Objective To observe the clinical application value of total free-breathing cardiac MR(CMR)examination preliminarily.Methods Two patients who underwent CMR scanning under free-breathing state,including cine,motion cor...Objective To observe the clinical application value of total free-breathing cardiac MR(CMR)examination preliminarily.Methods Two patients who underwent CMR scanning under free-breathing state,including cine,motion correction T1 and T2 mapping,blood flow imaging,and late gadolinium enhancement scanning were retrospectively enrolled,and the qualities of the above images were evaluated and compared with that of conventional CMR images under breath-holding state.Results No significant difference of imaging quality was found between total free-breathing and conventional breath-holding CMR.The differences of left ventricular ejection fraction,cardiac output,left ventricular end-diastolic volume index and left ventricular mass measured based on CMR images under different breath conditions were limited.Conclusion Total free-breathing CMR was feasible in clinical practice,which could provide"one-stop"evaluation of cardiac structure,function and myocardial histological characteristics,hence having promising clinical prospects.展开更多
Objective To observe the efficacy of deep learning(DL)model based on PET/CT and its combination with Cox proportional hazard model for predicting progressive disease(PD)of lung invasive adenocarcinoma within 5 years a...Objective To observe the efficacy of deep learning(DL)model based on PET/CT and its combination with Cox proportional hazard model for predicting progressive disease(PD)of lung invasive adenocarcinoma within 5 years after surgery.Methods The clinical,PET/CT and 5-year follow-up data of 250 patients with lung invasive adenocarcinoma were retrospectively analyzed.According to PD or not,the patients were divided into the PD group(n=71)and non-PD group(n=179).The basic data and PET/CT findings were compared between groups,among which the quantitative variables being significant different between groups were transformed to categorical variables using receiver operating characteristic(ROC)curve and corresponding cut-off value.Multivariant Cox proportional hazard model was used to select independent predicting factors of PD of lung invasive adenocarcinoma within 5 years after surgery.The patients were divided into training,validation and test sets at the ratio of 6∶2∶2,and PET/CT data in training set and validation set were used to train model and tuning parameters to build the PET/CT DL model,and the combination model was built in serial connection of DL model and the predictive factors.In test set,the efficacy of each model for predicting PD of lung invasive adenocarcinoma within 5 years after surgery was assessed and compared using the area under the curve(AUC).Results Patients'gender and smoking status,as well as the long diameter,SUV max and SUV mean of lesions measured on PET images,the long diameter,short diameter and type of lesions showed on CT were statistically different between groups(all P<0.05).Smoking(HR=1.787[1.053,3.031],P=0.031)and lesion SUV max>4.15(HR=5.249[1.062,25.945],P=0.042)were both predictors of PD of lung invasive adenocarcinoma within 5 years after surgery.In test set,the AUC of PET/CT DL model for predicting PD was 0.847,of the combination model was 0.890,of the latter was higher than of the former(P=0.036).Conclusion DL model based on PET/CT had high efficacy for predicting PD of lung invasive adenocarcinoma within 5 years after surgery.Combining with Cox proportional hazard model could further improve its predicting efficacy.展开更多
A design strategy for a research platform of a telepresence telerobot system based on virtual reality technology is put forward. The design frame of the system is described, and its important core techniques are descr...A design strategy for a research platform of a telepresence telerobot system based on virtual reality technology is put forward. The design frame of the system is described, and its important core techniques are described. An octrees data structure is utilized to build kinematic and dynamic modeling of the virtual simulation environment, Delphi+OpenGL+3DS MAX are adopted to carry through the virtual modeling and visible simulation exploitation of the slave-robot and its environment. Photo-correction is adopted to correct positioning deviation of the virtual geometric model and modeling errors. The cost of software and hardware equipment for the research platform realized is low. The master/slave robot (manipulator) system and all software in the system were designed and manufactured by our research group. The performance of the system has reached the level required for research. An indispensable experiment base is provided for the research of a telepresence telerobot system based on virtual reality technology.展开更多
Static corrections using the conventional method are basically conducted in two steps, the weathering correction followed by the correction from the top of the sub-weathering to the unified datum. However, the convent...Static corrections using the conventional method are basically conducted in two steps, the weathering correction followed by the correction from the top of the sub-weathering to the unified datum. However, the conventional method fails to well deal with statics problems in case the top of the sub-weathering is sharply undulated and the lateral velocity of the sub-weathering varies significantly. This brings us to the introduction of a smooth intermediate reference datum （IRD） located under the top of the sub-weathering, which helps to further increase the accuracy of statics based on the weathering corrections, and ensures the imaging quality. Good results based on the IRD technique have been achieved in the complex areas in western China. This paper discusses the IRD functions, its application requirements, and selection of related parameters. Some typical sections for comparison are also given in this paper.展开更多
To solve the problem that metal artifacts severely damage the clarity of the organization structure in computed tomography（CT） images, a sinogram fusion-based metal artifact correction method is proposed. First, the...To solve the problem that metal artifacts severely damage the clarity of the organization structure in computed tomography（CT） images, a sinogram fusion-based metal artifact correction method is proposed. First, the metal image is segmented from the original CT image by the pre-set threshold. The original CT image and metal image are forward projected into the original projection sinogram and metal projection sinogram, respectively. The interpolation-based correction method and mean filter are used to correct the original CT image and preserve the edge of the corrected CT image, respectively. The filtered CT image is forward projected into the filtered image sinogram. According to the position of the metal sinogram in the original sinogram and filtered image sinogram, the corresponding sinograms PM^D （ in the original sinogram） and PM^C （ in the filtered image sinogram）can be acquired from the original sinogram and filtered image sinogram, respectively. Then, PM^D and PM^C are fused into the fused metal sinogram PM^F according to a certain proportion.The final sinogram can be acquired by fusing PM^F , PM^D and the original sinogram P^O. Finally, the final sinogram is reconstructed into the corrected CT image and metal information is compensated into the corrected CT image.Experiments on clinical images demonstrate that the proposed method can effectively reduce metal artifacts. A comparison with classical metal artifacts correction methods shows that the proposed metal artifacts correction method performs better in metal artifacts suppression and tissue feature preservation.展开更多
To alleviate the distortion of XRII X-ray image intensifier images in the C-arm CT computer tomography imaging system an algorithm based on the Delaunay triangulation interpolation is proposed.First the causes of the ...To alleviate the distortion of XRII X-ray image intensifier images in the C-arm CT computer tomography imaging system an algorithm based on the Delaunay triangulation interpolation is proposed.First the causes of the phenomenon the classical correction algorithms and the Delaunay triangulation interpolation are analyzed.Then the algorithm procedure is explained using flow charts and illustrations. Finally experiments are described to demonstrate its effectiveness and feasibility. Experimental results demonstrate that the Delaunay triangulation interpolation can have the following effects.In the case of the same center the root mean square distances RMSD and standard deviation STD between the corrected image with Delaunay triangulation interpolation and the ideal image are 5.760 4 ×10 -14 and 5.354 2 ×10 -14 respectively.They increase to 1.790 3 2.388 8 2.338 8 and 1.262 0 1.268 1 1.202 6 after applying the quartic polynomial model L1 and model L2 to the distorted images respectively.The RMSDs and STDs between the corrected image with the Delaunay triangulation interpolation and the ideal image are 2.489 × 10 -13 and 2.449 8 ×10 -13 when their centers do not coincide. When the quartic polynomial model L1 and model L2 are applied to the distorted images they are 1.770 3 2.388 8 2.338 8 and 1.269 9 1.268 1 1.202 6 respectively.展开更多
文摘Objective To observe the clinical application value of total free-breathing cardiac MR(CMR)examination preliminarily.Methods Two patients who underwent CMR scanning under free-breathing state,including cine,motion correction T1 and T2 mapping,blood flow imaging,and late gadolinium enhancement scanning were retrospectively enrolled,and the qualities of the above images were evaluated and compared with that of conventional CMR images under breath-holding state.Results No significant difference of imaging quality was found between total free-breathing and conventional breath-holding CMR.The differences of left ventricular ejection fraction,cardiac output,left ventricular end-diastolic volume index and left ventricular mass measured based on CMR images under different breath conditions were limited.Conclusion Total free-breathing CMR was feasible in clinical practice,which could provide"one-stop"evaluation of cardiac structure,function and myocardial histological characteristics,hence having promising clinical prospects.
文摘Objective To observe the efficacy of deep learning(DL)model based on PET/CT and its combination with Cox proportional hazard model for predicting progressive disease(PD)of lung invasive adenocarcinoma within 5 years after surgery.Methods The clinical,PET/CT and 5-year follow-up data of 250 patients with lung invasive adenocarcinoma were retrospectively analyzed.According to PD or not,the patients were divided into the PD group(n=71)and non-PD group(n=179).The basic data and PET/CT findings were compared between groups,among which the quantitative variables being significant different between groups were transformed to categorical variables using receiver operating characteristic(ROC)curve and corresponding cut-off value.Multivariant Cox proportional hazard model was used to select independent predicting factors of PD of lung invasive adenocarcinoma within 5 years after surgery.The patients were divided into training,validation and test sets at the ratio of 6∶2∶2,and PET/CT data in training set and validation set were used to train model and tuning parameters to build the PET/CT DL model,and the combination model was built in serial connection of DL model and the predictive factors.In test set,the efficacy of each model for predicting PD of lung invasive adenocarcinoma within 5 years after surgery was assessed and compared using the area under the curve(AUC).Results Patients'gender and smoking status,as well as the long diameter,SUV max and SUV mean of lesions measured on PET images,the long diameter,short diameter and type of lesions showed on CT were statistically different between groups(all P<0.05).Smoking(HR=1.787[1.053,3.031],P=0.031)and lesion SUV max>4.15(HR=5.249[1.062,25.945],P=0.042)were both predictors of PD of lung invasive adenocarcinoma within 5 years after surgery.In test set,the AUC of PET/CT DL model for predicting PD was 0.847,of the combination model was 0.890,of the latter was higher than of the former(P=0.036).Conclusion DL model based on PET/CT had high efficacy for predicting PD of lung invasive adenocarcinoma within 5 years after surgery.Combining with Cox proportional hazard model could further improve its predicting efficacy.
文摘A design strategy for a research platform of a telepresence telerobot system based on virtual reality technology is put forward. The design frame of the system is described, and its important core techniques are described. An octrees data structure is utilized to build kinematic and dynamic modeling of the virtual simulation environment, Delphi+OpenGL+3DS MAX are adopted to carry through the virtual modeling and visible simulation exploitation of the slave-robot and its environment. Photo-correction is adopted to correct positioning deviation of the virtual geometric model and modeling errors. The cost of software and hardware equipment for the research platform realized is low. The master/slave robot (manipulator) system and all software in the system were designed and manufactured by our research group. The performance of the system has reached the level required for research. An indispensable experiment base is provided for the research of a telepresence telerobot system based on virtual reality technology.
文摘Static corrections using the conventional method are basically conducted in two steps, the weathering correction followed by the correction from the top of the sub-weathering to the unified datum. However, the conventional method fails to well deal with statics problems in case the top of the sub-weathering is sharply undulated and the lateral velocity of the sub-weathering varies significantly. This brings us to the introduction of a smooth intermediate reference datum （IRD） located under the top of the sub-weathering, which helps to further increase the accuracy of statics based on the weathering corrections, and ensures the imaging quality. Good results based on the IRD technique have been achieved in the complex areas in western China. This paper discusses the IRD functions, its application requirements, and selection of related parameters. Some typical sections for comparison are also given in this paper.
基金Open Research Fund of the Key Laboratory of Computer Netw ork and Information Integration of Ministry of Education of Southeast University(No.K93-9-2014-10C)the Scientific Research Foundation of Education Department of Anhui Province(No.KJ2014A186,SK2015A433)the National Basic Research Program of China(973 Program)(No.2010CB732503)
文摘To solve the problem that metal artifacts severely damage the clarity of the organization structure in computed tomography（CT） images, a sinogram fusion-based metal artifact correction method is proposed. First, the metal image is segmented from the original CT image by the pre-set threshold. The original CT image and metal image are forward projected into the original projection sinogram and metal projection sinogram, respectively. The interpolation-based correction method and mean filter are used to correct the original CT image and preserve the edge of the corrected CT image, respectively. The filtered CT image is forward projected into the filtered image sinogram. According to the position of the metal sinogram in the original sinogram and filtered image sinogram, the corresponding sinograms PM^D （ in the original sinogram） and PM^C （ in the filtered image sinogram）can be acquired from the original sinogram and filtered image sinogram, respectively. Then, PM^D and PM^C are fused into the fused metal sinogram PM^F according to a certain proportion.The final sinogram can be acquired by fusing PM^F , PM^D and the original sinogram P^O. Finally, the final sinogram is reconstructed into the corrected CT image and metal information is compensated into the corrected CT image.Experiments on clinical images demonstrate that the proposed method can effectively reduce metal artifacts. A comparison with classical metal artifacts correction methods shows that the proposed metal artifacts correction method performs better in metal artifacts suppression and tissue feature preservation.
基金The Natural Science Foundation of Anhui Province(No.1308085MF96)the Project of Chuzhou University(No.2012qd06,2011kj010B)+1 种基金the Scientific Research Foundation of Education Department of Anhui Province(No.KJ2014A186)the National Basic Research Program of China(973 Program)(No.2010CB732503)
文摘To alleviate the distortion of XRII X-ray image intensifier images in the C-arm CT computer tomography imaging system an algorithm based on the Delaunay triangulation interpolation is proposed.First the causes of the phenomenon the classical correction algorithms and the Delaunay triangulation interpolation are analyzed.Then the algorithm procedure is explained using flow charts and illustrations. Finally experiments are described to demonstrate its effectiveness and feasibility. Experimental results demonstrate that the Delaunay triangulation interpolation can have the following effects.In the case of the same center the root mean square distances RMSD and standard deviation STD between the corrected image with Delaunay triangulation interpolation and the ideal image are 5.760 4 ×10 -14 and 5.354 2 ×10 -14 respectively.They increase to 1.790 3 2.388 8 2.338 8 and 1.262 0 1.268 1 1.202 6 after applying the quartic polynomial model L1 and model L2 to the distorted images respectively.The RMSDs and STDs between the corrected image with the Delaunay triangulation interpolation and the ideal image are 2.489 × 10 -13 and 2.449 8 ×10 -13 when their centers do not coincide. When the quartic polynomial model L1 and model L2 are applied to the distorted images they are 1.770 3 2.388 8 2.338 8 and 1.269 9 1.268 1 1.202 6 respectively.
