium were observed by hematoxylin and eosin staining, and Masson staining. The mRNA and protein expression of myocardial NF-κB were detected by reverse transcription-polymerase chain reaction and western blotting, respectively. The plasma content of NF-κB was detected by enzyme-linked immuno-sorbent assay.RESULTS: CHF rats showed significant dysfunction in hemodynamic indices and in cardiac structure.Compared with the sham operation group, mRNA expression of myocardial NF-κB and plasma content of NF-κB of the model group was significantly increased. All three doses of LGZGD, and Captopril,improved the hemodynamic dysfunction, and inhibited the change of cardiac structure while significantly improving the survival rate. Furthermore,compared with the model group, mRNA expression of myocardial NF-κB and plasma content of NF-κB were significantly reduced by all dosage groups of LGZGD as well as the\Captopril group.CONCLUSION: In CHF rats, LGZGD improves changes of cardiac structure and function via its inhibition of NF-κB.展开更多
An integrated approach is proposed to predict the chromatographic retention time of oligonucleotides based on quantitative structure-retention relationships （QSRR） models. First, the primary base sequences of oligon...An integrated approach is proposed to predict the chromatographic retention time of oligonucleotides based on quantitative structure-retention relationships （QSRR） models. First, the primary base sequences of oligonucleotides are translated into vectors based on scores of generalized base properties （SGBP）, involving physicochemical, quantum chemical, topological, spatial structural properties, etc.; thereafter, the sequence data are transformed into a uniform matrix by auto cross covariance （ACC）. ACC accounts for the interactions between bases at a certain distance apart in an oligonucleotide sequence; hence, this method adequately takes the neighboring effect into account. Then, a genetic algorithm is used to select the variables related to chromatographic retention behavior of oligonuclcotides. Finally, a support vector machine is used to develop QSRR models to predict chromatographic retention behavior. The whole dataset is divided into pairs of training sets and test sets with different proportions; as a result, it has been found that the QSRR models using more than 26 training samples have an appropriate external power, and can accurately represent the relationship between the features of sequences and structures, and the retention times. The results indicate that the SGBP-ACC approach is a useful structural representation method in QSRR of oligonucleotides due to its many advantages such as plentiful structural information, easy manipulation and high characterization competence. Moreover, the method can further be applied to predict chromatographic retention behavior of oligonucleotides.展开更多
基金The project supported in part by National Natural Science Foundation of China under Grant Nos. 10265001 and 10547003, the Natural Science Foundation of Inner Mongolian under Grant No. 200607010111, and the Key Scientific Research Fund of Educational Bureau of Inner Mongolian under Grant No. NJ05007 .Acknowledgments The authors are greatly indebted to Prof. G.L. Long for his continuing interest in this work and his many suggestions.
文摘Comparing with the predictions of the transitional dynamical symmetry E（5） proposed by Iachello [Phys. Rev. Lett. 85 （2000） 3580], the critical behaviors from U（5）-0（6） are studied in the space of two control parameters in the interacting boson model. A simple shape phase diagram has been presented. It is found that E（5） predictions cannot be exactly reproduced by our calculations and that the best agreement is close to the calculations with boson number N = 9. By comparing with experimental data on E（5）-like nuclei, we find that E（5） predictions and IBM calculations can reproduce the energy ratios and E2 transition ones.
基金Supported by National Natural Science Foundation of China under Grant No.10865002
文摘The a＋^2＋ Ne elastic scattering angular distributions at lower incident energies of Eα= 12.7-31.1 Me V have been analyzed by using the a-folding potential based on the α＋^16O structure model of the ^20Ne nucleus. The a-folding potential with a standard Woods-Saxon type imaginary part, can reasonably describe experimental cross sections and the anomalous large angle scattering （ALAS） features. The anomaly of the a＋^20Ne scattering system is further confirmed , in the lower incident energy region.
文摘We discuss the nucleon spin structure function g<SUB>1</SUB> and the difference between the proton and neutron targets , based on quark model calculation. Quark-hadron duality for the nucleon spin structure function is also analyzed. Effects of the Δ(1232) and Roper P<SUB>11</SUB>(1440) resonances on the spin structure function and on the difference are mentioned. The results of different models for the Roper resonance are also addressed.
基金supported by the National Natural Science Foundation of China(Grant Nos.11275067 and 11447109)the support from the Helmholtz Association(HGF)through the Nuclear Astrophysics Virtual Institute(VH-VI-417)
文摘This paper is a short revisit to Kuo-Brown effective interaction derived from the Hamada-Johnston nucleon-nucleon potential, done by Gerry Brown and Tom Kuo. This effective interaction, derived in year 1966, is the first attempt to describe nuclear structure properties from the free nucleon-nucleon potential. Nowadays much progress has been achieved for the effective interactions in shell model. We would compare the effective interactions obtained in the 1966 paper with up-to-date shell-model interactions in sd-shell and pf-shell model space. Recent knowledge of effective interactions on nuclear structure, can also be traced in the KuoBrown effective interaction, i.e., the universal roles of central and tensor forces, which reminds us that such discovery should be noticed much earlier.
基金supported by the National Natural Science Foundation of China(Grant Nos.11305059,11275067,11275068 and 11135005)
文摘The N≈Z nuclei in the mass A^80 region has been researched because of an abundance of nuclear structure phenomena.The projected shell model(PSM)was adopted to investigate the structure of high spin state in proton-rich 74,76,78Kr isotopes including yrast spectra,moment of inertia,electric quadrupole transitions and the behavior of single particle.The calculated results are in good agreement with available data and the shape coexistence in low-spin is also discussed.
基金Supported by the National Natural Science Fund of China(No.30973707)National Natural Science Fund of China Youth Project(No.81202631)+1 种基金Natural Science Fund of Anhui Province(No.070413262X)Anhui Provincial Science and Technology Projects (No.10021303024)
文摘OBJECTIVE: To investigate the effect of Lingguizhugan decoction (LGZGD) on changes of cardiac structure and function, and its putative mechanism of action, by investigating mRNA and protein expression of myocardial nuclear factor kappa B(NF-κB), and the plasma content of NF-κB in rats with chronic heart failure.METHODS: The chronic heart failure (CHF) model in rats was induced by coronary artery ligation.Sham operation was performed in control rats. Six weeks after the procedure, rats were randomly classified into the various treatment groups: model CHF, Captopril (4.4 mg/kg), low LGZGD dose (2.1 g/kg), medium LGZGD dose (4.2 g/kg), and high LG-ZGD dose (8.4 g/kg). Treatments continued for 4 consecutive weeks. Changes of hemodynamic indices were observed by the PowerLab data acquisition and analysis system. Morphological changes of myocardium were observed by hematoxylin and eosin staining, and Masson staining. The mRNA and protein expression of myocardial NF-κB were detected by reverse transcription-polymerase chain reaction and western blotting, respectively. The plasma content of NF-κB was detected by enzyme-linked immuno-sorbent assay.RESULTS: CHF rats showed significant dysfunction in hemodynamic indices and in cardiac structure.Compared with the sham operation group, mRNA expression of myocardial NF-κB and plasma content of NF-κB of the model group was significantly increased. All three doses of LGZGD, and Captopril,improved the hemodynamic dysfunction, and inhibited the change of cardiac structure while significantly improving the survival rate. Furthermore,compared with the model group, mRNA expression of myocardial NF-κB and plasma content of NF-κB were significantly reduced by all dosage groups of LGZGD as well as the\Captopril group.CONCLUSION: In CHF rats, LGZGD improves changes of cardiac structure and function via its inhibition of NF-κB.
基金supported by the National Natural Science Foundation of China (10901169)National 111 Programme of Introducing Talents of Discipline to Universities (0507111106)+2 种基金Innovation Ability Training Foundation of Chongqing University (CDCX008)Innovative Group Program for Graduates of Chongqing University,ScienceInnovation Fund (200711C1A0010260)
文摘An integrated approach is proposed to predict the chromatographic retention time of oligonucleotides based on quantitative structure-retention relationships （QSRR） models. First, the primary base sequences of oligonucleotides are translated into vectors based on scores of generalized base properties （SGBP）, involving physicochemical, quantum chemical, topological, spatial structural properties, etc.; thereafter, the sequence data are transformed into a uniform matrix by auto cross covariance （ACC）. ACC accounts for the interactions between bases at a certain distance apart in an oligonucleotide sequence; hence, this method adequately takes the neighboring effect into account. Then, a genetic algorithm is used to select the variables related to chromatographic retention behavior of oligonuclcotides. Finally, a support vector machine is used to develop QSRR models to predict chromatographic retention behavior. The whole dataset is divided into pairs of training sets and test sets with different proportions; as a result, it has been found that the QSRR models using more than 26 training samples have an appropriate external power, and can accurately represent the relationship between the features of sequences and structures, and the retention times. The results indicate that the SGBP-ACC approach is a useful structural representation method in QSRR of oligonucleotides due to its many advantages such as plentiful structural information, easy manipulation and high characterization competence. Moreover, the method can further be applied to predict chromatographic retention behavior of oligonucleotides.
