Automatic reading procedures in colon cells biopsies allow a faster and precise reading of microscopic biopsies. These procedures implement automatic image segmentation in order to classify cell types as cancerous or ...Automatic reading procedures in colon cells biopsies allow a faster and precise reading of microscopic biopsies. These procedures implement automatic image segmentation in order to classify cell types as cancerous or noncancerous. The authors have developed a new approach aiming to detect colon cancer cells derived from the ＂Snake＂ method but using a progressive division of the dimensions of the image to achieve rapid segmentation. The aim of the present paper was to classify different cancerous cell types based on nine morphological parameters and on probabilistic neural network. Three types of cells were used to assess the efficiency of our classifications models, including BH （Benign Hyperplasia）, IN （Intraepithelial Neoplasia） that is a precursor state for cancer, and Ca （Carcinoma） that corresponds to abnormal tissue proliferation （cancer）. Results showed that among the nine parameters used to classify cells, only three morphologic parameters （area, Xor convex and solidity） were found to be effective in distinguishing the three types of cells. In addition, classification of unknown cells was possible using this method.展开更多
文摘Automatic reading procedures in colon cells biopsies allow a faster and precise reading of microscopic biopsies. These procedures implement automatic image segmentation in order to classify cell types as cancerous or noncancerous. The authors have developed a new approach aiming to detect colon cancer cells derived from the ＂Snake＂ method but using a progressive division of the dimensions of the image to achieve rapid segmentation. The aim of the present paper was to classify different cancerous cell types based on nine morphological parameters and on probabilistic neural network. Three types of cells were used to assess the efficiency of our classifications models, including BH （Benign Hyperplasia）, IN （Intraepithelial Neoplasia） that is a precursor state for cancer, and Ca （Carcinoma） that corresponds to abnormal tissue proliferation （cancer）. Results showed that among the nine parameters used to classify cells, only three morphologic parameters （area, Xor convex and solidity） were found to be effective in distinguishing the three types of cells. In addition, classification of unknown cells was possible using this method.
