采用三种不同的预处理工艺对NiTi合金基体进行活化处理,利用柠檬酸作为缓冲剂配制高浓度模拟体液(Simulated body fluid,SBF)5×SBF1和5×SBF2,通过仿生合成在预处理后的NiTi合金基体上快速形成了钙磷涂层。对钙磷涂层的显微结...采用三种不同的预处理工艺对NiTi合金基体进行活化处理,利用柠檬酸作为缓冲剂配制高浓度模拟体液(Simulated body fluid,SBF)5×SBF1和5×SBF2,通过仿生合成在预处理后的NiTi合金基体上快速形成了钙磷涂层。对钙磷涂层的显微结构、组成和形貌进行了研究,结果表明:涂层呈多孔网状,由直径小于3μm的球形颗粒堆积而成,X射线衍射(XRD)测试显示其主要成分为羟基磷灰石;而缺少晶体生长抑制剂Mg2+和HCO3-的5×SBF高浓度模拟体液则明显地加快了羟基磷灰石涂层的形成。展开更多
Based on the convection and diffusion mechanisms of radon migration, in this paper we deduce the two-dimensional differential equation for radon transportation in the overburden above active fault zones with an unlimi...Based on the convection and diffusion mechanisms of radon migration, in this paper we deduce the two-dimensional differential equation for radon transportation in the overburden above active fault zones with an unlimited extension along the strike. Making use of the finite difference method, the radon concentration distribution in the overburden above active faults is calculated and modeled. The active fault zone parameters, such as the depth and the width of the fault zone, and the value of radon concentration, can be inverted from the measured radon concentration curve. These realize quantitative interpretation for radon concentration anomalies. The inversion results are in good agreement with the actual fault zone parameters.展开更多
Objective: To study the pharmacokinetics of 20(R)-Ginsenoside Rg3 in the human body. Methods: High-performance liquid chromatography-ultraviolet detection method was used in this study. Results: The pharmacokinetics o...Objective: To study the pharmacokinetics of 20(R)-Ginsenoside Rg3 in the human body. Methods: High-performance liquid chromatography-ultraviolet detection method was used in this study. Results: The pharmacokinetics of Ginsenoside Rg3 in 14 healthy volunteers were investigated. After a single oral dose of 3.2 mg.g-1 Ginsenoside Rg3 in 8 male volunteers, the plasma concentration-time course fitted in well with a two-compartment open model, with the following pharmacokinetic parameters: Tmax 0.660.10 h, Cmax 166 ngmL-1, T1/2a 0.460.12 h, T1/2b 4.91.1 h, T1/2(Ka) 0.280.04 h, AUC0-∞ 7726 ngmL-1h, respectively. No kinetic analysis was made after an oral dose of 0.8 mg.g-1 Rg3 in other 6 volunteers because of the low concentration, but there was a good correlation between Cmax and dosage of the two groups. Conclusion: The absorption of Rg3 was rapid in the human body, and its elimination was rapid too after oral administration of Ginsenoside Rg3. The pharmacokinetic results shows that it exhibited the first-order kinetic characteristics.展开更多
文摘采用三种不同的预处理工艺对NiTi合金基体进行活化处理,利用柠檬酸作为缓冲剂配制高浓度模拟体液(Simulated body fluid,SBF)5×SBF1和5×SBF2,通过仿生合成在预处理后的NiTi合金基体上快速形成了钙磷涂层。对钙磷涂层的显微结构、组成和形貌进行了研究,结果表明:涂层呈多孔网状,由直径小于3μm的球形颗粒堆积而成,X射线衍射(XRD)测试显示其主要成分为羟基磷灰石;而缺少晶体生长抑制剂Mg2+和HCO3-的5×SBF高浓度模拟体液则明显地加快了羟基磷灰石涂层的形成。
文摘Based on the convection and diffusion mechanisms of radon migration, in this paper we deduce the two-dimensional differential equation for radon transportation in the overburden above active fault zones with an unlimited extension along the strike. Making use of the finite difference method, the radon concentration distribution in the overburden above active faults is calculated and modeled. The active fault zone parameters, such as the depth and the width of the fault zone, and the value of radon concentration, can be inverted from the measured radon concentration curve. These realize quantitative interpretation for radon concentration anomalies. The inversion results are in good agreement with the actual fault zone parameters.
文摘Objective: To study the pharmacokinetics of 20(R)-Ginsenoside Rg3 in the human body. Methods: High-performance liquid chromatography-ultraviolet detection method was used in this study. Results: The pharmacokinetics of Ginsenoside Rg3 in 14 healthy volunteers were investigated. After a single oral dose of 3.2 mg.g-1 Ginsenoside Rg3 in 8 male volunteers, the plasma concentration-time course fitted in well with a two-compartment open model, with the following pharmacokinetic parameters: Tmax 0.660.10 h, Cmax 166 ngmL-1, T1/2a 0.460.12 h, T1/2b 4.91.1 h, T1/2(Ka) 0.280.04 h, AUC0-∞ 7726 ngmL-1h, respectively. No kinetic analysis was made after an oral dose of 0.8 mg.g-1 Rg3 in other 6 volunteers because of the low concentration, but there was a good correlation between Cmax and dosage of the two groups. Conclusion: The absorption of Rg3 was rapid in the human body, and its elimination was rapid too after oral administration of Ginsenoside Rg3. The pharmacokinetic results shows that it exhibited the first-order kinetic characteristics.
