本文以角叉菜胶（Car）25mg·kg<sup>-1</sup>诱导大鼠气囊滑膜炎模型为研究对象,观察了三七叶皂甙（PNGL）对Car诱导的气囊灌洗液中白细胞数及蛋白含量的影响,与此同时,还进一步观察了PNGL对灌洗液中PGE<sub>2&l...本文以角叉菜胶（Car）25mg·kg<sup>-1</sup>诱导大鼠气囊滑膜炎模型为研究对象,观察了三七叶皂甙（PNGL）对Car诱导的气囊灌洗液中白细胞数及蛋白含量的影响,与此同时,还进一步观察了PNGL对灌洗液中PGE<sub>2</sub>含量及PLA<sub>2</sub>活性的影响。结果发现,Car致炎后气囊灌洗液中PLA<sub>2</sub>活性明显升高,于12h达峰值(248.5±41.8 vs 38.4±9.2U·ml<sup>-1</sup>,P【0.01);PGE<sub>2</sub>含量呈类似变化(1619±391 vs 397±41pg·mg<sup>-1</sup>,P【0.01);灌洗液中白细胞数及蛋白含量也显著升高(P均【0.展开更多
A 67-years-old male presented with periumbilical abdominal pain, fever and jaundice. His anaerobic blood culture was positive for clostridium perfringens. Computed tomogram scan of the abdomen and abdominal ultrasound...A 67-years-old male presented with periumbilical abdominal pain, fever and jaundice. His anaerobic blood culture was positive for clostridium perfringens. Computed tomogram scan of the abdomen and abdominal ultrasound showed normal gallbladder and common bile duct (CBD). Subsequently magnetic resonance cholangiopancreaticogram showed choledocholithiasis. Endoscopic retrograde cholangiopancreaticogram-with sphincterotomy and CBD stone extraction was performed. The patient progressively improved with antibiotic therapy Choledocholithiasis should be considered as a source of clostridium perfringens bacteremia especially in the setting of elevated liver enzymes with cholestatic pattern.展开更多
文摘本文以角叉菜胶（Car）25mg·kg<sup>-1</sup>诱导大鼠气囊滑膜炎模型为研究对象,观察了三七叶皂甙（PNGL）对Car诱导的气囊灌洗液中白细胞数及蛋白含量的影响,与此同时,还进一步观察了PNGL对灌洗液中PGE<sub>2</sub>含量及PLA<sub>2</sub>活性的影响。结果发现,Car致炎后气囊灌洗液中PLA<sub>2</sub>活性明显升高,于12h达峰值(248.5±41.8 vs 38.4±9.2U·ml<sup>-1</sup>,P【0.01);PGE<sub>2</sub>含量呈类似变化(1619±391 vs 397±41pg·mg<sup>-1</sup>,P【0.01);灌洗液中白细胞数及蛋白含量也显著升高(P均【0.
文摘A 67-years-old male presented with periumbilical abdominal pain, fever and jaundice. His anaerobic blood culture was positive for clostridium perfringens. Computed tomogram scan of the abdomen and abdominal ultrasound showed normal gallbladder and common bile duct (CBD). Subsequently magnetic resonance cholangiopancreaticogram showed choledocholithiasis. Endoscopic retrograde cholangiopancreaticogram-with sphincterotomy and CBD stone extraction was performed. The patient progressively improved with antibiotic therapy Choledocholithiasis should be considered as a source of clostridium perfringens bacteremia especially in the setting of elevated liver enzymes with cholestatic pattern.
