N,N-Ditosyl-1,5-diazacycloheptan-3-one(2) and its derivatives(3b^3d) have been synthesized from 1,3-dichloro-2-propanol and N,N-ditosylethylenediamine via cyclization, oxidation and substitution. All the new compo...N,N-Ditosyl-1,5-diazacycloheptan-3-one(2) and its derivatives(3b^3d) have been synthesized from 1,3-dichloro-2-propanol and N,N-ditosylethylenediamine via cyclization, oxidation and substitution. All the new compounds(2 and 3a^3d) have been characterized by IR, 1H NMR, MS and elemental analysis. The reactions of all steps are carried out under moderate conditions with the overall yield 27%~30%.展开更多
文摘N,N-Ditosyl-1,5-diazacycloheptan-3-one(2) and its derivatives(3b^3d) have been synthesized from 1,3-dichloro-2-propanol and N,N-ditosylethylenediamine via cyclization, oxidation and substitution. All the new compounds(2 and 3a^3d) have been characterized by IR, 1H NMR, MS and elemental analysis. The reactions of all steps are carried out under moderate conditions with the overall yield 27%~30%.
