经骶裂孔置管盘外注射胶原酶治疗腰椎间盘突出症187例

目的 :对 2 0 0 0年 3月至 2 0 0 1年 12月间 ,2 5 4例应用脊椎微创介入术 (MinimallyInvasiveTechnic ,MIT)治疗腰椎间盘突出症患者进行研究。方法 :回访术后 1.5～ 3年患者 ,统计其视觉模拟评分 (VisualAnalogueScale ,VAS) ,以及介入后持续治疗情况 ,并对照MIT治疗前、治疗后 3～ 5天的VAS。结果 :失访 6 7例 ,对获得 187例资料VAS对照 ,治疗前为 8.5 7± 0 .5 5 ;治疗后 3～ 7天为 3.2 9± 0 .76 ;1.5年～ 3年为 2 .38± 0 .74 ,与治疗前和治疗后 3～ 7天对照差异显著 (P <0 .0 5 )。治疗后 1.5～ 3年 15 4(82 .4 % )例疼痛完全解除 ;2 8(15 .0 % )例需要间断治疗 ;5 (2 .7% )例接受手术治疗。结论 :MIT可以使 82 .4 %椎间盘突出患者治疗 1.5～ 3年后疼痛没再复发。

胶原酶治疗腰椎间盘突出症的临床观察

本文报告了硬膜外腔前间隙置管,并用微管输液泵注射胶原酶治疗腰椎问盘突出症60例,优良率达81．67％。并探讨了此法的作用机理及适应症的选择与疗效的关系。作者对胶原酶盘外注射法治疗腰突症进行临床观察。现将治疗60例疗效结果总结如下。

Peridural Injection of Mailuoning Compound Liquor for Treatment of Prolapse of Lumbar Intervertebral Disc in 100 Cases

Objective: To observe the therapeutic effects of peridural injection of Mailuoning Compound Liquor (脉络宁复合液) for prolapse of lumbar intervertebral disc (PLID). Methods: Peridural injection of Mailuoning Compound Liquor (MCL) was given to 100 cases of PLID, once a week, 4 sessions constituting a therapeutic course. By adopting the scoring method, observations were carried out on the total therapeutic effect and changes in the 13 items of the symptoms and signs. Results: After treatment, the JOA scores in this series of patients were markedly enhanced as compared with the scores before treatment, showing significant differences in the paired t test (P<0.05). The sum of the excellent and good rates was 64%, and the total effective rate was 97%. All the scores in the 13 items under observation were significantly raised as compared with the scores before treatment (P<0.05). Conclusion: Peridural injection of MCL is an effective and safe therapy for PLID, and with shorter treating course, quicker therapeutic effects, and less suffering for the patients.