Objective: The aim of the study was to evaluate the clinical significance of multiple tumor markers (CEA, AFP, CA72-4 and CA19-9) in patients with gastrocolic tumors by receiver operating characteristic (ROC) curve an...Objective: The aim of the study was to evaluate the clinical significance of multiple tumor markers (CEA, AFP, CA72-4 and CA19-9) in patients with gastrocolic tumors by receiver operating characteristic (ROC) curve and stepwise logistic regression (LR) analysis. Methods: The serum concentrations of CEA, AFP, CA72-4 and CA19-9 were measured with electrochemiluminescence immunoassay in 126 patients with gastrocolic tumors, 137 patients with benign gastrocolic disorders and 109 healthy controls. The area under the ROC curve (AUC) of CEA, AFP, CA72-4 and CA19-9 and stepwise LR results were compared by sensitivity, specificity, Youden's index and positive likelihood ratio/negative likelihood ratio. Results: The levels of four tested tumor markers in patients with gastrocolic tumors were significantly higher than those in benign gastrocolic group and normal controls. In the benign gastrocolic group, the AUC from stepwise logistic regression was larger than the AUC of four tumor markers respectively. Sensitivity, Youden's index and positive likelihood ratio/negative likelihood ratio were the highest in the combination assay of CA72-4, CEA, and CA19-9, as compared with one of the tumor markers alone. Conclusion: The use of ROC established by LR analysis model improved the diagnostic accuracy of gastrocolic tumors. For the screening of gastrocolic tumors, the AUC value of the combination probability index (sensitivity and specificity) was significantly higher than the values of the different tumour markers.展开更多
Objective:Autoethnography combines personal experiences with cultural analysis,emerging as a response to the limitations of traditional ethnography.This review aimed to explore,describe,and delineate the utilization o...Objective:Autoethnography combines personal experiences with cultural analysis,emerging as a response to the limitations of traditional ethnography.This review aimed to explore,describe,and delineate the utilization of autoethnography by nurses published in peer-reviewed journals.Methods:A scoping review was conducted according to the Arksey and O’Malley framework.On October 12,2023,autoethnographic studies in nursing were identified through searches of CINAHL,PubMed,PsycINFO,and Scopus.Peer-reviewed articles published in English language were retrieved.We applied no date restriction.Data were extracted on nursing,epiphany,results,style of writing,implications for nursing,and ethical considerations.Results:Twenty-six articles met the inclusion criteria.Mental health nursing,covered by nine articles,elucidated experiences of stigma,ethical dilemmas,and professional identity.Nursing education,represented by seven articles,highlighted identity struggles,systemic biases,and evolving pedagogies.Palliative care,addressed by three articles,provided insights into communication challenges and emotional complexities in end-of-life care.The remaining articles explored rehabilitation,cultural competence,and chronic pain management.A conceptual framework integrating ontological,epistemological,ethical,and practical dimensions was developed,emphasizing the interplay between personal and professional roles.Conclusions:This review underscores autoethnography’s value in uncovering the cultural and ethical dimensions of nursing.This framework advocates for a reflective,culturally attuned approach to healthcare,fostering transformative changes in nursing.Further research should explore underrepresented nursing specialties to harness autoethnography’s potential fully.展开更多
In the Chinese higher education sector, Business English, a newly emerging discipline, has attracted great attention, and since it was approved officially in 2007, about 400 universities and colleges have offered this...In the Chinese higher education sector, Business English, a newly emerging discipline, has attracted great attention, and since it was approved officially in 2007, about 400 universities and colleges have offered this degree course to students. Among in-service Business English teachers, some of them have transferred from teaching English for General Purposes. Business English teachers face many changes and challenges to their professional identity, yet few scholars have looked into the identity construction of these teachers. Using critical narrative as a method, this paper closely examines the identity construction experiences of the first author and two other Business English teachers. It is found that the participants, including the first author himself, have endured identity negotiations and various challenges in turning from a teacher of English for General Purposes to a teacher of Business English. These teachers' experiences and their perception of identity construction and professional development throw light on the changing pedagogy and practice of Business English in Chinese universities.展开更多
Neoliberalism has emerged as a keyword that captures some core features of global economic and educational reforms in recent years. This paper reports a linguistic ethnographic study of how a Chinese language teacher ...Neoliberalism has emerged as a keyword that captures some core features of global economic and educational reforms in recent years. This paper reports a linguistic ethnographic study of how a Chinese language teacher was engaged with neoliberal discourses on language education in and out of the classroom in a suburban public middle school in China, with an attempt to illuminate the complexity of language education in a neoliberal context. The analysis shows three general identity positions-as an opponent, a conformist, and a pragmatist-across the identification trajectory of the focal language teacher through the fieldwork period, in relation to neoliberal exam-oriented education and her various ways of engaging with exam discourses in her language classrooms. This inquiry argues for the perspective of unpredictability and complexity as an alternative that goes beyond the current "deterministic neoliberalism" in understanding the dynamics of neoliberalization in language education, language teaching, and teacher identity formation.展开更多
The German aesthetic discourse of modernity is the self-manifestation of German historical development from early modern times. German cultural ecology, comprising German natural, historical, social and intellectual f...The German aesthetic discourse of modernity is the self-manifestation of German historical development from early modern times. German cultural ecology, comprising German natural, historical, social and intellectual factors, has determined the historical fate of the German aesthetic discourse of modernity and also, realistically, its essential characteristics. The Protestant spirit is the soul of the national consciousness, intellectual concepts, cultural understanding and life experience of the Germans, who take culture as the foundation of their nation. German civic cultural ecology--the social structure, way of life and cultural institutions that originated and developed in civil society--to a great extent determined the form of the German aesthetic discourse of modernity. The three salient features of German enlightenment thought, i.e., the establishment of perception and the independence of beauty, the adjustment of rationalism and the birth of value rationality, and the establishment of the public character of art, are the constituent elements of German cultural ecology.展开更多
基金Supported by grants from Major Project Grant of Department of Education of the Sichuan Province (No. 09ZA045)the Public Health Project Grant of Sichuan Province (No. 100258)the Affiliated Hospital of Luzhou Medical College (No. 201143)
文摘Objective: The aim of the study was to evaluate the clinical significance of multiple tumor markers (CEA, AFP, CA72-4 and CA19-9) in patients with gastrocolic tumors by receiver operating characteristic (ROC) curve and stepwise logistic regression (LR) analysis. Methods: The serum concentrations of CEA, AFP, CA72-4 and CA19-9 were measured with electrochemiluminescence immunoassay in 126 patients with gastrocolic tumors, 137 patients with benign gastrocolic disorders and 109 healthy controls. The area under the ROC curve (AUC) of CEA, AFP, CA72-4 and CA19-9 and stepwise LR results were compared by sensitivity, specificity, Youden's index and positive likelihood ratio/negative likelihood ratio. Results: The levels of four tested tumor markers in patients with gastrocolic tumors were significantly higher than those in benign gastrocolic group and normal controls. In the benign gastrocolic group, the AUC from stepwise logistic regression was larger than the AUC of four tumor markers respectively. Sensitivity, Youden's index and positive likelihood ratio/negative likelihood ratio were the highest in the combination assay of CA72-4, CEA, and CA19-9, as compared with one of the tumor markers alone. Conclusion: The use of ROC established by LR analysis model improved the diagnostic accuracy of gastrocolic tumors. For the screening of gastrocolic tumors, the AUC value of the combination probability index (sensitivity and specificity) was significantly higher than the values of the different tumour markers.
文摘Objective:Autoethnography combines personal experiences with cultural analysis,emerging as a response to the limitations of traditional ethnography.This review aimed to explore,describe,and delineate the utilization of autoethnography by nurses published in peer-reviewed journals.Methods:A scoping review was conducted according to the Arksey and O’Malley framework.On October 12,2023,autoethnographic studies in nursing were identified through searches of CINAHL,PubMed,PsycINFO,and Scopus.Peer-reviewed articles published in English language were retrieved.We applied no date restriction.Data were extracted on nursing,epiphany,results,style of writing,implications for nursing,and ethical considerations.Results:Twenty-six articles met the inclusion criteria.Mental health nursing,covered by nine articles,elucidated experiences of stigma,ethical dilemmas,and professional identity.Nursing education,represented by seven articles,highlighted identity struggles,systemic biases,and evolving pedagogies.Palliative care,addressed by three articles,provided insights into communication challenges and emotional complexities in end-of-life care.The remaining articles explored rehabilitation,cultural competence,and chronic pain management.A conceptual framework integrating ontological,epistemological,ethical,and practical dimensions was developed,emphasizing the interplay between personal and professional roles.Conclusions:This review underscores autoethnography’s value in uncovering the cultural and ethical dimensions of nursing.This framework advocates for a reflective,culturally attuned approach to healthcare,fostering transformative changes in nursing.Further research should explore underrepresented nursing specialties to harness autoethnography’s potential fully.
基金supported by Shanghai University of Finance and Economics [Grant No.2019110115]the National Research Fund for Social Sciences [Grant No.16BYY178]
文摘In the Chinese higher education sector, Business English, a newly emerging discipline, has attracted great attention, and since it was approved officially in 2007, about 400 universities and colleges have offered this degree course to students. Among in-service Business English teachers, some of them have transferred from teaching English for General Purposes. Business English teachers face many changes and challenges to their professional identity, yet few scholars have looked into the identity construction of these teachers. Using critical narrative as a method, this paper closely examines the identity construction experiences of the first author and two other Business English teachers. It is found that the participants, including the first author himself, have endured identity negotiations and various challenges in turning from a teacher of English for General Purposes to a teacher of Business English. These teachers' experiences and their perception of identity construction and professional development throw light on the changing pedagogy and practice of Business English in Chinese universities.
基金the support from the Key Research Project of Philosophy and Social Science of the Ministry of Education of China (MOE, Project No.: 15JZD048)the Chinese MOE Research Project of Humanities and Social Science (Project No.: 16JJD740006) conducted by the Center for Linguistics and Applied Linguistics, Guangdong University of Foreign Studiesthe Research Project Guangdong Planning Office of Philosophy and Social Science (Project No.: GD18WXZ18)
文摘Neoliberalism has emerged as a keyword that captures some core features of global economic and educational reforms in recent years. This paper reports a linguistic ethnographic study of how a Chinese language teacher was engaged with neoliberal discourses on language education in and out of the classroom in a suburban public middle school in China, with an attempt to illuminate the complexity of language education in a neoliberal context. The analysis shows three general identity positions-as an opponent, a conformist, and a pragmatist-across the identification trajectory of the focal language teacher through the fieldwork period, in relation to neoliberal exam-oriented education and her various ways of engaging with exam discourses in her language classrooms. This inquiry argues for the perspective of unpredictability and complexity as an alternative that goes beyond the current "deterministic neoliberalism" in understanding the dynamics of neoliberalization in language education, language teaching, and teacher identity formation.
基金the National Social Science Fund Project "Research on the Artistic Aesthetic Discourse of German Cultural Enlightenment and Modernity"(No.:10BZW022)
文摘The German aesthetic discourse of modernity is the self-manifestation of German historical development from early modern times. German cultural ecology, comprising German natural, historical, social and intellectual factors, has determined the historical fate of the German aesthetic discourse of modernity and also, realistically, its essential characteristics. The Protestant spirit is the soul of the national consciousness, intellectual concepts, cultural understanding and life experience of the Germans, who take culture as the foundation of their nation. German civic cultural ecology--the social structure, way of life and cultural institutions that originated and developed in civil society--to a great extent determined the form of the German aesthetic discourse of modernity. The three salient features of German enlightenment thought, i.e., the establishment of perception and the independence of beauty, the adjustment of rationalism and the birth of value rationality, and the establishment of the public character of art, are the constituent elements of German cultural ecology.
