目的比较横开口法与纵开口法经口内镜下肌切开术(POEM)治疗贲门失弛缓症(AC)病人的手术效率和安全性。方法分析2010年12月~2012年09 月间在我院行POEM术的53例AC患者的临床资料,包括患者一般情况,手术相关时间、并发症发生情况等...目的比较横开口法与纵开口法经口内镜下肌切开术(POEM)治疗贲门失弛缓症(AC)病人的手术效率和安全性。方法分析2010年12月~2012年09 月间在我院行POEM术的53例AC患者的临床资料,包括患者一般情况,手术相关时间、并发症发生情况等资料。结果53例患者均顺利完成POEM,其中横开口法组41例,纵开口法12例,平均随访5月(3~24月),症状缓解率96.2%(51/53)。术后Eckardt评分较术前明显改善(7.5 vs 0.6,P〈0.05)。横开口组手术用时65.0±18.0 min,略快于纵开口组74.1±18.2 min,但在隧道建立和环形肌切开过程中,明显快于纵开口法组36.3±9.0 min vs 45.4±10.5 min;10.2±4.6 min vs 15.5±5.5 min P〈0.05)。同时,横开口组在皮下积气等气体相关并发症发生率低于纵开口法组(9.8%(4/41) vs 41.7%(5/12) P〈0.05)。横开口组中另有4例术中发生黏膜穿孔(4/41,9.8%)。4例内镜下有反流性食管炎表现(4/537.5%),LA-A、 LA-B级各2例,其中1例无明显症状。两组均无均无胸腔积液,出血,纵膈炎及消化道瘘等并发症的发生。结论横开口法POEM不仅有效显著缓解患者症状,且更能缩短手术时间,降低皮下气肿、气胸等气体相关并发症的发生率。展开更多
Flows through an open cross-flow-type nano-hydraulic turbine are numerically simulated to investigate the effects of the clearance Hc between the rotor and the ground on the turbine performance. A two-dimensional part...Flows through an open cross-flow-type nano-hydraulic turbine are numerically simulated to investigate the effects of the clearance Hc between the rotor and the ground on the turbine performance. A two-dimensional particle method is employed, which was successfully used for flow simulations of impulse-type and open cross-flow-type nano-hydraulic turbines in the authors' previous works. When the clearance Hc is smaller than a critical value, the simulated turbine performance decreases with decreasing Hc, in good agreement with the experiment. The simulations make it clear that such a reduction of turbine performance is attributable to an increase in the circumferential component of the water velocity at the rotor outlet. The simulations also demonstrate that the effect of the tip speed ratio of the rotor on the relation between Hc and turbine performance can be analyzed.展开更多
文摘目的比较横开口法与纵开口法经口内镜下肌切开术(POEM)治疗贲门失弛缓症(AC)病人的手术效率和安全性。方法分析2010年12月~2012年09 月间在我院行POEM术的53例AC患者的临床资料,包括患者一般情况,手术相关时间、并发症发生情况等资料。结果53例患者均顺利完成POEM,其中横开口法组41例,纵开口法12例,平均随访5月(3~24月),症状缓解率96.2%(51/53)。术后Eckardt评分较术前明显改善(7.5 vs 0.6,P〈0.05)。横开口组手术用时65.0±18.0 min,略快于纵开口组74.1±18.2 min,但在隧道建立和环形肌切开过程中,明显快于纵开口法组36.3±9.0 min vs 45.4±10.5 min;10.2±4.6 min vs 15.5±5.5 min P〈0.05)。同时,横开口组在皮下积气等气体相关并发症发生率低于纵开口法组(9.8%(4/41) vs 41.7%(5/12) P〈0.05)。横开口组中另有4例术中发生黏膜穿孔(4/41,9.8%)。4例内镜下有反流性食管炎表现(4/537.5%),LA-A、 LA-B级各2例,其中1例无明显症状。两组均无均无胸腔积液,出血,纵膈炎及消化道瘘等并发症的发生。结论横开口法POEM不仅有效显著缓解患者症状,且更能缩短手术时间,降低皮下气肿、气胸等气体相关并发症的发生率。
文摘Flows through an open cross-flow-type nano-hydraulic turbine are numerically simulated to investigate the effects of the clearance Hc between the rotor and the ground on the turbine performance. A two-dimensional particle method is employed, which was successfully used for flow simulations of impulse-type and open cross-flow-type nano-hydraulic turbines in the authors' previous works. When the clearance Hc is smaller than a critical value, the simulated turbine performance decreases with decreasing Hc, in good agreement with the experiment. The simulations make it clear that such a reduction of turbine performance is attributable to an increase in the circumferential component of the water velocity at the rotor outlet. The simulations also demonstrate that the effect of the tip speed ratio of the rotor on the relation between Hc and turbine performance can be analyzed.