牛蒡子口腔崩解片的处方研究

目的确定牛蒡子口腔崩解片的处方。方法采用正交设计法选择牛蒡子口腔崩解片的处方。结果确定牛蒡子口腔崩解片处方中主要的成分配比为:交联聚乙烯吡咯烷酮8%,微晶纤维素25%,α-乳糖25%。结论确定了牛蒡子口腔崩解片的处方,但是此片剂口感一般,须进一步研究。

菜籽饼粕中多糖的酸提取工艺优化

采用五因子二次正交旋转设计，研究酸浓度、料液比、提取时间、提取温度、提取次数等5个因素对酸提取菜籽饼粕中多糖的得率的影响，用SAS8．0中响应面分析程序RSREG建立并分析了5个因素对得率的函数模型。结果表明，所得回归方程达显著水平，拟合情况良好;5个因素对得率的影响大小依次为提取温度〉提取次数〉提取时间〉酸浓度〉料液比，最佳提取温度为100℃，提取次数4～5次，提取时间（每次）1．4～1．8h，酸浓度0．10～0．14mol／L，料液比1：18～1：22，菜籽饼粕多糖得率在3．1％以上。

Optimization of the Conditions of SRAP Molecular Marker Used in Analysis of Fagopyrum tataricum

[Objective] The aim was to investigate the optimal conditions of SRAP molecular marker used in the analysis on Fagopyrum tataricum（L.）Gaertn.[Method]SRAP-PCR amplification system on Fagopyrum tataricum was optimized by interactive orthogonal design L27（313）in 5 elements（Mg2＋,dNTP,Taq DNA polymerase,template DNA and primer）at 3 levels.And the non-denaturing and denaturing PAGE detection methods were compared.The comparative test of DYCZ-24F and DYCZ-20C electrophoresis operating systems was carried out.[Result]The effects of four single-factor（Mg2＋,dNTP,Taq DNA polymerase and primer）and two interactions（Mg2＋×dNTP,Mg2＋×Taq DNA polymerase）on tartary buckwheat SRAP-PCR were significant.An optimal reaction system was established containing 1.5 mmol/L Mg2＋,0.2 mmol/L dNTP,1.5 u Taq DNA polymerase,40 ng DNA,0.25 μmol/L primer and 2 μl 10×buffer.Seven samples of tartary buckwheat were amplified using this system,and electrophoresis results showed clear bands,high level of polymorphism and good reproducibility.The PCR products were tested by denaturing and non-denaturing PAGE,and the results showed that the non-denaturing PAGE,DYCZ-24F operating system was more suitable for SRAP analysis.[Conclusion]This study established a foundation for the construction of SRAP genetic map of tartary buckwheat.

Influence of radial forging process on strain inhomogeneity of hollow gear shaft using finite element method and orthogonal design

Due to the current trend towards lightweight design in automotive industry,hollow stepped gear shafts for automobile and its radial forging process are widely investigated.Utilizing coupled finite element thermo-mechanical model,radial forging process of a hollow stepped gear shaft for automobile was simulated.The optimal combination of three process parameters including initial temperature,rotation rate and radial reduction was also selected using orthogonal design method.To examine the strain inhomogeneity of the forging workpiece,the strain inhomogeneity factor was introduced.The results reveal that the maximum effective strain and the minimum effective strain appeared in the outermost and innermost zones of different cross sections for the hollow stepped gear shaft,respectively.Optimal forging parameters are determined as a combination of initial temperature of 780°C,rotation rate of 21°/stroke and radial reduction of 3 mm.

Walsh Hadamard Transform Based Transceiver Design for SC-FDMA with Discrete Wavelet Transform

This article proposes a new transceiver design for Single carrier frequency division multiple access(SCFDMA)system based on discrete wavelet transform(DWT). SCFDMA offers almost same structure as Orthogonal frequency division multiple access(OFDMA)with extra advantage of low Peak to Average Power Ratio(PAPR). Moreover,this article also suggests the application of Walsh Hadamard transform(WHT)for linear precoding(LP)to improve the PAPR performance of the system. Supremacy of the proposed transceiver over conventional Fast Fourier transform(FFT)based SCFDMA is shown through simulated results in terms of PAPR,spectral efficiency(SE)and bit error rate(BER).

Design and application of electric oil pump in automatic transmission for efficiency improvement and start–stop function

For the purpose of improving efficiency and realizing start–stop function, an electric oil pump(EOP) is integrated into an 8-speed automatic transmission(AT). A mathematical model is built to calculate the transmission power loss and the hydraulic system leakage. Based on this model, a flow-based control strategy is developed for EOP to satisfy the system flow requirement. This control strategy is verified through the forward driving simulation. The results indicate that there is a best combination for the size of mechanical oil pump(MOP) and EOP in terms of minimum energy consumption. In order to get a quick and smooth starting process, control strategies of the EOP and the on-coming clutch are proposed. The test environment on a prototype vehicle is built to verify the feasibility of the integrated EOP and its control strategies. The results show that the selected EOP can satisfy the flow requirement and a quick and smooth starting performance is achieved in the start–stop function. This research has a high value for the forward design of EOP in automatic transmissions with respect to efficiency improvement and start–stop function.

Strain and Culture Medium Optimization for Production Enhancement of Prodiginines from Marine-Derived Streptomyces sp. GQQ-10

A mutant (GQQ-M6) of a Sponge-Derived streptomyces sp. GQQ-10 obtained by UV-induced mutation was used for producing prodiginines (PGs). Single factor experiments and orthogonal array design (OAD) methods were employed for medium optimization. In the single factor method, the effects of soluble starch, glucose, soybean flour, yeast extract and sodium acetate on PGs production were investigated individually. In the subsequent OAD experiments, the concentrations of these 5 key nutritional components combined with salinity were further adjusted. The mutant strain GQQ-M6 gave a 2.2-fold higher PGs production than that of the parent strain; OAD experiments offered a PGs yield of 61mg L-1, which was 10 times higher than that of the initial GQQ-10 strain under the original cultivation mode.