Objective To investigate the antioxidant,antimicrobial and wound healing potential of Helicteres isora Linn.leaf extracts.Methods The petroleum ether,chloroform,acetone,ethanol and hydroalcoholic extracts of leaves we...Objective To investigate the antioxidant,antimicrobial and wound healing potential of Helicteres isora Linn.leaf extracts.Methods The petroleum ether,chloroform,acetone,ethanol and hydroalcoholic extracts of leaves were screened for phytochemicals.The 1,1-diphenyl-2-picrylhydrazyl(DPPH),nitric oxide(NO)radical scavenging tests and reducing power assays were performed to measure antioxidant activity;disc diffusion methods were used to evaluate antimicrobial potential.Wound healing activity was evaluated by incision and excision wound rat models.Results The extracts contained mainly sterols and flavonoids.The hydroalcoholic extract showed remarkable antioxidant and antimicrobial potential and significant(P<0.05)wound healing activity.Conclusions The identified activities of the hydroalcoholic extract may be attributable to its constituent phytochemicals.展开更多
Citrus sinensis commonly called sweet orange belongs to the family Rutaceae. Nutritionally, it is highly recommended due to its high content of micronutrients. However, the rejection of a large amount of epicarp in na...Citrus sinensis commonly called sweet orange belongs to the family Rutaceae. Nutritionally, it is highly recommended due to its high content of micronutrients. However, the rejection of a large amount of epicarp in nature contributes to the emission of greenhouse gas and the development of leachate which contaminate surface water and groundwater. The aim of this work was to identify the essential oil components from Citrus sinensis epicarp, and then look after the biological activity of these components in order to underline the worth to reuse the Citrus sinensis epicarp as a gainful mean. The essential oil of 4,000 g of Citrus sinensis epicarp was done through the water steam distillation and 0.0287 g of essential oil was obtained; so a yield of 0.0007%. The essential oil was then submitted to gas chromatography-flame ionization detector (GC-F1D). The result revealed that the essential oil was teemed with 28 volatile compounds, including terpene compounds (50%), aldehydes (32%) and alcohols (18%) whose anti-inflammatory, anti-diabetic, larvicidal and antioxidant activities were underlined.展开更多
文摘Objective To investigate the antioxidant,antimicrobial and wound healing potential of Helicteres isora Linn.leaf extracts.Methods The petroleum ether,chloroform,acetone,ethanol and hydroalcoholic extracts of leaves were screened for phytochemicals.The 1,1-diphenyl-2-picrylhydrazyl(DPPH),nitric oxide(NO)radical scavenging tests and reducing power assays were performed to measure antioxidant activity;disc diffusion methods were used to evaluate antimicrobial potential.Wound healing activity was evaluated by incision and excision wound rat models.Results The extracts contained mainly sterols and flavonoids.The hydroalcoholic extract showed remarkable antioxidant and antimicrobial potential and significant(P<0.05)wound healing activity.Conclusions The identified activities of the hydroalcoholic extract may be attributable to its constituent phytochemicals.
文摘Citrus sinensis commonly called sweet orange belongs to the family Rutaceae. Nutritionally, it is highly recommended due to its high content of micronutrients. However, the rejection of a large amount of epicarp in nature contributes to the emission of greenhouse gas and the development of leachate which contaminate surface water and groundwater. The aim of this work was to identify the essential oil components from Citrus sinensis epicarp, and then look after the biological activity of these components in order to underline the worth to reuse the Citrus sinensis epicarp as a gainful mean. The essential oil of 4,000 g of Citrus sinensis epicarp was done through the water steam distillation and 0.0287 g of essential oil was obtained; so a yield of 0.0007%. The essential oil was then submitted to gas chromatography-flame ionization detector (GC-F1D). The result revealed that the essential oil was teemed with 28 volatile compounds, including terpene compounds (50%), aldehydes (32%) and alcohols (18%) whose anti-inflammatory, anti-diabetic, larvicidal and antioxidant activities were underlined.