Failure to tolerate prosthetic material can lead to a variety of clin ical fin dings. A 55-year-oldwoman had a total replacement of the right knee. Two wee ks later she developed pruritic skin lesions over the joint, ...Failure to tolerate prosthetic material can lead to a variety of clin ical fin dings. A 55-year-oldwoman had a total replacement of the right knee. Two wee ks later she developed pruritic skin lesions over the joint, as well as pain and impaired function. Allergic testing showed clinically relevant Type IV sensitiz ation to methylmethacrylate, as well as to various formulations of the bone ceme nt, including one with an added antibiotic. The symptom complex of pruritic skin lesions in the area of the prosthesis, pain and disability, as well as relevant Type IV sensitization justified replacing the prosthesis.展开更多
文摘Failure to tolerate prosthetic material can lead to a variety of clin ical fin dings. A 55-year-oldwoman had a total replacement of the right knee. Two wee ks later she developed pruritic skin lesions over the joint, as well as pain and impaired function. Allergic testing showed clinically relevant Type IV sensitiz ation to methylmethacrylate, as well as to various formulations of the bone ceme nt, including one with an added antibiotic. The symptom complex of pruritic skin lesions in the area of the prosthesis, pain and disability, as well as relevant Type IV sensitization justified replacing the prosthesis.
