Towards a cure for HIV： the identification and characterization of HIV reservoirs in optimally treated people

Currently available anti-HIV-1 drugs suppress viral replication and maintain viral levels below the detection threshold of most assays but do not eliminate cellular reservoirs. As a result, very low levels of circulating virus can be detected in most people despite long-term treatment with potent anti-HIV drug combinations. Not surprisingly, viral levels rebound with discontinuation of treatment. New evidence indicates that there is a viral reservoir in bone marrow progenitor cells.

浮动床膜生物反应器去除焦化废水中间甲酚研究

焦化废水属有毒有害、难降解的高浓度有机废水,其中间甲酚等酚类污染物含量较高且用常用水处理方法去除比较困难。因此,研究了将浮动床生物膜反应器与膜生物反应器进行复合去除焦化废水中间甲酚的影响因素,并与普通MBR反应器在相同间甲酚浓度梯度下的处理功效进行比较。结果表明,在相同间甲酚浓度下,生物浮动床膜生物反应器的处理效果优于普通MBR反应器,其毒阈值为1200 mg/L,普通MBR反应器为1000 mg/L。同时,利用扫描电镜对浮动床膜生物反应器填料上微生物进行观察,考察了间甲酚浓度升高对填料上微生物的影响及附着态微生物形态的变化,得出大型微生物随着间甲酚浓度的提高最后破裂死亡;杆菌种类及数量减少,最后转变成丝状菌;球菌的菌胶团解体,形状变成短杆状。