气溶酸盐治疗儿童哮喘的临床疗效观察

哮喘是当今世界上最常见的慢性疾患,我国儿童哮喘的患病率为0.5％～2％,个别地区则高达约5％。国外有报告哮喘的发病率以年5％的惊人速度增长,如此的发病率与增长率已使哮喘成为全世界公共卫生问题,成为各国关注的焦点。尽管目前在哮喘的防治中取得了一定的进展,但长期的药物治疗难免会有些不良影响,所以,寻找一种非药物疗法,以期减少药物的负荷及免除药物的副作用就显得特别重要。我们采用的气溶酸盐疗法在探索的过程中取得了较满意的效果,现报告如下:

MODELING THE EFFECTS OF ANTHROPOGENIC SULFATE IN CLIMATE CHANGE BY USING A REGIONAL CLIMATE MODEL

Effects of aerosol with focus on the direct climate effect of anthropogenic sulfate aerosol under 2×CO2 condition were investigated by introducing aerosol distribution into the latest version of RegCM2. Two experiments, first run (2×CO2 + 0 aerosol concentration) and second run (2×CO2 + aerosol distribution), were made for 5 years respectively. Preliminary analysis shows that the direct climate effect of aerosol might cause a decrease of surface air temperature. The decrease might be larger in winter and in South China. The regional-averaged monthly precipitation might also decrease in most of the months due to the effect. The annual mean change of precipitation might be a decrease in East and an increase in West China. But the changes of both temperature and precipitation simulated were much smaller as compared to the greenhouse effect.

Simulated Impacts of Sulfate and Nitrate Aerosol Formation on Surface-Layer Ozone Concentrations in China

The authors quantify the impacts of sulfate and nitrate aerosol formation on surface-layer 03 concentrations over China using the one-way nested-grid capa- bility of the global three-dimensional Goddard Earth Ob- serving System chemical transport model （GEOS-Chem）. Chemical reactions associated with sulfate formation are simulated to generally increase 03 concentrations in China. Over the North China Plain （NCP） and the Si- chuan Basin （SCB）, where simulated sulfate concentra- tions are the largest, ozone concentrations show maximum increases in spring by 1.8 ppbv （3.2%） in the NCP and by 2.6 ppbv （3.7%） in the SCB. On the contrary, nitrate formation is simulated to reduce 03 concentrations by up to 1.0 ppbv in eastern China, with the largest reduc- tions of 1.0 ppbv （1.4%） in summer over the NCE Ac- counting for the formation of both sulfate and nitrate, the surface-layer O3 concentrations over a large fraction of eastern China are simulated to increase in winter, spring, and autumn, dominated by the impact of sulfate forma- tion, but to decrease in summer because of the dominant contribution from nitrate formation.

Indirect Radiative and Climatic Effects of Sulfate and Organic Carbon Aerosols over East Asia Investigated by RIEMS

The indirect radiative and climatic effects of sulfate and organic carbon aerosols over East Asia were investigated using a Regional Integrated Environment Model System (RIEMS) with an empirical aerosol-cloud parameterization.The first indirect radiative forcing was negative and ranged from-9-0 W m-2 in the domain.The maximum cooling,up to-9 W m-2,occurred in the Chongqing District in winter,whereas the cooling areas were larger during summer than in winter.Organic carbon (OC) aerosols were more abundant in winter than in summer,whereas the sulfate concentration during summer was much higher than during winter.The concentrations of sulfate and OC were comparable in winter,and sulfate played a dominant role in determining indirect radiative forcing in summer,whereas in winter,both sulfate and OC were important.The regional mean indirect radiative forcings were-0.73 W m-2 and-0.41 W m-2 in summer and winter,respectively.The surface cooling caused by indirect effects was more obvious in winter than that in summer.The ground temperature decreased by ～1.2 K in most areas of eastern China in winter,whereas in summer,the temperature decreased (～-1.5 K) in some regions,such as the Yangtze River region,but increased (～0.9 K) in the areas between the Yellow and Yangtze Rivers.In winter,the precipitation decreased by 0-6 mm in most areas of eastern China,but in summer,alternating bands of increasing (up to 80 mm) and decreasing (～-80 mm) precipitation appeared in eastern China.

Transformation of Flue-Gas-Desulfurization Gypsum to α-Hemihydrated Gypsum in Salt Solution at Atmospheric Pressure

Direct phase transformation of flue gas desulfurization gypsum in hot salt solution at atmospheric pres-sure was investigated.The effects of temperature,salt species,salt concentration,solids content,pH and modifier were examined.The crystals obtained under different conditions and solubility of calcium sulfate in contact with solid gypsum were also determined.α-Calcium sulfate hemihydrate crystals of stubby columnar shape and regular pentahedral sides were obtained under the following conditions：salt concentration 20%-30%,operation tempera-ture 95-100 °C,solids mass content in the slurry 10%-30% and neutral pH.Thermodynamic analysis revealed that phase transformation of calcium sulfate dihydrate to α-calcium sulfate hemihydrate occurs because of the difference in solubilities between the two solid gypsum phases in this system.

Chemical characterization of submicron particles during typical air pollution episodes in spring over Beijing

Beijing experienced a long-lasting pollution episode in April 2012. Here, the authors characterize the sources and evolution processes of the pollution, with a focus on a haze and a dust episode that occurred during 15-30 April. All submicron aerosol species （PM1） showed substantial increases during the haze episode （HE）, with nitrate being the largest, contributing on average 32.2% of the non-refractory PM;（NR-PM1） mass （maximum： -42.0%）, which was different from other seasons. Secondary inorganic aerosol （SIA） species （55.1 ± 23.8 lag m-3; SIA = nitrate, ammonium, sulfate） played enhanced roles in the haze formation, accounting for 66.5% of the total NR-PM1 mass. In contrast to the HE, organics exhibited their highest levels （8.9 ± 5.4 lag m-3） among the NR-PM aerosol species during the dust episode, accounting for 64.0% on average. SIAs exhibited low concentration levels （4.6 ± 4.2 μg m-3） during the dust episode, contributing only 34.0% to the total NR-PM1 mass. This study suggests that air quality improvement strategies should be designed according to aerosol particle characteristics and formation mechanisms.

Influence of multi-chemical-component aerosols on the microphysics of warm clouds in North China

An adiabatic bin-sized cloud parcel model is developed by incorporating the multi-chemical-component (MCC) aerosol effects into the UWyo single-chemical-component (SCC) parcel model. The effects of MCC aerosols on the warm cloud microphysics in North China are investigated with the model. The simulations are initialized using the data on chemical components and number size distribution of aerosols measured during the IPAC (Influence of Pollution on Aerosols and Cloud Microphysics in North China) campaign in spring 2006. It is found that the MCC aerosols in North China increase the cloud droplet number concentration (CDNC) and decrease the effective radius more efficiently than pure ammonium-sulfate aerosols. It is also shown that the MCC aerosols in North China can narrow the cloud droplet spectra (CDS) by increasing CDNC in small size and decreasing CDNC in large size. Our results indicate that aerosol chemical components and their size distributions can influence the microphysics of warm clouds, and thus affect atmospheric radiation and precipitation. This should attract more attentions in weather and climate change research in the future.

Numerical simulation study of temperature change over East China in the past millennium

Despite many studies on reconstructing the climate changes over the last millennium in China,the cause of the China's climate change remains unclear.We used the UVic Earth System Climate Model(UVic Model),an Earth system model of intermediate complexity,to investigate the contributions of climate forcings(e.g.solar insolation variability,anomalous volcanic aerosols,greenhouse gas,solar orbital change,land cover changes,and anthropogenic sulfate aerosols) to surface air temperature over East China in the past millennium.The simulation of the UVic Model could reproduce the three main characteristic periods(e.g.the Medieval Warm Period(MWP),the Little Ice Age(LIA),and the 20th Century Warming Period(20CWP)) of the northern hemisphere and East China,which were consistent with the corresponding reconstructed air temperatures at century scales.The simulation result reflected that the air temperature anomalies of East China were larger than those of the global air temperature during the MWP and the first half of 20CWP and were lower than those during the LIA.The surface air temperature of East China over the past millennium has been divided into three periods in the MWP,four in the LIA,and one in the 20CWP.The MWP of East China was caused primarily by solar insolation and secondarily by volcanic aerosols.The variation of the LIA was dominated by the individual sizes of the contribution of solar insolation variability,greenhouse gas,and volcano aerosols.Greenhouse gas and volcano aerosols were the main forcings of the third and fourth periods of the LIA,respectively.We examined the nonlinear responses among the natural and anthropogenic forcings in terms of surface air temperature over East China.The nonlinear responses between the solar orbit change and anomalous volcano aerosols and those between the greenhouse gases and land cover change(or anthropogenic sulfate aerosols) all contributed approximately 0.2℃ by the end of 20th century.However,the output of the energy-moisture balance atmospheric model from UVic showed no obvious nonlinear responses between anthropogenic and natural forcings.The nonlinear responses among all the climate forcings(both anthropogenic and natural forcings) contributed to a temperature increase of approximately 0.27℃ at the end of the 20th century,accounting for approximately half of the warming during this period;the remainder was due to the climate forcings themselves.