A lot of work has been focused on desig-ning and analyzing various cooperative diversity pro-tocols for wireless relay networks. To provide a uni-fied queuing analytic framework, we fonmlate an em-bedded Markov chain,...A lot of work has been focused on desig-ning and analyzing various cooperative diversity pro-tocols for wireless relay networks. To provide a uni-fied queuing analytic framework, we fonmlate an em-bedded Markov chain, which rams out to be a Quasi-Birth-and-Death （QBD） process. Using the Matrix-Ce-ometric method, we can analyze the average delay in a unified way. Theoretical analysis is validated by simu-lation results. We show that the delay performances of Amplify-and-Forward or Decode-and-Forwaxd （AF/ DF） and incremental AF/DF schemes can be analyzed in the unified way. Thus, we can always choose the best cooperative diversity scheme in different scenari-os for delay minimization.展开更多
DNA double-stranded break(DSB)is one of the most catastrophic damages of genotoxic insult.Inappropriate repair of DNA DSBs results in the loss of genetic information,mutation,and the generation of harmful genomic rear...DNA double-stranded break(DSB)is one of the most catastrophic damages of genotoxic insult.Inappropriate repair of DNA DSBs results in the loss of genetic information,mutation,and the generation of harmful genomic rearrangements,which predisposes an organism to immunodeficiency,neurological damage,and cancer.The tumor repressor p53 plays a key role in DNA damage response,and has been found to be mutated in 50%of human cancer.p53,p63,and p73 are three members of the p53 gene family.Recent discoveries have shown that human p53 gene encodes at least 12 isoforms.Different p53 members and isoforms play various roles in orchestrating DNA damage response to maintain genomic integrity.This review briefly explores the functions of p53 and its isoforms in DNA DSB repair.展开更多
Delay/disruption tolerant networking （DTN） is an approach to networking where intermittent connectivity exists： it is often afforded by a store and forward technique. Depending on the capability of intermediary nod...Delay/disruption tolerant networking （DTN） is an approach to networking where intermittent connectivity exists： it is often afforded by a store and forward technique. Depending on the capability of intermediary nodes to carry and forward messages, messages can be eventually delivered to their destination by mobile nodes with an appropriate routing protocol. To have achieved a successful delivery, most DTN routing protocols use message duplication methods. Although messages are rapidly transferred to the destination, the redundancy in the number of message copies increases rapidly. This paper presents a new routing scheme based on a stochastic process for epidemic routing. Message redundancy is efficiently reduced and the number of message copies is controlled reasonably. During the contact process of nodes in the network, the number of message copies changes, and according to the variability in the number of copies, we construct a special Markov chain, birth and death process, on the number of message copies then calculate and obtain a stationary distribution of the birth and death process. Comparing the theoretical model with the simulation we have performed we see similar results. Our method improves on time-to-live （TTL） and antipacket methods, in both redundancy and delivery success efficiency.展开更多
基金This work was supported by the National Basic Research Program of China under Crant No. 2012CB316001 the National Science Foundation of China under Crants No. （：13832008, No. 03902001.
文摘A lot of work has been focused on desig-ning and analyzing various cooperative diversity pro-tocols for wireless relay networks. To provide a uni-fied queuing analytic framework, we fonmlate an em-bedded Markov chain, which rams out to be a Quasi-Birth-and-Death （QBD） process. Using the Matrix-Ce-ometric method, we can analyze the average delay in a unified way. Theoretical analysis is validated by simu-lation results. We show that the delay performances of Amplify-and-Forward or Decode-and-Forwaxd （AF/ DF） and incremental AF/DF schemes can be analyzed in the unified way. Thus, we can always choose the best cooperative diversity scheme in different scenari-os for delay minimization.
基金supported by the National Natural Science Foundation of China(Nos.31571511 and 31871500)
文摘DNA double-stranded break(DSB)is one of the most catastrophic damages of genotoxic insult.Inappropriate repair of DNA DSBs results in the loss of genetic information,mutation,and the generation of harmful genomic rearrangements,which predisposes an organism to immunodeficiency,neurological damage,and cancer.The tumor repressor p53 plays a key role in DNA damage response,and has been found to be mutated in 50%of human cancer.p53,p63,and p73 are three members of the p53 gene family.Recent discoveries have shown that human p53 gene encodes at least 12 isoforms.Different p53 members and isoforms play various roles in orchestrating DNA damage response to maintain genomic integrity.This review briefly explores the functions of p53 and its isoforms in DNA DSB repair.
文摘Delay/disruption tolerant networking （DTN） is an approach to networking where intermittent connectivity exists： it is often afforded by a store and forward technique. Depending on the capability of intermediary nodes to carry and forward messages, messages can be eventually delivered to their destination by mobile nodes with an appropriate routing protocol. To have achieved a successful delivery, most DTN routing protocols use message duplication methods. Although messages are rapidly transferred to the destination, the redundancy in the number of message copies increases rapidly. This paper presents a new routing scheme based on a stochastic process for epidemic routing. Message redundancy is efficiently reduced and the number of message copies is controlled reasonably. During the contact process of nodes in the network, the number of message copies changes, and according to the variability in the number of copies, we construct a special Markov chain, birth and death process, on the number of message copies then calculate and obtain a stationary distribution of the birth and death process. Comparing the theoretical model with the simulation we have performed we see similar results. Our method improves on time-to-live （TTL） and antipacket methods, in both redundancy and delivery success efficiency.
