AIM To investigate the prognostic value of preoperative fbri-nogen concentration (FIB) and D-dimer-fibrinogen ratio (DFR) in gastrointestinal stromal tumors (GISTs).METHODS The purpose of this study was to retro...AIM To investigate the prognostic value of preoperative fbri-nogen concentration (FIB) and D-dimer-fibrinogen ratio (DFR) in gastrointestinal stromal tumors (GISTs).METHODS The purpose of this study was to retrospectively ana-lyze 170 patients with GISTs who were admitted to our hospital from January 2010 to December 2015. The op-timal cutoff values of related parameters were estimated by receiver operating characteristic (ROC) curve analysis. The recurrence free survival (RFS) rate was evaluated using Kaplan-Meier curves. Univariate analysis and multivariate Cox regression models were used to analyze the prognostic factors of GISTs. The relationship between the FIB, D-dimer, DFR, platelet count (PLT), and the clinicopathological features of GISTs was described by the chi-square test or nonparametric rank sum test (Mann-Whitney test).RESULTS In ROC analysis, the optimal cutoff values of FIB, D-dimer, DFR, and PLT were 3.24 g/L, 1.24 mg/L, 0.354, and 197.5 (× 109/L), respectively. Univariate analysis and the Kaplan-Meier survival curve showed that FIB, D-dimer, DFR, PLT,National Institutes of Health (NIH) risk category, tumor size, tumor location, and mitotic index were signifcantly relevant to the 3-year and 5-year survival rate of patients ( P 〈 0.05). Cox multivariate regression analysis illustrated that FIB (RR: 0.108, 95%CI: 0.031-0.373), DFR (RR: 0.319, 95%CI: 0.131-0.777), and NIH risk category ( RR: 0.166, 95%CI: 0.047-0.589) were independent prognostic factors of the RFS rate ( P 〈 0. 05). Moreover, FIB, D-dimer, DFR, and PLT were correlated with the clinical features of GISTs.CONCLUSIONFIB, D-dimer, DFR, and PLT are all related to the prognosis of GISTs. Moreover, FIB and DFR may be independent risk factors for predicting the prognosis of resectable GISTs.展开更多
In this paper,the Gaoyou-Baoying M_S4.9 earthquake was analyzed by the geomagnetic harmonic wave amplitude ratios method. The earthquake was an isolated seismic event,before and after which there were no other earthqu...In this paper,the Gaoyou-Baoying M_S4.9 earthquake was analyzed by the geomagnetic harmonic wave amplitude ratios method. The earthquake was an isolated seismic event,before and after which there were no other earthquakes occurred in this region. The dense distribution of geomagnetic observataries provided an advantage condition for the analysis of characteristics of the geomagnetic harmonic amplitude ratios. The analysis results verify the former knowledge of anomaly characteristics of the geomagnetic harmonic amplitude ratio,that is,the anomalous characteristics of the earthquake mostly appeared during the decline-turning-recovery rising process. The results also show that the change of the anomalies was asynchronous at the observatories close to the epicenter, namely, the anomalous characteristics were different between the H and the D components,as well as between the long and short periods.展开更多
A graph G possesses Hamiltonian s-properties when G is Hamilton-connected if s=1,Hamiltonian if s=0,and traceable if s=-1.Let S_A(G)=λ_n(G)-λ_1(G)and S_L(G)=μ_n(G)-μ_2(G)be the spread and the Laplacian spread of G...A graph G possesses Hamiltonian s-properties when G is Hamilton-connected if s=1,Hamiltonian if s=0,and traceable if s=-1.Let S_A(G)=λ_n(G)-λ_1(G)and S_L(G)=μ_n(G)-μ_2(G)be the spread and the Laplacian spread of G,respectively,whereλ_n(G)andλ_1(G)are the largest and smallest eigenvalues of G,andμ_n(G)andμ_2(G)are the largest and second smallest Laplacian eigenvalues of G,respectively.In this paper,we shall present two sufficient conditions involving S_A(G)and S_L(G)for a k-connected graph to possess Hamiltonian s-properties,respectively.We also derive a sufficient condition on the Laplacian eigenratio■for a k-connected graph to possess Hamiltonian s-properties.展开更多
Bending deformation behaviors of solution treated(ST),natural aged(NA)and T6tempered6063aluminum alloy sheetswere studied by three-point bending tests.The changes of bending force,interior angle,bending radius and she...Bending deformation behaviors of solution treated(ST),natural aged(NA)and T6tempered6063aluminum alloy sheetswere studied by three-point bending tests.The changes of bending force,interior angle,bending radius and sheet thickness in thefillet region were analyzed by experimental measurements and numerical simulations.The results showed that the bendingcharacteristics were strongly dependent on the heat treatment conditions.The T6alloy sheets were bent more sharply and localplastic deformation occurred severely in the fillet region.However,the ST and NA alloy sheets exhibited relatively uniform bendingdeformation and large bending radius.The bending force of T6alloy was the highest,followed by the NA alloy and that of the STalloy was minimum.After unloading,as compared with the ST and NA alloys,the springback of T6alloys was markedly larger.Theaging time showed a positive sensitivity on the springback and non-uniform bending deformability.The bending characteristics areattributed to the combined effects of yield strength,yield ratio and coefficient of neutral layer.展开更多
This paper presents the application of bifurcation method on the steady state three-phase load-flow Jacobian method to study the voltage stability of unbalanced distribution systems. The eigenvalue analysis is used to...This paper presents the application of bifurcation method on the steady state three-phase load-flow Jacobian method to study the voltage stability of unbalanced distribution systems. The eigenvalue analysis is used to study distribution system behavior under different operating conditions. Two-bus connected by asymmetrical line is used as the study system. The effects of both unbalance and extreme loading conditions are investigated. Also, the impact of distributed energy resources is studied. Different case studies and loading scenarios are presented to trace the eigenvalues of the Jacobian matrix. The results exhibit the existence of a new bifurcation point which may not be related to the voltage stability.展开更多
In this paper, we work on compact quasi-Einstein metrics and prove several gap results. In the first part, we get a gap estimate for the first nonzero eigenvalue of the weighted Laplacian, by establishing a comparison...In this paper, we work on compact quasi-Einstein metrics and prove several gap results. In the first part, we get a gap estimate for the first nonzero eigenvalue of the weighted Laplacian, by establishing a comparison theorem for the weighted heat kernel. In the second part, we establish two gap results for the Ricci curvature and the scalar curvature, based on which some rigid properties can be derived.展开更多
This paper establishes a new Laplacian comparison theorem which is specially useful tothe mathelds of nonpositive curvature. It leads naturally to the corresponding heat kernelcomparison and eigenvalue comparison theo...This paper establishes a new Laplacian comparison theorem which is specially useful tothe mathelds of nonpositive curvature. It leads naturally to the corresponding heat kernelcomparison and eigenvalue comparison theorems. Furthermore, a lower estimate of L2-spectrumof an n-dimensional non-compact complete Cartan-Hadamard manifold is given by (n-1)k/4,provided its mRicci curvature -(n -1)k (k= const. 0).展开更多
Cheng-type inequality, Cheeger-type inequality and Faber-Krahn-type inequality are generalized to Finsler manifolds. For a compact Finsler manifold with the weighted Ricci curvature bounded from below by a negative co...Cheng-type inequality, Cheeger-type inequality and Faber-Krahn-type inequality are generalized to Finsler manifolds. For a compact Finsler manifold with the weighted Ricci curvature bounded from below by a negative constant, Li-Yau's estimation of the first eigenvalue is also given.展开更多
Giant earthquakes generate rich signals that can be used to explore the characteristics of the hierarchical structure of the Earth’s interior associated with the eigenfrequencies of the Earth.We employ the spectral e...Giant earthquakes generate rich signals that can be used to explore the characteristics of the hierarchical structure of the Earth’s interior associated with the eigenfrequencies of the Earth.We employ the spectral element method,incorporated with large-scale parallel computing technology,to investigate the characteristics of global seismic wave propagation excited by the2011 Mw9.0 Tohoku earthquake.The transversely isotropic PREM model is employed as a prototype of our numerical global Earth model.Topographic data and the effect of the oceans are taken into consideration.Wave propagation processes are simulated by solving three-dimensional elastic wave governing equations with the seismic moment tensor obtained from the Global Centroid Moment Tensor Catalog.Three-dimensional visualization of our computing results displays the nature of the global seismic wave propagation.Comparative analysis of our calculations with observations obtained from the Incorporated Research Institutions for Seismology demonstrates the reliability and feasibility of our numerical results.We compare synthetic seismograms with incorporated and unincorporated ocean models.First results show that the oceans have obvious effects on the characteristics of seismic wave propagation.The peak displacement and peak velocity of P waves become relatively small under the effect of the ocean.However,the effect of the ocean on S-waves is complex.The displacement and velocity of S waves decrease rapidly over time using an unincorporated ocean model.Therefore,the effects of the ocean should be incorporated when undertaking quantitative earthquake hazard assessments on coastal areas.In addition,we undertake comparative analysis on the characteristics of the Earth’s oscillation excited by the 2004 Sumatra-Andaman,2008 Wenchuan,and 2011Tohoku earthquakes that incorporate the effect of the Earth’s gravitational potential.A comparison of the amplitude spectra of the numerical records indicates that energy released by the three big earthquakes is different.Our comparative analysis realizes that the computing results can accurately reproduce some eigenfrequencies of the Earth,such as toroidal modes 0T2 to 0T13and spheroidal modes 0S7 to 0S31.These results demonstrate that numerical simulations can be successfully used to investigate the Earth’s oscillations.We propose that numerical simulations can be used as one of the major tools to further reveal how the Earth’s lateral heterogeneities affect the Earth’s oscillations.展开更多
We are concerned with the maximization of tr(V T AV)/tr(V T BV)+tr(V T CV) over the Stiefel manifold {V ∈ R m×l | V T V = Il} (l 〈 m), where B is a given symmetric and positive definite matrix, A and...We are concerned with the maximization of tr(V T AV)/tr(V T BV)+tr(V T CV) over the Stiefel manifold {V ∈ R m×l | V T V = Il} (l 〈 m), where B is a given symmetric and positive definite matrix, A and C are symmetric matrices, and tr(. ) is the trace of a square matrix. This is a subspace version of the maximization problem studied in Zhang (2013), which arises from real-world applications in, for example, the downlink of a multi-user MIMO system and the sparse Fisher discriminant analysis in pattern recognition. We establish necessary conditions for both the local and global maximizers and connect the problem with a nonlinear extreme eigenvalue problem. The necessary condition for the global maximizers offers deep insights into the problem, on the one hand, and, on the other hand, naturally leads to a self-consistent-field (SCF) iteration to be presented and analyzed in detail in Part II of this paper.展开更多
文摘AIM To investigate the prognostic value of preoperative fbri-nogen concentration (FIB) and D-dimer-fibrinogen ratio (DFR) in gastrointestinal stromal tumors (GISTs).METHODS The purpose of this study was to retrospectively ana-lyze 170 patients with GISTs who were admitted to our hospital from January 2010 to December 2015. The op-timal cutoff values of related parameters were estimated by receiver operating characteristic (ROC) curve analysis. The recurrence free survival (RFS) rate was evaluated using Kaplan-Meier curves. Univariate analysis and multivariate Cox regression models were used to analyze the prognostic factors of GISTs. The relationship between the FIB, D-dimer, DFR, platelet count (PLT), and the clinicopathological features of GISTs was described by the chi-square test or nonparametric rank sum test (Mann-Whitney test).RESULTS In ROC analysis, the optimal cutoff values of FIB, D-dimer, DFR, and PLT were 3.24 g/L, 1.24 mg/L, 0.354, and 197.5 (× 109/L), respectively. Univariate analysis and the Kaplan-Meier survival curve showed that FIB, D-dimer, DFR, PLT,National Institutes of Health (NIH) risk category, tumor size, tumor location, and mitotic index were signifcantly relevant to the 3-year and 5-year survival rate of patients ( P 〈 0.05). Cox multivariate regression analysis illustrated that FIB (RR: 0.108, 95%CI: 0.031-0.373), DFR (RR: 0.319, 95%CI: 0.131-0.777), and NIH risk category ( RR: 0.166, 95%CI: 0.047-0.589) were independent prognostic factors of the RFS rate ( P 〈 0. 05). Moreover, FIB, D-dimer, DFR, and PLT were correlated with the clinical features of GISTs.CONCLUSIONFIB, D-dimer, DFR, and PLT are all related to the prognosis of GISTs. Moreover, FIB and DFR may be independent risk factors for predicting the prognosis of resectable GISTs.
基金funded by the routine task entitled“The Routine Recognition and Tracking of HVDC's Interference in Geomagnetic Observation”of the Technical Management Group of Electromagnetic Discipline,CEA
文摘In this paper,the Gaoyou-Baoying M_S4.9 earthquake was analyzed by the geomagnetic harmonic wave amplitude ratios method. The earthquake was an isolated seismic event,before and after which there were no other earthquakes occurred in this region. The dense distribution of geomagnetic observataries provided an advantage condition for the analysis of characteristics of the geomagnetic harmonic amplitude ratios. The analysis results verify the former knowledge of anomaly characteristics of the geomagnetic harmonic amplitude ratio,that is,the anomalous characteristics of the earthquake mostly appeared during the decline-turning-recovery rising process. The results also show that the change of the anomalies was asynchronous at the observatories close to the epicenter, namely, the anomalous characteristics were different between the H and the D components,as well as between the long and short periods.
基金Supported by NSFC(Nos.12171089,12271235)NSF of Fujian Province(No.2021J02048)。
文摘A graph G possesses Hamiltonian s-properties when G is Hamilton-connected if s=1,Hamiltonian if s=0,and traceable if s=-1.Let S_A(G)=λ_n(G)-λ_1(G)and S_L(G)=μ_n(G)-μ_2(G)be the spread and the Laplacian spread of G,respectively,whereλ_n(G)andλ_1(G)are the largest and smallest eigenvalues of G,andμ_n(G)andμ_2(G)are the largest and second smallest Laplacian eigenvalues of G,respectively.In this paper,we shall present two sufficient conditions involving S_A(G)and S_L(G)for a k-connected graph to possess Hamiltonian s-properties,respectively.We also derive a sufficient condition on the Laplacian eigenratio■for a k-connected graph to possess Hamiltonian s-properties.
基金Projects(U1664252,51605234)supported by the National Natural Science Foundation of ChinaProject(2016YFB0101700)supported by the National Key Research and Development Program of ChinaProject(31665004)supported by the Open Fund of State Key Laboratory of Advanced Design and Manufacture for Vehicle Body
文摘Bending deformation behaviors of solution treated(ST),natural aged(NA)and T6tempered6063aluminum alloy sheetswere studied by three-point bending tests.The changes of bending force,interior angle,bending radius and sheet thickness in thefillet region were analyzed by experimental measurements and numerical simulations.The results showed that the bendingcharacteristics were strongly dependent on the heat treatment conditions.The T6alloy sheets were bent more sharply and localplastic deformation occurred severely in the fillet region.However,the ST and NA alloy sheets exhibited relatively uniform bendingdeformation and large bending radius.The bending force of T6alloy was the highest,followed by the NA alloy and that of the STalloy was minimum.After unloading,as compared with the ST and NA alloys,the springback of T6alloys was markedly larger.Theaging time showed a positive sensitivity on the springback and non-uniform bending deformability.The bending characteristics areattributed to the combined effects of yield strength,yield ratio and coefficient of neutral layer.
文摘This paper presents the application of bifurcation method on the steady state three-phase load-flow Jacobian method to study the voltage stability of unbalanced distribution systems. The eigenvalue analysis is used to study distribution system behavior under different operating conditions. Two-bus connected by asymmetrical line is used as the study system. The effects of both unbalance and extreme loading conditions are investigated. Also, the impact of distributed energy resources is studied. Different case studies and loading scenarios are presented to trace the eigenvalues of the Jacobian matrix. The results exhibit the existence of a new bifurcation point which may not be related to the voltage stability.
基金supported by Natural Science Foundation of Jiangsu Province (Grant No. BK20141235)
文摘In this paper, we work on compact quasi-Einstein metrics and prove several gap results. In the first part, we get a gap estimate for the first nonzero eigenvalue of the weighted Laplacian, by establishing a comparison theorem for the weighted heat kernel. In the second part, we establish two gap results for the Ricci curvature and the scalar curvature, based on which some rigid properties can be derived.
文摘This paper establishes a new Laplacian comparison theorem which is specially useful tothe mathelds of nonpositive curvature. It leads naturally to the corresponding heat kernelcomparison and eigenvalue comparison theorems. Furthermore, a lower estimate of L2-spectrumof an n-dimensional non-compact complete Cartan-Hadamard manifold is given by (n-1)k/4,provided its mRicci curvature -(n -1)k (k= const. 0).
基金supported by the National Natural Science Foundation of China(Nos.11471246,11171253)the Natural Science Foundation of the Anhui Higher Education Institutions(No.KJ2014A257)
文摘Cheng-type inequality, Cheeger-type inequality and Faber-Krahn-type inequality are generalized to Finsler manifolds. For a compact Finsler manifold with the weighted Ricci curvature bounded from below by a negative constant, Li-Yau's estimation of the first eigenvalue is also given.
基金supported by the National High Technology Research and Development Program (Grant No. 2010AA012402)the Ministry of Land and Resources Industry Fund (Grant No. SinoProbe-07)+1 种基金China Earthquake Administration Earthquake Industry-Scientific Research Fund (Grant No. 200808077)the Open Foundation of State Key Laboratory of Earthquake Dynamics.
文摘Giant earthquakes generate rich signals that can be used to explore the characteristics of the hierarchical structure of the Earth’s interior associated with the eigenfrequencies of the Earth.We employ the spectral element method,incorporated with large-scale parallel computing technology,to investigate the characteristics of global seismic wave propagation excited by the2011 Mw9.0 Tohoku earthquake.The transversely isotropic PREM model is employed as a prototype of our numerical global Earth model.Topographic data and the effect of the oceans are taken into consideration.Wave propagation processes are simulated by solving three-dimensional elastic wave governing equations with the seismic moment tensor obtained from the Global Centroid Moment Tensor Catalog.Three-dimensional visualization of our computing results displays the nature of the global seismic wave propagation.Comparative analysis of our calculations with observations obtained from the Incorporated Research Institutions for Seismology demonstrates the reliability and feasibility of our numerical results.We compare synthetic seismograms with incorporated and unincorporated ocean models.First results show that the oceans have obvious effects on the characteristics of seismic wave propagation.The peak displacement and peak velocity of P waves become relatively small under the effect of the ocean.However,the effect of the ocean on S-waves is complex.The displacement and velocity of S waves decrease rapidly over time using an unincorporated ocean model.Therefore,the effects of the ocean should be incorporated when undertaking quantitative earthquake hazard assessments on coastal areas.In addition,we undertake comparative analysis on the characteristics of the Earth’s oscillation excited by the 2004 Sumatra-Andaman,2008 Wenchuan,and 2011Tohoku earthquakes that incorporate the effect of the Earth’s gravitational potential.A comparison of the amplitude spectra of the numerical records indicates that energy released by the three big earthquakes is different.Our comparative analysis realizes that the computing results can accurately reproduce some eigenfrequencies of the Earth,such as toroidal modes 0T2 to 0T13and spheroidal modes 0S7 to 0S31.These results demonstrate that numerical simulations can be successfully used to investigate the Earth’s oscillations.We propose that numerical simulations can be used as one of the major tools to further reveal how the Earth’s lateral heterogeneities affect the Earth’s oscillations.
基金supported by National Natural Science Foundation of China(Grant Nos.11101257 and 11371102)the Basic Academic Discipline Program+3 种基金the 11th Five Year Plan of 211 Project for Shanghai University of Finance and Economicsa visiting scholar at the Department of Mathematics,University of Texas at Arlington from February 2013 toJanuary 2014supported by National Science Foundation of USA(Grant Nos.1115834and 1317330)a Research Gift Grant from Intel Corporation
文摘We are concerned with the maximization of tr(V T AV)/tr(V T BV)+tr(V T CV) over the Stiefel manifold {V ∈ R m×l | V T V = Il} (l 〈 m), where B is a given symmetric and positive definite matrix, A and C are symmetric matrices, and tr(. ) is the trace of a square matrix. This is a subspace version of the maximization problem studied in Zhang (2013), which arises from real-world applications in, for example, the downlink of a multi-user MIMO system and the sparse Fisher discriminant analysis in pattern recognition. We establish necessary conditions for both the local and global maximizers and connect the problem with a nonlinear extreme eigenvalue problem. The necessary condition for the global maximizers offers deep insights into the problem, on the one hand, and, on the other hand, naturally leads to a self-consistent-field (SCF) iteration to be presented and analyzed in detail in Part II of this paper.