It aims to investigate the protective effects of sodium hyaluronate,panthenol,Portulaca oleracea L.and Calendula officinalis L.on hyperosmotic dehydration-induced injury of human immortalized keratinocytes(HaCaT).The ...It aims to investigate the protective effects of sodium hyaluronate,panthenol,Portulaca oleracea L.and Calendula officinalis L.on hyperosmotic dehydration-induced injury of human immortalized keratinocytes(HaCaT).The safety mass concentrations of four raw materials were screened by detecting cell viability,and the secretion of hyaluronic acid(HA)was determined using the ELISA method.The expression of HaCaT barrier function related genes(OVOL1,EREG,TGM1,TGM2,IVL,IRF6,THBS1,CASP14)was detected at the mRNA level to explore the regulatory effect of four raw materials on these genes.The results demonstrate that pretreatment with the four kinds of raw materials could increase the cell viability after hyperosmotic dehydration,promote the secretion of HA,and improve the expression of barrier function related genes after hyperosmotic dehydration,among which panthenol and Calendula officinalis L.are better.The results show that the four raw materials have a certain protective effect on the hyperosmotic dehydration cell model,which provides data support for its application in cosmetics.展开更多
Based on the finite element （FE） program ANSYS, a three-dimensional model for the Runyang Suspension Bridge （RSB） is established. The structural natural frequency, vibration mode, stress and displacement response ...Based on the finite element （FE） program ANSYS, a three-dimensional model for the Runyang Suspension Bridge （RSB） is established. The structural natural frequency, vibration mode, stress and displacement response under various load cases are given. A new method of FE model updating is presented based on the physical meaning of sensitivity and the penalty function concept. In this method, the structural model is updated by modifying the parameters of design, and validated by structural natural vibration characteristics, stress response as well as displacement response. The design parameters used for updating are bounded according to measured static response and engineering judgment. The FE model of RSB is updated and validated by the measurements coming from the structural health monitoring system （SHMS）, and the FE baseline model reflecting the current state of RSB is achieved. Both the dynamic and static results show that the method is effective in updating the FE model of long span suspension bridges. The results obtained provide an important research basis for damage alarming and health monitoring of the RSB.展开更多
Current dynamic finite element model updating methods are not efficient or restricted to the problem of local optima. To circumvent these, a novel updating method which integrates the meta-model and the genetic algori...Current dynamic finite element model updating methods are not efficient or restricted to the problem of local optima. To circumvent these, a novel updating method which integrates the meta-model and the genetic algorithm is proposed. Experimental design technique is used to determine the best sampling points for the estimation of polynomial coefficients given the order and the number of independent variables. Finite element analyses are performed to generate the sampling data. Regression analysis is then used to estimate the response surface model to approximate the functional relationship between response features and design parameters on the entire design space. In the fitness evaluation of the genetic algorithm, the response surface model is used to substitute the finite element model to output features with given design parameters for the computation of fitness for the individual. Finally, the global optima that corresponds to the updated design parameter is acquired after several generations of evolution. In the application example, finite element analysis and modal testing are performed on a real chassis model. The finite element model is updated using the proposed method. After updating, root-mean-square error of modal frequencies is smaller than 2%. Furthermore, prediction ability of the updated model is validated using the testing results of the modified structure. The root-mean-square error of the prediction errors is smaller than 2%.展开更多
In order to establish the relationship between the measured dynamic response and the health status of long-span bridges, a double-layer model updating method for steel-concrete composite beam cable-stayed bridges is p...In order to establish the relationship between the measured dynamic response and the health status of long-span bridges, a double-layer model updating method for steel-concrete composite beam cable-stayed bridges is proposed. Measured frequencies are selected as the first-layer reference data, and the mass of the bridge deck, the grid density, the modulus of concrete and the ballast on the side span are modified by using a manual tuning technique. Measured global positioning system （GPS） data is selected as the second-layer reference data, and the degradation of the integral structure stiffness EI of the whole bridge is taken into account for the second-layer model updating by using the finite element iteration algorithm. The Nanpu Bridge in Shanghai is taken as a case to verify the applicability of the proposed model updating method. After the first-layer model updating, the standard deviation of modal frequencies is smaller than 7%. After the second-layer model updating, the error of the deflection of the mid-span is smaller than 10%. The integral structure stiffness of the whole bridge decreases about 20%. The research results show a good agreement between the calculated response and the measured response.展开更多
A model updating optimization algorithm under quadratic constraints is applied to structure dynamic model updating. The updating problems of structure models are turned into the optimization with a quadratic constrain...A model updating optimization algorithm under quadratic constraints is applied to structure dynamic model updating. The updating problems of structure models are turned into the optimization with a quadratic constraint. Numerical method is presented by using singular value decomposition and an example is given. Compared with the other method, the method is efficient and feasible.展开更多
In order to investigate the existence of a stable long-run equilibrium relationship between economic growth and consumption in China, the relationship between the gross domestic product （GDP） and consumption in Chin...In order to investigate the existence of a stable long-run equilibrium relationship between economic growth and consumption in China, the relationship between the gross domestic product （GDP） and consumption in China was investigated by the cointegration analysis method. Using the Engle-Granger （EG） test and considering the possibility of structural changes, the impact of external economic shocks on the long-run equilibrium relationship between economic growth and consumption in China was analyzed. Analysis results show that without considering structural changes, the EG test cannot detect cointegration in the series subjected to structural changes; in considering structural changes, cointegration is successfully detected by specifying the dummy variable. In addition, the error correction models were constructed in different periods. This study verifies the existence of a long-run equilibrium relationship between economic growth and consumption in China, and this relationship has significantly changed in 1989 and 1997, respectively.展开更多
A self-normalized statistic the modified modal scintillation index MMSI is proposed and defined as the variance of the modulus of modal excitation normalized by the square of its expected value over some observation i...A self-normalized statistic the modified modal scintillation index MMSI is proposed and defined as the variance of the modulus of modal excitation normalized by the square of its expected value over some observation intervals.It is proved in an analytical form that the MMSI is a depth dependent signature and independent of the source level and the source range under the condition of the ideal waveguide while the classical modal scintillation index MSI depends on both the source level and the source range.The MSI and the MMSI in the Pekeris waveguide at 70 Hz are simulated with different source levels and source ranges by the Kraken normal mode model.The simulation results are consistent with the theoretical deduction.The MMSI probability density functions PDFs of different normal modes for surface and submerged sources are calculated using the mode filtering methods with the same variations of vertical motions.It is indicated that the PDFs can be used to separate the submerged and the surface sources except for the fourth mode.展开更多
How to achieve the objective of reducing CO2 emissions has been an academic focus in China recently. The factors influencing CO2 emissions are the vital issue to accomplish the arduous target. Firstly, three influenti...How to achieve the objective of reducing CO2 emissions has been an academic focus in China recently. The factors influencing CO2 emissions are the vital issue to accomplish the arduous target. Firstly, three influential factors, the energy consumption, the proportion of tertiary industry in gross domestic product （GDP）, and the degree of dependence on foreign trade, are carefully selected, since all of them have closer grey relation with China＇s COz emissions compared with others when the grey relational analysis （GRA） method is applied. The study highlights co-integration relation of these four variables using the co-integration analysis method. And then a long-term co-integration equation and a short-term error correction model of China＇s CO2 emissions are devel- oped. Finally, the comparison is exerted between the forecast value and the actual value of China＇s CO2 emissions based on error correction model. The results and the relevant statistics tests show that the pro- posed model has better explanation capability and credibility.展开更多
To provide some feasible condition-based maintenance （CBM） decision making methods for civil aeroengine, firstly, the theory of aeroengine CBM decision making is described. The proportional intensity（PI） model is ...To provide some feasible condition-based maintenance （CBM） decision making methods for civil aeroengine, firstly, the theory of aeroengine CBM decision making is described. The proportional intensity（PI） model is established based on the reliability and condition monitoring data. According to the model, the decision making methods are proposed for the optimal preventive maintenance（PM） interval and removal. Then, the time on wing （TOW） is predicted by collecting actual data based on the engine age and operating conditions. Finally, an example of a fleet for CF6-80C2 engines is illustrated. It shows that sufficient engine operation data are the key of accurate decision making. Results indicate that the CBM decision making methods are helpful for engineers in airlines to control engine maintenance actions and TOW, thus decreasing risks and maintenance costs.展开更多
文摘It aims to investigate the protective effects of sodium hyaluronate,panthenol,Portulaca oleracea L.and Calendula officinalis L.on hyperosmotic dehydration-induced injury of human immortalized keratinocytes(HaCaT).The safety mass concentrations of four raw materials were screened by detecting cell viability,and the secretion of hyaluronic acid(HA)was determined using the ELISA method.The expression of HaCaT barrier function related genes(OVOL1,EREG,TGM1,TGM2,IVL,IRF6,THBS1,CASP14)was detected at the mRNA level to explore the regulatory effect of four raw materials on these genes.The results demonstrate that pretreatment with the four kinds of raw materials could increase the cell viability after hyperosmotic dehydration,promote the secretion of HA,and improve the expression of barrier function related genes after hyperosmotic dehydration,among which panthenol and Calendula officinalis L.are better.The results show that the four raw materials have a certain protective effect on the hyperosmotic dehydration cell model,which provides data support for its application in cosmetics.
文摘Based on the finite element （FE） program ANSYS, a three-dimensional model for the Runyang Suspension Bridge （RSB） is established. The structural natural frequency, vibration mode, stress and displacement response under various load cases are given. A new method of FE model updating is presented based on the physical meaning of sensitivity and the penalty function concept. In this method, the structural model is updated by modifying the parameters of design, and validated by structural natural vibration characteristics, stress response as well as displacement response. The design parameters used for updating are bounded according to measured static response and engineering judgment. The FE model of RSB is updated and validated by the measurements coming from the structural health monitoring system （SHMS）, and the FE baseline model reflecting the current state of RSB is achieved. Both the dynamic and static results show that the method is effective in updating the FE model of long span suspension bridges. The results obtained provide an important research basis for damage alarming and health monitoring of the RSB.
文摘Current dynamic finite element model updating methods are not efficient or restricted to the problem of local optima. To circumvent these, a novel updating method which integrates the meta-model and the genetic algorithm is proposed. Experimental design technique is used to determine the best sampling points for the estimation of polynomial coefficients given the order and the number of independent variables. Finite element analyses are performed to generate the sampling data. Regression analysis is then used to estimate the response surface model to approximate the functional relationship between response features and design parameters on the entire design space. In the fitness evaluation of the genetic algorithm, the response surface model is used to substitute the finite element model to output features with given design parameters for the computation of fitness for the individual. Finally, the global optima that corresponds to the updated design parameter is acquired after several generations of evolution. In the application example, finite element analysis and modal testing are performed on a real chassis model. The finite element model is updated using the proposed method. After updating, root-mean-square error of modal frequencies is smaller than 2%. Furthermore, prediction ability of the updated model is validated using the testing results of the modified structure. The root-mean-square error of the prediction errors is smaller than 2%.
基金The Special Project of the Ministry of Construction ofChina (No.20060909).
文摘In order to establish the relationship between the measured dynamic response and the health status of long-span bridges, a double-layer model updating method for steel-concrete composite beam cable-stayed bridges is proposed. Measured frequencies are selected as the first-layer reference data, and the mass of the bridge deck, the grid density, the modulus of concrete and the ballast on the side span are modified by using a manual tuning technique. Measured global positioning system （GPS） data is selected as the second-layer reference data, and the degradation of the integral structure stiffness EI of the whole bridge is taken into account for the second-layer model updating by using the finite element iteration algorithm. The Nanpu Bridge in Shanghai is taken as a case to verify the applicability of the proposed model updating method. After the first-layer model updating, the standard deviation of modal frequencies is smaller than 7%. After the second-layer model updating, the error of the deflection of the mid-span is smaller than 10%. The integral structure stiffness of the whole bridge decreases about 20%. The research results show a good agreement between the calculated response and the measured response.
文摘A model updating optimization algorithm under quadratic constraints is applied to structure dynamic model updating. The updating problems of structure models are turned into the optimization with a quadratic constraint. Numerical method is presented by using singular value decomposition and an example is given. Compared with the other method, the method is efficient and feasible.
文摘In order to investigate the existence of a stable long-run equilibrium relationship between economic growth and consumption in China, the relationship between the gross domestic product （GDP） and consumption in China was investigated by the cointegration analysis method. Using the Engle-Granger （EG） test and considering the possibility of structural changes, the impact of external economic shocks on the long-run equilibrium relationship between economic growth and consumption in China was analyzed. Analysis results show that without considering structural changes, the EG test cannot detect cointegration in the series subjected to structural changes; in considering structural changes, cointegration is successfully detected by specifying the dummy variable. In addition, the error correction models were constructed in different periods. This study verifies the existence of a long-run equilibrium relationship between economic growth and consumption in China, and this relationship has significantly changed in 1989 and 1997, respectively.
基金The National Natural Science Foundation of China(No.11104029)
文摘A self-normalized statistic the modified modal scintillation index MMSI is proposed and defined as the variance of the modulus of modal excitation normalized by the square of its expected value over some observation intervals.It is proved in an analytical form that the MMSI is a depth dependent signature and independent of the source level and the source range under the condition of the ideal waveguide while the classical modal scintillation index MSI depends on both the source level and the source range.The MSI and the MMSI in the Pekeris waveguide at 70 Hz are simulated with different source levels and source ranges by the Kraken normal mode model.The simulation results are consistent with the theoretical deduction.The MMSI probability density functions PDFs of different normal modes for surface and submerged sources are calculated using the mode filtering methods with the same variations of vertical motions.It is indicated that the PDFs can be used to separate the submerged and the surface sources except for the fourth mode.
基金Supported by the National Natural Science Foundation of China(41101569)the China Postdoctoral Science Foundation Funded Project(2011M500965)+5 种基金the Jiangsu Funds of Social Science(11EYC023)the Doctoral Discipline New Teachers Fund(20110095120002)the Jiangsu Postdoctoral Science Foundation Funded Project(1102088C)the Fundamental Research Funds for the Central Universities(JGJ110763)the Talent Introduction Funds of China University of Mining and Technologythe Sail Plan Funds for Young Teachers of China University of Mining and Technology~~
文摘How to achieve the objective of reducing CO2 emissions has been an academic focus in China recently. The factors influencing CO2 emissions are the vital issue to accomplish the arduous target. Firstly, three influential factors, the energy consumption, the proportion of tertiary industry in gross domestic product （GDP）, and the degree of dependence on foreign trade, are carefully selected, since all of them have closer grey relation with China＇s COz emissions compared with others when the grey relational analysis （GRA） method is applied. The study highlights co-integration relation of these four variables using the co-integration analysis method. And then a long-term co-integration equation and a short-term error correction model of China＇s CO2 emissions are devel- oped. Finally, the comparison is exerted between the forecast value and the actual value of China＇s CO2 emissions based on error correction model. The results and the relevant statistics tests show that the pro- posed model has better explanation capability and credibility.
基金the National Natural Science Foundation of China(60672164)the National High Technology Research and Development Program of China(863Program)(2006AA04Z427)~~
文摘To provide some feasible condition-based maintenance （CBM） decision making methods for civil aeroengine, firstly, the theory of aeroengine CBM decision making is described. The proportional intensity（PI） model is established based on the reliability and condition monitoring data. According to the model, the decision making methods are proposed for the optimal preventive maintenance（PM） interval and removal. Then, the time on wing （TOW） is predicted by collecting actual data based on the engine age and operating conditions. Finally, an example of a fleet for CF6-80C2 engines is illustrated. It shows that sufficient engine operation data are the key of accurate decision making. Results indicate that the CBM decision making methods are helpful for engineers in airlines to control engine maintenance actions and TOW, thus decreasing risks and maintenance costs.
