基于临界距离法原理,提出馈线临界比距的概念,针对几种环网配电网络,讨论了馈线临界比距的计算方法,根据馈线临界比距的数值可分析各出线故障对公共连接点 (point of common coupling,PCC)电压暂降的影响程度以及快速确定导致PCC点严重...基于临界距离法原理,提出馈线临界比距的概念,针对几种环网配电网络,讨论了馈线临界比距的计算方法,根据馈线临界比距的数值可分析各出线故障对公共连接点 (point of common coupling,PCC)电压暂降的影响程度以及快速确定导致PCC点严重电压暂降的输电线路。与临界距离法相比,临界比距法避免了临界距离超出线路长度的情况,在确定电压暂降暴露域时物理概念更加清晰。估算结果与实际测量结果的比较证明了该方法的有效性。展开更多
In order to obtain stable interval Q factor, by analyzing the spectrum of monitoring wavelet and down-going wavelet of zero-offset VSP data and referring the spectrum expression of Ricker wavelet, we propose a new exp...In order to obtain stable interval Q factor, by analyzing the spectrum of monitoring wavelet and down-going wavelet of zero-offset VSP data and referring the spectrum expression of Ricker wavelet, we propose a new expression of source wavelet spectrum. Basing on the new expression, we present improved amplitude spectral fitting and spectral ratio methods for interval Q inversion based on zero-offset VSP data, and the sequence for processing the zero-offset VSP data. Subsequently, we apply the proposed methods to real zero-offset VSP data, and carry out prestack inverse Q filtering to zero-offset VSP data and surface seismic data for amplitude compensation with the estimated Q value.展开更多
To discover new lead compounds for M1 agonists. Ten typical M1 agonists were superimposed to build a M1 agonists 3D-pharmacophore model using distance-comparisons （DISCO） method without the previous knowledge of the...To discover new lead compounds for M1 agonists. Ten typical M1 agonists were superimposed to build a M1 agonists 3D-pharmacophore model using distance-comparisons （DISCO） method without the previous knowledge of the three-dimensional structure of M1 receptor. Virtual screening strategy was used to analyze the Available Chemicals Directory-Screening Compounds （ACD-SC） to identify possible new hits. Twenty-two compounds which fit the pharmacophore model well and are not similar with known M1 agonists were purchased in order to evaluate their M1 receptor agonist activity. One of them shows M1 receptor agonist activity with EC50 of 4.90 μmol/L and maximum response. Multiple of 10.0 which shows it worthy of further study as a new lead compound for M1 agonists.展开更多
文摘基于临界距离法原理,提出馈线临界比距的概念,针对几种环网配电网络,讨论了馈线临界比距的计算方法,根据馈线临界比距的数值可分析各出线故障对公共连接点 (point of common coupling,PCC)电压暂降的影响程度以及快速确定导致PCC点严重电压暂降的输电线路。与临界距离法相比,临界比距法避免了临界距离超出线路长度的情况,在确定电压暂降暴露域时物理概念更加清晰。估算结果与实际测量结果的比较证明了该方法的有效性。
基金sponsored by the National Nature Science Foundation of China(Nos.41174114 and 41274128)
文摘In order to obtain stable interval Q factor, by analyzing the spectrum of monitoring wavelet and down-going wavelet of zero-offset VSP data and referring the spectrum expression of Ricker wavelet, we propose a new expression of source wavelet spectrum. Basing on the new expression, we present improved amplitude spectral fitting and spectral ratio methods for interval Q inversion based on zero-offset VSP data, and the sequence for processing the zero-offset VSP data. Subsequently, we apply the proposed methods to real zero-offset VSP data, and carry out prestack inverse Q filtering to zero-offset VSP data and surface seismic data for amplitude compensation with the estimated Q value.
基金National Natural Science Foundation of China (Grant No. 30271538)985 program,Ministry of Education of China
文摘To discover new lead compounds for M1 agonists. Ten typical M1 agonists were superimposed to build a M1 agonists 3D-pharmacophore model using distance-comparisons （DISCO） method without the previous knowledge of the three-dimensional structure of M1 receptor. Virtual screening strategy was used to analyze the Available Chemicals Directory-Screening Compounds （ACD-SC） to identify possible new hits. Twenty-two compounds which fit the pharmacophore model well and are not similar with known M1 agonists were purchased in order to evaluate their M1 receptor agonist activity. One of them shows M1 receptor agonist activity with EC50 of 4.90 μmol/L and maximum response. Multiple of 10.0 which shows it worthy of further study as a new lead compound for M1 agonists.
