毛是哺乳动物所特有的组织,曾有报道,随个体年龄增长或某些疾病及药物会引起哺乳动物毛表面的毛小皮鳞片发生一系列的变化。(fujita et al.,1971)。所以毛形的变化可用于检测或筛选某些药物的疗效,其明显优点是取材对机体无损伤,且简单...毛是哺乳动物所特有的组织,曾有报道,随个体年龄增长或某些疾病及药物会引起哺乳动物毛表面的毛小皮鳞片发生一系列的变化。(fujita et al.,1971)。所以毛形的变化可用于检测或筛选某些药物的疗效,其明显优点是取材对机体无损伤,且简单易行,又便于重复实验。 本实验用Wistar种雄性大鼠,饲以中药复方人参茎叶皂甙(简称8401,由沈阳中医研究所药理室处方设计,本溪市中药制药厂制备),观察其对毛形变化的影响,并与饲以人参根皂甙大鼠毛对比。展开更多
Recently, the development of endoscopic procedures has increased the availability of minimally invasive treatments; however, there have been few case reports of duodenal hemangioma treated by endoscopic mucosal resect...Recently, the development of endoscopic procedures has increased the availability of minimally invasive treatments; however, there have been few case reports of duodenal hemangioma treated by endoscopic mucosal resection. The present report describes a case of duodenal hemangioma that showed various endoscopic changes over time and was treated by endoscopic mucosal resection. An 80-year-old woman presented with tarry stools and a loss of appetite. An examination of her blood revealed severe anemia, and her hemoglobin level was 4.2 g/dL. An emergency upper gastrointestinal endoscopy was performed. A red, protrusive, semipedunculated tumor (approximately 20 mm in diameter) with spontaneous bleeding on its surface was found in the superior duodenal angle. Given the semipedunculated appearance of the tumor, it was suspected to be an epithelial tumor with a differential diagnosis of hyperplastic polyp. The biopsy results suggested a telangiectatic hemangioma. Because this lesion was considered to be responsible for her anemia, endoscopic mucosal resection was performed for diagnostic and treatment purposes after informed consent was obtained. A histopathological examination of the resected specimen revealed dilated and proliferated capillary lumens of various sizes, which confirmed the final diagnosis of duodenal hemangioma. Neither anemia nor tumor recurrence has been observed since the endoscopic mucosal resection (approximately 1 year). Duodenal hemangiomas can be treated endoscopically provided that sufficient consideration is given to all of the possible treatment strategies. Interestingly, duodenal hemangiomas show morphological changes that are influenced by various factors, such as mechanical stimuli.展开更多
文摘毛是哺乳动物所特有的组织,曾有报道,随个体年龄增长或某些疾病及药物会引起哺乳动物毛表面的毛小皮鳞片发生一系列的变化。(fujita et al.,1971)。所以毛形的变化可用于检测或筛选某些药物的疗效,其明显优点是取材对机体无损伤,且简单易行,又便于重复实验。 本实验用Wistar种雄性大鼠,饲以中药复方人参茎叶皂甙(简称8401,由沈阳中医研究所药理室处方设计,本溪市中药制药厂制备),观察其对毛形变化的影响,并与饲以人参根皂甙大鼠毛对比。
文摘Recently, the development of endoscopic procedures has increased the availability of minimally invasive treatments; however, there have been few case reports of duodenal hemangioma treated by endoscopic mucosal resection. The present report describes a case of duodenal hemangioma that showed various endoscopic changes over time and was treated by endoscopic mucosal resection. An 80-year-old woman presented with tarry stools and a loss of appetite. An examination of her blood revealed severe anemia, and her hemoglobin level was 4.2 g/dL. An emergency upper gastrointestinal endoscopy was performed. A red, protrusive, semipedunculated tumor (approximately 20 mm in diameter) with spontaneous bleeding on its surface was found in the superior duodenal angle. Given the semipedunculated appearance of the tumor, it was suspected to be an epithelial tumor with a differential diagnosis of hyperplastic polyp. The biopsy results suggested a telangiectatic hemangioma. Because this lesion was considered to be responsible for her anemia, endoscopic mucosal resection was performed for diagnostic and treatment purposes after informed consent was obtained. A histopathological examination of the resected specimen revealed dilated and proliferated capillary lumens of various sizes, which confirmed the final diagnosis of duodenal hemangioma. Neither anemia nor tumor recurrence has been observed since the endoscopic mucosal resection (approximately 1 year). Duodenal hemangiomas can be treated endoscopically provided that sufficient consideration is given to all of the possible treatment strategies. Interestingly, duodenal hemangiomas show morphological changes that are influenced by various factors, such as mechanical stimuli.
