棕褐沙林蚁水提物抗炎作用初探

为观察棕褐沙林蚁水提物对佐剂性关节炎的保护作用 ,用二甲苯制作小鼠耳郭肿胀模型 ,称量耳片 ,计算肿胀度 ;用弗氏完全佐剂制作大鼠佐剂性关节炎模型 ,用容积法测量大鼠足跖肿胀率 ;用分光光度计法测量前列腺素E2 (PGE2 )。结果 :小鼠灌胃给予棕褐沙林蚁水提物 2、4g/kg时 ,对二甲苯所致小鼠耳郭肿胀有显著抑制作用 ,其作用类似于消炎痛。棕褐沙林蚁水提物 1 0 0、45 0、90 0mg/kg连续用药 ,均可明显剂量依赖性地抑制大鼠佐剂性关节炎的原发性及继发性炎症反应 ,可降低炎症局部的PGE2 质量浓度 ,其作用与吡罗昔康相似。

生态卫生系统的发展与实践现状

生态卫生系统的基本思想是对生活污水进行分类收集及源处理,以期实现可分别进行营养盐循环回用及水资源再生利用的可持续型废物管理模式。对生态卫生系统的核心理念和发展及实践现状进行了讨论,并对该系统在我国的实施提出了建议。

Seasonal Variations of Net-Phytoplankton Community Structure in the Southern Yellow Sea

Based on the field survey data of four cruises in 2011,all phytoplankton communities in the southern Yellow Sea (SYS) were investigated for the species composition,dominant species,abundance and diversity indices.A total of 379 species belonging to9 phyla were identified,of which the most abundant group was Bacillariophyta (60.9%) ,followed by Pyrrophyta (23.7%) and Haptophyta (6.9%) .The seasonal distribution of abundance was:summer (4137.1×103ind m 3) >spring (3940.4×103ind m 3) >winter (3010.6×103ind m 3) >autumn (340.8×103ind m 3) ,while the horizontal distribution showed a decreasing tendency from inshore to offshore regions.The dominant species of phytoplankton varied in different seasons.The dominant species were Thalassiosira pacifica,Skeletoema spp.and Chaetoceros cinctus in spring,Chaetoceros debbilis,Chaetoceros pseudocurvisetus and Chaetoceros curvisetus in summer,Thalassiosira curviseriata,Alexandrium catenella and Ceratium fusus in autumn,Paralia sulcata,Phaeocystis sp.and Bacillaria paradoxa in winter,respectively.In SYS,the group of temperate coastal species was the major ecotype,and the groups of the central SYS species and oceanic species were also important constituents.The average values of Shannon-Weaver diversity index (H’) and Pielou evenness index (J) were 2.37 and 0.65 respectively.The indices H’and J in the open sea were higher than those in coastal waters.Obvious co-variation tendencies between H’and J were observed in all but the summer cruise of this survey.

RNA/DNA Ratio and LPL and MyoD mRNA Expressions in Muscle of Oreochromis niloticus Fed with Elevated Levels of Palm Oil

Palm oil is of great potential as one of the sustainable alternatives to fish oil(FO) in aquafeeds.In this present study,five isonitrogenous diets(32% crude protein) with elevated palm oil levels of 0%,2%,4%,6% and 8% were used during an 8-week feeding trial to evaluate its effects on RNA/DNA ratio and lipoprotein lipase(LPL) and Myo D m RNA expressions in muscle of Oreochromis niloticus.The results showed that RNA,DNA content as well as ratio of RNA to DNA were significantly affected(P < 0.05),in each case the highest was recorded in fish group subjected to 6% palm oil level.There was a strong positive correlation between nucleic acid concentration(RNA concentration and RNA:DNA ratio) and specific growth rate(SGR),protein efficiency ratio(PER),while a negative correlation existed between nucleic acid concentration(RNA concentration and RNA:DNA ratio) and feed conversion ratio(FCR).The m RNA expressions of LPL and Myo D in muscle were not significantly affected by the different palm oil levels,although the highest expression was observed in fish fed with 6% palm oil level.There also existed a strong positive correlation between the m RNA expression of LPL,Myo D and SGR,PER,while their correlation with FCR was negative.In conclusion,elevated palm oil affected the RNA,DNA concentration as well as RNA/DNA ratio significantly,although the m RNA expression of LPL and Myo D were not affected significantly by elevated palm oil levels.

Effects of fractal surface on rheological behavior and combustion kinetics of modified brown coal water slurries

The paper reports the effects of surface fractal structures on the rheological behavior and combustion kinetics of raw brown coal and three modified coal water slurries （CWSs）. The results show that the fractal structures and physicochemical properties of samples are dependent on various modification processes. The apparent viscosities of the coal water slurries increase with increasing surface fractal dimensions （D）, especially with decreasing shear rates. Fur- thermore, it has been proved that the ignition temperatures and apparent activation energies of modified CWSs are lower than that of raw coal water slurry. Compared with the traditional qualitative analysis of the effect of pore structures on CWSs properties, D can more efficiently indicate the quantificational effect of pore structures on the rheological behavior and combustion kinetics of CWSs.

源分离技术的国内外研发进展及应用现状

污水末端处理的最大缺陷是以大量清洁水稀释人粪、尿等排泄物,并经管道收集、输送后进行集中处理。现代生活中卫生而不生态的水冲便器不仅浪费和污染大量水资源,而且也彻底阻断了营养物质回归土地的生态之路。因此,污水末端处理方式日益受到质疑。粪便与尿液从源头分离可从根本上改变末端处理的弊端,原生态的生活习惯可通过粪、尿液分离便器达到既生态又卫生的目的。从尿液源分离概念及优越性入手,首先概述了包括生态卫生(ECOSAN)在内的源分离技术最新研究进展。其次,总结并讨论了源分离技术在国内外的工程应用实例。最后,对源分离技术的未来发展进行了展望。

Zic1 negatively regulates brown adipogenesis in C_3H_(10)T_(1/2) cells

Zinc finger in the cerebellum 1 （Zicl） is known to regulate neurogenesis and myogenesis in the develop- mental stage and widely used as one of the brown adipocyte-specific markers. In this study, we examined the effect of Zicl on brown adipogenesis. Overexpression of Zicl attenuated the lipid accumulation and the expressions of PPAR72 and C/EBPα in C3H10T1/2 mesenchymal stem cells. The mRNA levels of BAT-specific thermogenic genes （PRDM16, PGC-1α and UCP1） and fatty acid oxidation regulatory genes （PPARα, CPT1α, CPT1β and COX7α1） were suppressed in Zicl-overexpressed cells. Moreover, overexpression of Zicl reduced the mitochondrial oxidative phosphorylation （OXPHOS） regulatory proteins including ATP5α, UQCRC2, SDHB and NDUFB5. These results indicate a potential role of Zicl in the regulation of brown adipogenesis via inhibiting adipogenesis, fatty acid oxidation and mitochondrial OXPHOS.