A physically based analytical model was developed to predict the performance of the plateau observed in the gate C-V characteristics of strained-Si/SiGe pMOSFET.Experimental results were used to validate this model.Th...A physically based analytical model was developed to predict the performance of the plateau observed in the gate C-V characteristics of strained-Si/SiGe pMOSFET.Experimental results were used to validate this model.The extracted parameters from our model were tOX=20 nm,ND=1×1016cm 3,tSSi=13.2 nm,consistent with the experimental values.The results show that the simulation results agree with experimental data well.It is found that the plateau can be strongly affected by doping concentration,strained-Si layer thickness and mass fraction of Ge in the SiGe layer.The model has been implemented in the software for strained silicon MOSFET parameter extraction,and has great value in the design of the strained-Si/SiGe devices.展开更多
The explosion flow field in five straight pipes with different diameters and one bending pipe selected from a domestic coal mine are studied by the method of numerical simulation. And the results show that,both in the...The explosion flow field in five straight pipes with different diameters and one bending pipe selected from a domestic coal mine are studied by the method of numerical simulation. And the results show that,both in the straight and bending pipes, the pressure wave and velocity wave are accelerated by the rising of reaction rate. As the explosion progressed, with the temperature reaching approximately 3000 K, only one pressure wave and one reaction rate wave were observed, while several velocity waves were found.The larger diameter presented the highest relative pressure as well as the largest velocity increase and subsequent decrease inside the tube. The bent pipes caused both turbulence and kinetic energy to increase, resulting in the acceleration of the reaction rate. The burning time was 7.4% shorter than the burning time observed for the straight pipe. Based on these results, designing one explosion resistance device, and in the practical engineering applications, it was to be proved to meet the security requirements fully.展开更多
Based on the study about the geological background of Beiya Gold Deposit, numerical simulation was conducted about the three-dimensional structural stress field for Beiya Gold Deposit by applying finite element theory...Based on the study about the geological background of Beiya Gold Deposit, numerical simulation was conducted about the three-dimensional structural stress field for Beiya Gold Deposit by applying finite element theory and by employing a linear elasticity model. Results of the simulation indicate that the Beiya syncline is a faulted basin, and a hidden fracture occurs in the west wing of the syncline.Under the action of the EW-trending compressive force, four nearly NS-trending fractures (groups) were generated in the stress stretching areas of the two wings of the syncline, and these fractures constitute favorable tectonic positions for the upward intrusion of porphyry magma and the occurrence of Au-Pb-Zn polymetallic deposits.展开更多
Focusing on B2B market, this paper studies the effect of product differentiation on business model perlbrmance. After interviewing several experts and analyzing numbers of distributing questionnaires. the author disco...Focusing on B2B market, this paper studies the effect of product differentiation on business model perlbrmance. After interviewing several experts and analyzing numbers of distributing questionnaires. the author discovered that product differentiation has a positive effect on business model performance. Through SEM. it is revealed that product differentiation at each level have positive effect on business model, with different effect weight. The main contributions of this research are summarized as follows: Firstly, the proposed model of the product differentiation on business model performance lays the basis for scientific measurement of product differentiation and its effect on business model performance; Secondly, this research ranks the importance of product differentiation at different level in B2B market; Finally, this research provides a good reference for enterprises to update their product strategy for better business model performance.展开更多
Carbon nanotubes(CNTs)were grown into anodic aluminum oxide(AAO)channels by chemical vapor deposition(CVD)using C2H2/N2mixtures as feeding gas,which can be used as field emitters.The bottom surface of AAO template was...Carbon nanotubes(CNTs)were grown into anodic aluminum oxide(AAO)channels by chemical vapor deposition(CVD)using C2H2/N2mixtures as feeding gas,which can be used as field emitters.The bottom surface of AAO template was etched slightly and the tips of CNTs were explored as the field emission arrays which were uniform and vertical.Field emission characterization showed a low turn-on field about 3.25 V/m and high emission current about 30 mA/cm2with the electric field about 4 V/m.These superior field emission characteristics could be attributed to low density of vertical CNTs and higher conductivity of the substrate.展开更多
Engineered sequence-specific zinc finger nucleases (ZFNs) make the highly efficient modification of eukaryotic genomes possible.However,most current strategies for developing zinc finger nucleases with customized sequ...Engineered sequence-specific zinc finger nucleases (ZFNs) make the highly efficient modification of eukaryotic genomes possible.However,most current strategies for developing zinc finger nucleases with customized sequence specificities require the construction of numerous tandem arrays of zinc finger proteins (ZFPs),and subsequent largescale in vitro validation of their DNA binding affinities and specificities via bacterial selection.The labor and expertise required in this complex process limits the broad adoption of ZFN technology.An effective computational assisted design strategy will lower the complexity of the production of a pair of functional ZFNs.Here we used the FoldX force field to build 3D models of 420 ZFP-DNA complexes based on zinc finger arrays developed by the Zinc Finger Consortium using OPEN (oligomerized pool engineering).Using nonlinear and linear regression analysis,we found that the calculated protein-DNA binding energy in a modeled ZFP-DNA complex strongly correlates to the failure rate of the zinc finger array to show significant ZFN activity in human cells.In our models,less than 5% of the three-finger arrays with calculated protein-DNA binding energies lower than 13.132 kcal mol 1 fail to form active ZFNs in human cells.By contrast,for arrays with calculated protein-DNA binding energies higher than 5 kcal mol 1,as many as 40% lacked ZFN activity in human cells.Therefore,we suggest that the FoldX force field can be useful in reducing the failure rate and increasing efficiency in the design of ZFNs.展开更多
A comparative study with kerosene and hydrogen fuel in a model scramjet combustor has been carried out nu- merically. The effect of fuel-air equivalence ratio on the flow field properties in a cavity based mixing mech...A comparative study with kerosene and hydrogen fuel in a model scramjet combustor has been carried out nu- merically. The effect of fuel-air equivalence ratio on the flow field properties in a cavity based mixing mechanism at a freestream Math number of 2.08 has been probed. The investigation has been carried out in a two dimension- al numerical model where a cavity of length to depth ratio of 2 is mounted on one of the walls of the flow channel The flow field shock structure is observed to change with the change in fuel-air equivalence ratio. Total pressure loss is observed to depend both on fuel air equivalence ratio and the fuel type. The spread of fuel in the test sec- tion shows marked variation with the equivalence ratio. Performance of injector location on the fuel-air mixing is also probed during the course of the investigation.展开更多
基金Projects(51308040203,6139801)supported by National Ministries and Commissions,ChinaProjects(72105499,72104089)supported by the Fundamental Research Funds for the Central Universities,ChinaProject(2010JQ8008)supported by the Natural Science Basic Research Plan in Shaanxi Province of China
文摘A physically based analytical model was developed to predict the performance of the plateau observed in the gate C-V characteristics of strained-Si/SiGe pMOSFET.Experimental results were used to validate this model.The extracted parameters from our model were tOX=20 nm,ND=1×1016cm 3,tSSi=13.2 nm,consistent with the experimental values.The results show that the simulation results agree with experimental data well.It is found that the plateau can be strongly affected by doping concentration,strained-Si layer thickness and mass fraction of Ge in the SiGe layer.The model has been implemented in the software for strained silicon MOSFET parameter extraction,and has great value in the design of the strained-Si/SiGe devices.
基金supported by National Natural Science Foundation of China (No. 51174113)National Key Basic Research and Development Program (No. 2011CB201206)National Key Scientific Apparatus Development of Special Item (No. 2012YQ24012705)
文摘The explosion flow field in five straight pipes with different diameters and one bending pipe selected from a domestic coal mine are studied by the method of numerical simulation. And the results show that,both in the straight and bending pipes, the pressure wave and velocity wave are accelerated by the rising of reaction rate. As the explosion progressed, with the temperature reaching approximately 3000 K, only one pressure wave and one reaction rate wave were observed, while several velocity waves were found.The larger diameter presented the highest relative pressure as well as the largest velocity increase and subsequent decrease inside the tube. The bent pipes caused both turbulence and kinetic energy to increase, resulting in the acceleration of the reaction rate. The burning time was 7.4% shorter than the burning time observed for the straight pipe. Based on these results, designing one explosion resistance device, and in the practical engineering applications, it was to be proved to meet the security requirements fully.
文摘Based on the study about the geological background of Beiya Gold Deposit, numerical simulation was conducted about the three-dimensional structural stress field for Beiya Gold Deposit by applying finite element theory and by employing a linear elasticity model. Results of the simulation indicate that the Beiya syncline is a faulted basin, and a hidden fracture occurs in the west wing of the syncline.Under the action of the EW-trending compressive force, four nearly NS-trending fractures (groups) were generated in the stress stretching areas of the two wings of the syncline, and these fractures constitute favorable tectonic positions for the upward intrusion of porphyry magma and the occurrence of Au-Pb-Zn polymetallic deposits.
文摘Focusing on B2B market, this paper studies the effect of product differentiation on business model perlbrmance. After interviewing several experts and analyzing numbers of distributing questionnaires. the author discovered that product differentiation has a positive effect on business model performance. Through SEM. it is revealed that product differentiation at each level have positive effect on business model, with different effect weight. The main contributions of this research are summarized as follows: Firstly, the proposed model of the product differentiation on business model performance lays the basis for scientific measurement of product differentiation and its effect on business model performance; Secondly, this research ranks the importance of product differentiation at different level in B2B market; Finally, this research provides a good reference for enterprises to update their product strategy for better business model performance.
基金supported by China National Funds for Distinguished Young Scientists(Grant No.61125101)the Science and Technology on Vacuum&Cryogenics Technology and Physics Laboratory
文摘Carbon nanotubes(CNTs)were grown into anodic aluminum oxide(AAO)channels by chemical vapor deposition(CVD)using C2H2/N2mixtures as feeding gas,which can be used as field emitters.The bottom surface of AAO template was etched slightly and the tips of CNTs were explored as the field emission arrays which were uniform and vertical.Field emission characterization showed a low turn-on field about 3.25 V/m and high emission current about 30 mA/cm2with the electric field about 4 V/m.These superior field emission characteristics could be attributed to low density of vertical CNTs and higher conductivity of the substrate.
基金supported by the National Natural Science Foundation of China (Grant No.30901018)the China Postdoctoral Science Foundation (Grant No.201003388)
文摘Engineered sequence-specific zinc finger nucleases (ZFNs) make the highly efficient modification of eukaryotic genomes possible.However,most current strategies for developing zinc finger nucleases with customized sequence specificities require the construction of numerous tandem arrays of zinc finger proteins (ZFPs),and subsequent largescale in vitro validation of their DNA binding affinities and specificities via bacterial selection.The labor and expertise required in this complex process limits the broad adoption of ZFN technology.An effective computational assisted design strategy will lower the complexity of the production of a pair of functional ZFNs.Here we used the FoldX force field to build 3D models of 420 ZFP-DNA complexes based on zinc finger arrays developed by the Zinc Finger Consortium using OPEN (oligomerized pool engineering).Using nonlinear and linear regression analysis,we found that the calculated protein-DNA binding energy in a modeled ZFP-DNA complex strongly correlates to the failure rate of the zinc finger array to show significant ZFN activity in human cells.In our models,less than 5% of the three-finger arrays with calculated protein-DNA binding energies lower than 13.132 kcal mol 1 fail to form active ZFNs in human cells.By contrast,for arrays with calculated protein-DNA binding energies higher than 5 kcal mol 1,as many as 40% lacked ZFN activity in human cells.Therefore,we suggest that the FoldX force field can be useful in reducing the failure rate and increasing efficiency in the design of ZFNs.
基金supported by Advanced Research Center Program(No.2013073861) through the National Research Foundation of Korea
文摘A comparative study with kerosene and hydrogen fuel in a model scramjet combustor has been carried out nu- merically. The effect of fuel-air equivalence ratio on the flow field properties in a cavity based mixing mechanism at a freestream Math number of 2.08 has been probed. The investigation has been carried out in a two dimension- al numerical model where a cavity of length to depth ratio of 2 is mounted on one of the walls of the flow channel The flow field shock structure is observed to change with the change in fuel-air equivalence ratio. Total pressure loss is observed to depend both on fuel air equivalence ratio and the fuel type. The spread of fuel in the test sec- tion shows marked variation with the equivalence ratio. Performance of injector location on the fuel-air mixing is also probed during the course of the investigation.