甲状腺结节是一种常见的以颈部甲状腺肿大为主要特征的疾病,临床发现其与情绪的关系密切,随着现代社会生活压力的增加,甲状腺结节的发病率也逐年提升,影响人们的生活质量,因此应尽早防治。目前西医治疗甲状腺结节主要是定期随访观察、...甲状腺结节是一种常见的以颈部甲状腺肿大为主要特征的疾病,临床发现其与情绪的关系密切,随着现代社会生活压力的增加,甲状腺结节的发病率也逐年提升,影响人们的生活质量,因此应尽早防治。目前西医治疗甲状腺结节主要是定期随访观察、射频消融、手术和甲状腺激素类药物为主,不良反应较多。祖国医学对甲状腺结节认识广泛,认为其属中医瘿病范围,气滞、痰凝、血瘀是甲状腺结节的重要病机,治疗时运用疏肝理气,活血化瘀,化痰散结法,予以患者中药汤剂、针刺、外敷等治疗,在临床上具有改善甲状腺功能,缩小甲状腺结节体积,改善临床症状的作用。Thyroid nodule is a common disease mainly characterized by neck goiter, which is clinically found to be closely related to emotions. With the increase of life pressure in modern society, the incidence of thyroid nodule is also increasing year by year, affecting people’s quality of life, so it should be prevented and treated as soon as possible. At present, Western medicine treats thyroid nodules mainly by regular follow-up observation, radiofrequency ablation, surgery and thyroid hormone drugs, and there are more adverse reactions. The Chinese medicine has a wide understanding of thyroid nodule, which belongs to the scope of gall disease of Chinese medicine. Qi stagnation, spittoon and blood stasis are the important pathogenesis of thyroid nodule. In the treatment, the method of soothing liver and regulating qi, promoting blood circulation and removing blood stasis, resolving phlegm and dispersing knot are used to treat patients with traditional Chinese medicine decoction, acupuncture and external application, which has the effect of improving thyroid function, reducing the volume of thyroid nodule and improving clinical symptoms.展开更多
目的评价开郁苦泄法治疗气郁痰阻型新诊断超重2型糖尿病患者的临床疗效。方法研究纳入新诊断2型糖尿患者100例,随机分为治疗组和对照组各50例,在生活方式干预下,治疗组口服甘松降糖颗粒9 g/次,3次/日,对照组口服二甲双胍500 mg/次,3次/...目的评价开郁苦泄法治疗气郁痰阻型新诊断超重2型糖尿病患者的临床疗效。方法研究纳入新诊断2型糖尿患者100例,随机分为治疗组和对照组各50例,在生活方式干预下,治疗组口服甘松降糖颗粒9 g/次,3次/日,对照组口服二甲双胍500 mg/次,3次/日,共观察12周,记录两组血糖、HbA1c、HOMA指数及脂代谢指标等统计分析。结果(1)研究完成可评价样本83例,治疗组43例,对照组40例,治疗组和对照组HbA1c分别下降1.14%和1.34%,FBG降低1.93 mmol·L^(-1)和2.23 mmol·L^(-1),2 h BG降低5.72 mmol·L^(-1)和6.56 mmol·L^(-1),组内比较差异均有统计学意义(P<0.01),组间比较差异无统计学意义(P>0.05)。(2)胰岛素释放试验结果显示两组各时段血糖均较前明显下降(P<0.05),且1 h PG治疗组下降优于对照组(P<0.05),治疗组1 h INS升高优于对照组(P<0.05),两组3 h INS均较前降低(P<0.05),组间比较差异无统计学意义(P>0.05)。(3)两组治疗后体重、腰围、BMI下降均有统计学意义(P<0.01),治疗组TC和对照组LDL-C下降有统计学意义(P<0.05),组间比较差异均无统计学意义(P>0.05)。(4)两组HOMA-IR和ISI均明显改善(P<0.01),组间比较无差异(P>0.05),两组HOMA-β较治疗前变化无统计学意义(P>0.05),但组间比较治疗组改善优于对照组(P<0.01)。(5)两组证候疗效比较治疗组总有效率90.70%,对照组77.50%,治疗组明显优于对照组(P<0.01)。结论开郁苦泄法治疗新诊断超重2型糖尿病(气郁痰阻型)在控制血糖、减轻体重、改善胰岛素抵抗、调节血脂方面疗效与二甲双胍相当,并能显著改善患者中医证候。展开更多
文摘甲状腺结节是一种常见的以颈部甲状腺肿大为主要特征的疾病,临床发现其与情绪的关系密切,随着现代社会生活压力的增加,甲状腺结节的发病率也逐年提升,影响人们的生活质量,因此应尽早防治。目前西医治疗甲状腺结节主要是定期随访观察、射频消融、手术和甲状腺激素类药物为主,不良反应较多。祖国医学对甲状腺结节认识广泛,认为其属中医瘿病范围,气滞、痰凝、血瘀是甲状腺结节的重要病机,治疗时运用疏肝理气,活血化瘀,化痰散结法,予以患者中药汤剂、针刺、外敷等治疗,在临床上具有改善甲状腺功能,缩小甲状腺结节体积,改善临床症状的作用。Thyroid nodule is a common disease mainly characterized by neck goiter, which is clinically found to be closely related to emotions. With the increase of life pressure in modern society, the incidence of thyroid nodule is also increasing year by year, affecting people’s quality of life, so it should be prevented and treated as soon as possible. At present, Western medicine treats thyroid nodules mainly by regular follow-up observation, radiofrequency ablation, surgery and thyroid hormone drugs, and there are more adverse reactions. The Chinese medicine has a wide understanding of thyroid nodule, which belongs to the scope of gall disease of Chinese medicine. Qi stagnation, spittoon and blood stasis are the important pathogenesis of thyroid nodule. In the treatment, the method of soothing liver and regulating qi, promoting blood circulation and removing blood stasis, resolving phlegm and dispersing knot are used to treat patients with traditional Chinese medicine decoction, acupuncture and external application, which has the effect of improving thyroid function, reducing the volume of thyroid nodule and improving clinical symptoms.
文摘目的评价开郁苦泄法治疗气郁痰阻型新诊断超重2型糖尿病患者的临床疗效。方法研究纳入新诊断2型糖尿患者100例,随机分为治疗组和对照组各50例,在生活方式干预下,治疗组口服甘松降糖颗粒9 g/次,3次/日,对照组口服二甲双胍500 mg/次,3次/日,共观察12周,记录两组血糖、HbA1c、HOMA指数及脂代谢指标等统计分析。结果(1)研究完成可评价样本83例,治疗组43例,对照组40例,治疗组和对照组HbA1c分别下降1.14%和1.34%,FBG降低1.93 mmol·L^(-1)和2.23 mmol·L^(-1),2 h BG降低5.72 mmol·L^(-1)和6.56 mmol·L^(-1),组内比较差异均有统计学意义(P<0.01),组间比较差异无统计学意义(P>0.05)。(2)胰岛素释放试验结果显示两组各时段血糖均较前明显下降(P<0.05),且1 h PG治疗组下降优于对照组(P<0.05),治疗组1 h INS升高优于对照组(P<0.05),两组3 h INS均较前降低(P<0.05),组间比较差异无统计学意义(P>0.05)。(3)两组治疗后体重、腰围、BMI下降均有统计学意义(P<0.01),治疗组TC和对照组LDL-C下降有统计学意义(P<0.05),组间比较差异均无统计学意义(P>0.05)。(4)两组HOMA-IR和ISI均明显改善(P<0.01),组间比较无差异(P>0.05),两组HOMA-β较治疗前变化无统计学意义(P>0.05),但组间比较治疗组改善优于对照组(P<0.01)。(5)两组证候疗效比较治疗组总有效率90.70%,对照组77.50%,治疗组明显优于对照组(P<0.01)。结论开郁苦泄法治疗新诊断超重2型糖尿病(气郁痰阻型)在控制血糖、减轻体重、改善胰岛素抵抗、调节血脂方面疗效与二甲双胍相当,并能显著改善患者中医证候。
