期刊文献+
共找到3篇文章
< 1 >
每页显示 20 50 100
梵净山土壤来源链霉菌Streptomyces sp.FJS11-2次级代谢产物分析及抗菌活性研究
1
作者 李彩玉 钱声艳 秦立达 《云南民族大学学报(自然科学版)》 CAS 2018年第5期372-376,共5页
为了分析链霉菌Streptomyces sp. FJS11-2菌株次级代谢产物及次级代谢产物抗菌活性筛选,采用UPLC-DAD-HRMS方法对其次级代谢产物进行组分分析.用纸片扩散法对菌株次级代谢产物进行抗菌活性测试,测试菌株为金黄色葡萄球菌、大肠杆菌、白... 为了分析链霉菌Streptomyces sp. FJS11-2菌株次级代谢产物及次级代谢产物抗菌活性筛选,采用UPLC-DAD-HRMS方法对其次级代谢产物进行组分分析.用纸片扩散法对菌株次级代谢产物进行抗菌活性测试,测试菌株为金黄色葡萄球菌、大肠杆菌、白色念珠菌、粪肠球菌及布氏杆菌. UPLC-DAD-HRMS分析结果表明,该菌株含有多种未知代谢产物.且抗菌活性研究结果表明,该菌株代谢产物具有抗金黄色葡萄球菌、布氏杆菌活性. UPLC-DAD-HRMS分析结果及抗菌活性结果,为后续从该菌株次级代谢产物中发现活性良好、结构新颖的化学成分奠定基础,同时该方法也避免化学成分重复发现. 展开更多
关键词 链霉菌Streptomyces sp. FJS11-2 次级代谢产物分析 抗菌活性测试
下载PDF
红曲菌转化库中部分突变子的次级代谢产物分析
2
作者 王斌 《生物技术世界》 2012年第1期14-15,共2页
本文采用TLC、HPLC、ELISA等方法测定了12株红曲转化子MonacolinK、γ-氨基丁酸和桔霉素的含量。结果表明,与出发菌株P-4相比,突变株产次级代谢产物的能力都发生了不同程度的变化。8株突变菌株红曲的MonacolinK含量高于P-4,其中1121#的M... 本文采用TLC、HPLC、ELISA等方法测定了12株红曲转化子MonacolinK、γ-氨基丁酸和桔霉素的含量。结果表明,与出发菌株P-4相比,突变株产次级代谢产物的能力都发生了不同程度的变化。8株突变菌株红曲的MonacolinK含量高于P-4,其中1121#的MonacolinK含量约为P-4的10倍,分别为542.13μg/g和58.65μg/g;GABA含量方面,以779#制备的红曲GABA含量最高,达1.165g/Kg,约为P-4的3倍;由167#制备的红曲的桔霉素含量最高,为65.71ng/g,而2107#与779#制备的红曲的桔霉素含量在实验条件下未检测到。 展开更多
关键词 红曲菌、次级代谢产物分析
原文传递
Effects of ecological factors on secondary metabolites and inorganic elements of Scutellaria baicalensis and analysis of geoherblism 被引量:10
3
作者 GUO LanPing WANG Sheng +8 位作者 ZHANG Ji YANG Guang ZHAO ManXi MA WeiFeng ZHANG XiaoBo LI Xuan HAN BangXing CHEN NaiFu HUANG LuQi 《Science China(Life Sciences)》 SCIE CAS 2013年第11期1047-1056,共10页
This study analyzed the effects of ecological factors on secondary metabolites of Scutellaria baicalensis using two sources:92individual roots of S.baicalensis from all over China,and secondary metabolites,medicinal m... This study analyzed the effects of ecological factors on secondary metabolites of Scutellaria baicalensis using two sources:92individual roots of S.baicalensis from all over China,and secondary metabolites,medicinal materials and inorganic element contents obtained from the testing of 92 S.baicalensis rhizosphere soil samples.The study used environmental data from the Genuine Medicinal Material Spatial Analysis Database.Most of the chemical constituents of S.baicalensis were negatively correlated to latitude and positively correlated to temperature;generally,the contents of 21 chemical constituents were higher at low latitudes than that at high latitudes.By gradual regression analysis,it was found that the content of baicalin in S.baicalensis was negatively correlated to latitude and generally the content of inorganic elements in soil was excessively high(excluding Mg and Ca),which has a negative effect on the accumulation of chemical constituents in S.baicalensis.Based on the cluster analysis of 21 constituents,S.baicalensis from different places of origin was divided into two groups,and S.baicalensis was not genuine only in a specific small region.Within the zone from Chifeng,Inner Mongolia to Taibai,Shaanxi is suitable for accumulation of secondary metabolites of S.baicalensis and such a zone represents a suitable distribution and potential genuine producing area. 展开更多
关键词 Scutellaria baicalensis ecological factors geoherbs Daodi-herbs geographical variation
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部