Antiretroviral Drug Distribution Routing System in Limpopo Province of South Africa

This study was concerned with developing an antiretroviral drug distribution routing system with a goal of improving fleet utilization whilst reducing delivery costs. The system would enhance ARV drug delivery satisfaction of patients staying in the Limpopo province of South Africa. A VRP mathematical programming problem was formulated and the Savings Based as well as the Sequential Insertion algorithm was used to solve the problem. A mini program was then developed in Visual Basic.Net software that speeded up the vehicle route determination heuristics. This computer based vehicle routing system gave a total travelled distance of 1302.94 km and a space utilization of 93% as compared to the pigeonhole system which had a total travelled distance of 2874.2 km and space utilization of 86% for the demand of 5384 ARV drug patients. Therefore, the mathematical programming approach is more cost effective and efficient thereby enhancing delivery satisfaction to ARV drug patients in the province.

氰化物中毒迟发性死亡法医学分析1例

1案例资料1.1简要案情刘某,男,53岁。因纠纷被人非法拘禁,2d后给朋友打电话诉因遭受＂殴打＂而口服＂氯化钾＂,其友随即报警,30min后送往医院,查体Bp 9.3/5.3kPa（70/40mmHg）,无呼吸及心跳,心肌酶谱示：CK-MB1.2ng/mL,TnI-I 0.009ng/mL,MYO 98.9ng/mL;