二次元营销品牌植入化、互动化的发展趋势

随着二次元文化越来越为国人所接受,二次元营销也日益展现出其强大的效力。其营销策略时刻以消费者需求为中心,并借助品牌植入化、互动化为消费者提供全方位的服务,不断用创新和创意加大其无形资产的开发和利用,为品牌营销树立了标杆,指引了方向。

“三教”改革背景下高职课程植入式模块化教学的创新与实践——以《植物与植物生理》课程为例

探讨了在三教改革背景下,高职《植物与植物生理》课程如何进行植入式模块化教学的创新与实践。通过对课程现状的分析,重新设计课程内容、整合教学资源、创新教学方法等措施,旨在提升学生学习兴趣和自主学习能力,并通过实践验证了其有效性和可行性,旨在为进一步探索该教学模式在其他课程中的应用和推广提供有益的参考和借鉴。

计算机辅助设计定制化植入体在复杂眶周畸形治疗中的应用

目的探讨计算机辅助设计定制化植入体,对复杂眶周畸形患者治疗的准确性和安全性。方法本文回顾了2009年1月至2012年12月,于我科接受计算机辅助设计定制化植入体治疗的眶周复杂畸形患者共106例,将患者术后6月CT扫描重建影像与术前计算机模拟设计行表面几何学差异分析,判断植入体与术前设计间的差异,并统计患者并发症的发生情况。结果 106例患者中,采集6个月后随访CT共105例,植入体形态平均误差(1.32±1.64)mm,85.72%的患者误差小于2 mm。除1例患者由于反复的额窦感染,在术后2个月取出植入体,其余患者均未发生严重的并发症。结论计算机辅助定制化植入体,治疗眶周复杂畸形高效、准确、安全,可作为复杂眶周畸形临床治疗的推荐方案之一。

模块化植入式教学在军训长效机制构建中的运用

军训作为学生国防教育的重要内容,是学校开展国防教育的重要形式。然而研究发现,我国高校的军训更多注重的是对学生的身心教育,而关于高校军训长效机制构建则研究甚少,这无疑将军训局限在高校课程之外,对国家人才培养以及学生的综合发展都是巨大的损失。而该文正是以模块化植入式教学在军训长效机制构建中的运用为中心点,即对军训长效机制构建进行研究性报告,也把军训通过模块化植入式,更科学的发展为一门重要的必修课,提出并完善课外军训体系构建,推动了国防教育的发展。

影视植入式广告娱乐化的影响分析

植入式广告作为一种新兴的广告形式一出现便受到了无数品牌方的青睐。在这个网络快速迭代,"00后"逐渐加入互联网大军,以张扬个性、不受拘束的特点赋予了互联网新的呈现形式,钟情于潜移默化的植入式广告以达到软性教化大众的效果是每个营销人员的首选。如何在用户对各种广告司空见惯的情况下让品牌方更好地搭载娱乐元素与受众更有效地沟通值得每个营销达人绞尽脑汁去思考。

Investigation of a new design for zirconia dental implants

Objective:To assess the biomechanical properties of a new design configuration for zirconia dental implants. Methods: The new design has a cylindrical shape that is partially hollow and porous in the bottom, which permits the implants to be locked into the alveolar bone over time. It also utilizes bioactive glass coatings to increase adhesion to surrounding bone structure. Samples of the new design were fabricated in the laboratory and their material strength, hardness, and fracture toughness were evaluated. In addition, biocompatibility of the new design was evaluated through testing in dogs. Results: Results of mechanical tests indicate that structural properties of the new design exceed the usual requirements for implants. Moreover, animal tests suggest that there is appreciable improvement in lock-in strength and osteointegration. Conclusion: The new design configuration is biomechanically feasible and further research is warranted to improve the design for human use.

Luminescence Properties of Nanometer Si with Embedded Structure

Blue luminescence at about 431nm is obtained from epitaxial silicon after C+ implantation,annealing in hydrogen ambience and chemical etching sequentially.With increase of chemical etching,the blue peak is enhanced at first,then decreased and substituted by a red peak at last.C=O compounds are introduced during C+ implantation and embedded in the surface of nanometer Si formed during annealing,and at last is formed nanometer silicon with embedded structure,which contributes to the blue emission.Presented is the possible mechanism of photoluminescence.

Effect of solution treatment on corrosion characteristics of biodegradable Mg-6Zn alloy

A binary Mg-6Zn biodegradable alloy was solution treated to evaluate the effects of resulting microstructure changes on the alloy＇s degradation rate and mechanisms in-vitro. The treatment was conducted at 350 °C for 6-48 h. Optical and scanning electron microscopy, energy-dispersive X-ray spectroscopy and X-ray diffraction were used to analyze the as-cast and treated samples. Immersion and electrochemical tests were performed in simulated body fluid at 37 °C to assess the samples corrosion resistance. To confirm the results of the corrosion tests, p H measurement was carried out. It is found that over 24 h solution treatment dissolves intermetallic phases in matrix and produces an almost single phase microstructure. Decreasing the intermetallic phases results in lower cathode/anode region ratios and lowers corrosion rates. The results of the electrochemical and mass loss tests reveal that extended solution treatment improves the corrosion resistance of the alloy. The results also show that solution at 350 °C for 24 h enhances the corrosion resistance of the as-cast alloy more than 60%. In addition, decreasing intermetallic phases in the microstructure accompanied a lower p H rise reduced corrosion rate. Solution treatment is suggested as a corrosion improving process for the application of Mg-Zn alloys as biodegradable implant materials.

Cutting-balloon angioplasty before drug-eluting stent implantation for the treatment of severely calcified coronary lesions

Background Severely calcified coronary lesions respond poorly to balloon angioplasty, resulting in incomplete and asymmetrical stent expansion. Therefore, adequate plaque modification prior to drug-eluting stent （DES） implantation is the key for calcified lesion treat- ment. This study was to evaluate the safety and efficacy of cutting balloon angioplasty for severely calcified coronary lesions. Methods Ninety-two consecutive patients with severely calcified lesions （defined as calcium arc 〉 180% calcium length ratio 〉 0.5） treated with bal- loon dilatation before DES implantation were randomly divided into two groups based on the balloon type： 45 patients in the conventional balloon angioplasty （BA） group and 47 patients in the cutting balloon angioplasty （CB） group. Seven cases in BA group did not satisfactorily achieve dilatation and were transferred into the CB group. Intravascular ultrasound （IVUS） was performed before balloon dilatation and after stent implantation to obtain qualitative and quantitative lesion characteristics and evaluate the stent, including minimum lumen cross-sectional area （CSA）, calcified arc and length, minimum stent CSA, stent apposition, stent symmetry, stent expansion, vessel dissection, and branch vessel jail. In-hospital, 1-month, and 6-month major adverse cardiac events （MACE） were reported. Results There were no statistical differences in clinical characteristics between the two groups, including calcium arc （222.2° ± 22.2° vs. 235.0° ± 22.1 °, p=0.570）, calcium length ratio （0.67 ± 0.06 vs. 0.77± 0.05, P = 0.130）, and minimum lumen CSA before PCI （2.59 ±0.08 mm2 vs. 2.52 ± 0.08 mm2, P = 0.550）. After stent implantation, the final minimum stent CSA （6.26 ± 0.40 mm2 vs. 5.03 ± 0.33 mm2; P = 0.031） and acute lumen gain （3.74 ±0.38 mm2 w. 2.44 ± 0.29 mm2, P = 0.015） were significantly larger ila the CB group than that of the BA group. There were not statis tically differences in stent expansion, stent symmetry, incomplete stent apposition, vessel dissection and branch vessel jail between two groups. The 30-day and 6-month MACE rates were also not different. Conclusions Cutting balloon angioplasty before DES implantation in severely calcified lesions appears to be more efficacies including significantly larger final stent CSA and larger acute lumen gain, without increasing complications during operations and the MACE rate in 6-month.

Therapeutic effect of rotational atherectomy with implantation of drug eluting stent in heavily coronary calcified patients

Background Rotational atherectomy （RA） could facilitate the percutaneous coronary intervention （PCI） in heavily coronary calcified patients. The effectiveness and safety of this technique needs to be further evaluated. Methods ＆ Results Eighty patients who underwent RA in our center from September 2011 to June 2014 were enrolled. The mean age was 72.4 ± 10.4 years. The left ventricular ejection frac- tion （LVEF） was average 52.3% ± 8.48% and the estimated glomerular filtration rate was 73.2 ± 3.20 mL/min per 1.73 m2. The coronary lesions were complex, with Syntax score 29.5 ± 9.86. The diameter of reference vessel was 3.4 ± 0.45 mm and the average diameter stenosis of target vessels was 80% ~ 10%. All the patients were deployed with drug eluting stents （DES） successfully aiter RA. The patients were followed up for 12-18 months. Kaplan-Meier plots estimated the survival rate was 93.4% and the cumulative incidence of major adverse cardiac and cerebral events （MACCE） was 25.4%. Bleeding and procedural-related complications were quite low. COX proportional hazards model for multivariate analysis demonstrated that diabetes, LVEF and maximum pressure of postdilatation were the predictors of MACCE. Conclusions RA followed by implantation of DES was effective and safe for heavily coronary calcified patients. Diabetes, LVEF and maximum pressure ofpostdilatation were predictive for MACCE.

Characterization of gastric cancer models from different cell lines orthotopically constructed using improved implantation techniques

AIM:To develop orthotopic gastric cancer mouse models from different cell lines and characterize the tumor features to assist further in preclinical trials and clinical treatment strategies.METHODS:Human gastric cancer SGC-7901 and BGC823 cell suspensions were injected subcutaneously into nude mice to develop solid tumors,and tumor tissue pieces were then implanted under the serous coat of the stomach.An autopsy was performed on all animals of the SGC-7901 and BGC-823 models to observe the primary tumor growth and metastases using pathological and immunohistochemical methods.RESULTS:Both models showed large tumors in situ resulting in pressure and infiltration of the adjacent organs.The gastric cavity became smaller,along with stenosis of the cardia or pylorus.There were biological and statistical differences between the two models.The metastasis rate in involved organs (lymph nodes,kidney,spleen,testis) was significantly higher in the BGC-823 model compared to the SGC-7901 model (P < 0.05 or P < 0.01).The median survival of the BGC-823 model was shorter than that of SGC-7901 (23 d vs 84 d,P < 0.05).Histopathologically,the primary tumor and metastatic lesions of the two models showed obvious atypia and mucus in the cytoplasm.Compared with the SGC-7901 model,BGC-823 appeared more poorly differentiated (absence of adenoid structure),had a smaller volume,and richer capillary structure.Immunohistochemical staining revealed cytokeratin 20 and epithelial membrane antigen expression was positive in the SGC-7901 tumors,while negative in BGC-823 ones.CONCLUSION:Models using the SGC-7901 and BGC-823 cell lines were established which could function in gastric cancer research on carcinogenesis mechanism and drug discovery.The two models showed different tumor behavior and the latter was more malignant than the former.

从《饭局的诱惑》分析综艺节目创新式场景营销

目前《饭局的诱惑》已上线6期,点击量近2亿,不管是在斗鱼还是腾讯视频都获得了广泛的关注。无论是在内容制作上还是商业营销上,米未传媒都在不断突破旧的模式,探索更多玩法,带给观众和客户更多有趣的内容。可以说这种产品植入应用化营销的尝试,是更加精进的场景营销新模式,即将带来一场中国网综植入甚至中国电视界的大变革。

Study on the Allelopathic Effects of Alien Invasive Species Cenchrus echinatus on Seed Germination and Seedling Growth of Solanaceae Crops

[Objective] This study aimed to investigate the potential ecological dam- ages of alien invasive species Cenchrus echinatus. [Method] By using seed germi- nation method, the effects of different concentrations of C. echinatus aqueous extracts on seed germination and seedling growth of three Solanaceae crops were investigated. [Result] After incubated for 5 d, no significant differences were observed in germination speed indices of Lycopersicum esculentum seeds between aqueous extract groups and control groups; germination speed indices of Solarium melongena seeds were significantly reduced with the increasing concentration of Cenchrus echinatus aqueous extracts; however, Capsicum frutescens seeds in various groups were not germinated. After incubated for 7 d, root lengths of Lycopersicum esculentum seedlings were inhibited with the increasing concentration of Cenchrus echinatus aqueous extracts, while stem lengths and comprehensive allelopathic effects were promoted; germination rates of Solanum melongena seeds in various groups were all significantly lower than control groups; root length, stem length and comprehen- sive allelopathic effects in higher concentration groups were inhibited; germination rates of Capsicum frutescens seeds were significantly inhibited, and those in the highest concentration group were not generated. After incubated for 14 d, all indica- tors of Solanum melongena were significantly inhibited; various indicators of Capsicum frutescens in the highest concentration group were significantly inhibited. [Conclusion] The sensitivity of three Solanaceae crops to Cenchrus echinatus aqueous extracts presented an overall order of Solanum melongena 〉 Capsicum frutescens 〉 Lycopersicum esculentum, suggesting that Cenchrus echinatus can to some extent inhibit the growth of several crops, which should be strictly prevented and controlled in agricultural production.

Effects of Nitrogen Deposition on Tundra Vegetation Undergoing Invasion by Deyeuxia angustifolia in Changbai Mountains

In recent years, herbaceous species such as Deyeuxia angustifolia （Kom.） Y. L. Chang has invaded alpine tundra regions of the western slope of the Changbai Mountains. Because atmospheric nitrogen deposition is predicted to increase under a warming climate and D. angustifolia is sensitive to nitrogen addition, field experiments were conducted from 2010 to 2013 to determine the effect of increased nitrogen deposition on the mechanisms of D. angustifolia invasion. The goal of this study is to evaluate the impact of increased nitrogen deposition on the changes in alpine tundra vegetation （consisting mostly of Rhododendron chrysanthum Pall. and Vaccinium uliginosum Linn.）. The results showed that： 1） simulated nitrogen deposition affected overall characteristics and structure of R. chrysanthum and E uliginosum communities and had a positive impact on the growth of tundra vegetation invaded by 1）. angustifolia; 2） R. chrysanthum was more resistant to invasion by D. angustifolia than V.. uliginosum; 3） simulated nitrogen deposition could improve the growth and enhance the competitiveness of D. angustifolia, which was gradually replacing R. chrysanthum and V. uliginosum and might become the dominant species in the system in future, transforming alpine tundra into alpine meadow in the Chanebai Mountains.

Significance and Measures of Chinese Culture Implanting Into College English Teaching

It is commonly believed that Imaguage serves as the carrier of culture and one part of it. And language teaching is inseparable from cultural knowledge impartment. So, teachers should attach great importance to cultural background when teaching English language. Unfortunately, aphasia of Chinese culture occurs when they value Western culture and ignore the infiltration of Chinese culture. Under such circumstances, this paper demonstrates the importance of implanting Chinese culture into college English teaching and proposes corresponding measures for Chinese cultural implantation

Naturalization of Landscaping Woody Plant, Magnolia obovata Potentially Invasive Species

Magnolia obovata, a tree species native to Japan, is a traditional landscaping tree that has also been introduced to various countries. M. obovata individuals have recently emerged in non-planting areas in Korea, prompting us to investigate its distribution by establishing Dosolsan in an urban forest of Daejeon City as the target site. In order to determine its naturalization, the study explored the status of population growth by examining the diameter at breast height of the individuals, and diameter diminution quotient was calculated. Cores of the trees were collected, and the age distribution was estimated by regression analysis. Reproduction possibility was analyzed by verifying the flowerblooming and fruit-bearing. Spontaneous colonization was investigated in the other potential sites which have different location and environment, respectively.The diameter distribution showed a reverse J-shaped curve, and the diminution quotient was ≥ 1.8. The population was composed of different generations,thus confirming the growth of the population. The distributed M. obovata grew and flowered normally,and followed a normal life cycle. The same phenomenon was observed in other planting areas,residual forests in urban or rural areas, alluvial islands, and mountain forests. The continuous spread of M. obovata in new ecosystems may be attributable to its long-term distribution by birds, relatively fast growth, and maturity time. Investigations on the naturalization and spread of M. obovata in Korea, as well as in various countries, are warranted.

A hardware/software co-optimization approach for embedded software of MP3 decoder

In order to improve the efficiency of embedded software running on processor core, this paper proposes a hard-ware/software co-optimization approach for embedded software from the system point of view. The proposed stepwise methods aim at exploiting the structure and the resources of the processor as much as possible for software algorithm optimization. To achieve low memory usage and low frequency need for the same performance, this co-optimization approach was used to optimize embedded software of MP3 decoder based on a 16-bit fixed-point DSP core. After the optimization, the results of decoding 128 kbps, 44.1 kHz stereo MP3 on DSP evaluation platform need 45.9 MIPS and 20.4 kbytes memory space. The optimization rate achieves 65.6% for memory and 49.6% for frequency respectively compared with the results by compiler using floating-point computation. The experimental result indicates the availability of the hardware/software co-optimization approach depending on the algorithm and architecture.

Synthesis and characterization of Ti-Co alloy foam for biomedical applications

Highly porous Ti-Co alloy specimens for biomedical applications were synthesized by powder metallurgy based space holder technique. Ti alloys have high melting temperature and affinity for oxygen, which makes Ti alloys difficult to be processed. The Co addition reduces the melting temperature and Ti-Co alloy was sintered at lower temperatures. The electrochemical corrosion behaviour of the specimens was examined in the artificial saliva solution. The effects of Co content of the alloy, the p H value and fluoride concentration of the artificial saliva solution on the electrochemical corrosion properties of the specimens were investigated. The microstructure and mechanical properties of the specimens were examined. The electrochemical impedance spectroscopy results indicate that the corrosion resistance of the specimens decreases at high fluoride concentrations and low p H value. The defect density increases with increasing the fluoride concentration and decreasing the p H value of artificial saliva according to Mott-Schottky analysis.

Cardiac resynchronization in the elderly is beneficial, but could we implant our devices in old patients safer？

We read with interest the article by Olechowski, et aL recently published in the Journal of Geriatric Cardiology. The results of this retrospective analysis of patients under- going cardiac resynchronization therapy （CRT） device implantation are in line with previous reports, suggesting that resynchronization therapy in the elderly is feasible and may lead to significant improvement of cardiac function and clinical status.

Expression of Bmi-1 and EZH2 in tissues adjacent to human epithelial ovarian cancer cells of orthotopic implantation in nude mice

Objective This study investigated the feasibility of screening residual normal ovarian tissues based on the expression of Bmi-1 and EZH2 in tissues adjacent to orthotopic ovarian carcinomas in nude mice. Methods The human epithelial ovarian cancer cell line OVCAR3 was grown in subcutaneous tissues and the tumor tissues were orthotopically implanted. The expression levels of Bmi-1 and EZH2 were detected by immunohistochemical staining and RT-PCR in cancer tissues, proximal and remote tissues with respect to the cancer tissues, and normal ovarian tissues of nude mice.Results Thirty-five ovarian tissue samples with normal biopsy results were obtained from 40 cases of human epithelial ovarian cancer in the nude mice in which the tumor tissues were orthotopically implanted. Bmi-1 and EZH2 expression levels were lower in proximal paraneoplastic tissue samples than in cancer tissue samples(P < 0.05) and higher than in remote paraneoplastic tissue samples(P < 0.01). No significant difference was found in the expression levels of Bmi-1 and EZH2 using immunohistochemistry among residual normal ovarian tissues obtained from orthotopically implanted models that differed in severity. The expression of Bmi-1 and EZH2 was negative in 20 normal ovarian tissue samples.Conclusion The expression levels of Bmi-1 and EZH2 were reduced with increasing distance from the cancer tissues. Negative expression of these tumor-associated genes can be used as a standard for the screening of normal ovarian tissues adjacent to tumor tissues. Normal ovarian tissues can be obtained from the tissues adjacent to tumors.