Studies on radiation level and radionuclide distribution in Yemen were studied. The samples were collected from eight locations： Ma＇rib, A1 Jawf, Sana＇a, Dhamar, Amran, Ibb, Al Bayda and Al Dalea. The purpose of th...Studies on radiation level and radionuclide distribution in Yemen were studied. The samples were collected from eight locations： Ma＇rib, A1 Jawf, Sana＇a, Dhamar, Amran, Ibb, Al Bayda and Al Dalea. The purpose of this study is to provide a baseline map of radioactivity background levels in the investigated area and this study will be used as reference information to assess any change in the radioactive background level due to geological processes. The highest values of 22~ and 2~l＇h concentrations （8797.2 and 24984.1 Bq.kg＂l, respectively） were observed at A1 Jawf, region, whereas the highest average value of 40K concentration was 1561.9 Bq.kg-1. The investigation of the geological maps of the area under study showed that the surface rock outcrops consist mainly of granites, diorite, granodiorite, gneisses, and schists. All these rock types arc known to be rich in radioactive materials, which are considered natural sources for gamma radiation. The low mdiological background characterizing some Yemeni rocks could be attributed to nature of these rocks which consist of lime stone （sands and gravels）. The absorbed dose rate in air was found to be in the range between 5.40 and 45.11 nGy.h-1 depending on the geological features, and radium equivalent activity concentration was found in the range between 29.57 and 71.85 Bq.kg-1. Also the representative extcmal hazard index values for the corresponding samples were also estinlated and given.展开更多
Objective: We aimed to study the transcription level of VEGF-C in human breast cancer tissue, and explore the correlations with the expression of C-erbB-2. Methods: The expression of VEGF-C mRNA in 51 cases of human b...Objective: We aimed to study the transcription level of VEGF-C in human breast cancer tissue, and explore the correlations with the expression of C-erbB-2. Methods: The expression of VEGF-C mRNA in 51 cases of human breast cancer was assessed by hybridization in situ. The expressions of C-erbB-2 was assessed by immunohistochemistry. Results: The positive rate of VEGF-C mRNA was 54.9% in 51 cases of breast cancer. The transcription level had correlation with tumor size and status of lymph nodes(P < 0.05). The expression of VEGF-C mRNA had a positive correlation with the expression of C-erbB-2(P < 0.05). Conclusion: The up-expression of VEGF-C has a significant correlation with the malignancy level and clinical stage of breast cancer. The combined detection of VEGF-C, C-erbB-2 may help to estimate the prognosis of patients with breast cancer and study on thetherapeutic implications.展开更多
文摘Studies on radiation level and radionuclide distribution in Yemen were studied. The samples were collected from eight locations： Ma＇rib, A1 Jawf, Sana＇a, Dhamar, Amran, Ibb, Al Bayda and Al Dalea. The purpose of this study is to provide a baseline map of radioactivity background levels in the investigated area and this study will be used as reference information to assess any change in the radioactive background level due to geological processes. The highest values of 22~ and 2~l＇h concentrations （8797.2 and 24984.1 Bq.kg＂l, respectively） were observed at A1 Jawf, region, whereas the highest average value of 40K concentration was 1561.9 Bq.kg-1. The investigation of the geological maps of the area under study showed that the surface rock outcrops consist mainly of granites, diorite, granodiorite, gneisses, and schists. All these rock types arc known to be rich in radioactive materials, which are considered natural sources for gamma radiation. The low mdiological background characterizing some Yemeni rocks could be attributed to nature of these rocks which consist of lime stone （sands and gravels）. The absorbed dose rate in air was found to be in the range between 5.40 and 45.11 nGy.h-1 depending on the geological features, and radium equivalent activity concentration was found in the range between 29.57 and 71.85 Bq.kg-1. Also the representative extcmal hazard index values for the corresponding samples were also estinlated and given.
基金Supported by grants from the Liaoning Province Science&Technology Development Funds(No.2012225019)Sub-topics of Major Drug Discovery Platform in the Twelfth-Five Year Research Program of China(No.2012ZX09303016-002)
文摘Objective: We aimed to study the transcription level of VEGF-C in human breast cancer tissue, and explore the correlations with the expression of C-erbB-2. Methods: The expression of VEGF-C mRNA in 51 cases of human breast cancer was assessed by hybridization in situ. The expressions of C-erbB-2 was assessed by immunohistochemistry. Results: The positive rate of VEGF-C mRNA was 54.9% in 51 cases of breast cancer. The transcription level had correlation with tumor size and status of lymph nodes(P < 0.05). The expression of VEGF-C mRNA had a positive correlation with the expression of C-erbB-2(P < 0.05). Conclusion: The up-expression of VEGF-C has a significant correlation with the malignancy level and clinical stage of breast cancer. The combined detection of VEGF-C, C-erbB-2 may help to estimate the prognosis of patients with breast cancer and study on thetherapeutic implications.
