Helpfulness of the combination of acetic acid and FICE in the detection of Barrett's epithelium and Barrett's associated neoplasias

AIM:To investigate the mucosal morphology in Barrett's oesophagus by chromo and magnifying endoscopy.METHODS:A prospective pilot study at a tertiary medical centre was conducted to evaluate the use of acetic acid pulverisation combined with virtual chromoendoscopy using Fujinon intelligent chromoendoscopy(FICE) for semiological characterization of the mucosal morphology in Barrett's oesophagus and its neoplastic complications.Upper endoscopy using high definition whitelight,2% acid acetic pulverisation and FICE with high definition videoendoscopy were performed in 20 patients including 18 patients who presented with aspects of Barrett's oesophagus at endoscopy examination.Two patients used as controls had normal endoscopy and histological results.Prospectively,videos were watched blind from histological results by three trained FICE technique endoscopists.RESULTS:The videos of patients with high-grade dysplasia showed an irregular mucosal pattern in 14% using high definition white light endoscopy and in 100% using acid acetic-FICE combined.Videos did not identify irregular vascular patterns using high definition white light endoscopy,while acid acetic-FICE combined visualised one in 86% of cases.CONCLUSION:Combined acetic acid and FICE is a promising method for screening high-grade dysplasia and early cancer in Barrett's oesophagus.

胃镜检查前口服二甲硅油乳剂的效果观察

观察在胃镜检查前予以患者二甲硅油乳剂口服的效果。方法 观察对象选择于2021.7~2022.7在我院接受胃镜检查的患者78例,随机方式施以分组观察,在检查前施以二甲硅油乳剂口服的39例患者分入研究组,在检查前施以盐酸达克罗宁胶浆的39例患者分入对照组,对比和观察干预效果。结果 与对照组比较,检查清晰度方面(A级61.54%、B级30.77%、C级5.13%、D级2.56%)研究组更佳(P<0.05);与对照组(11.55±2.36)min比较,检查时间方面研究组(7.08±2.25)min更短(P<0.05);与对照组(20.51%))较,不良反应研究组(2.56%)较少(P<0.05);与对照组对比,研究组微小病灶检出率明显较高(P<0.05)。结论 在胃镜检查前施以患者二甲硅油乳剂可获得满意的效果,在检查清晰度、检查时间和不良反应方面优势更为明显,建议推广。