The energy saving issue of chilled water system in an intelligent building is analyzed from the systematic point of view, and an optimum scheduling scheme which can save energy of the system facilities and satisfy the...The energy saving issue of chilled water system in an intelligent building is analyzed from the systematic point of view, and an optimum scheduling scheme which can save energy of the system facilities and satisfy the constraints of the real time cold loads and system running is also proposed. It can make the minimum cost of the system by optimizing the number of running chillers, running parameters and the distribution of real time loads of running chillers. The improved genetic algorithm is used in the optimum scheduling scheme. The computation results show that the building energy consumption can be decreased by about 10%.展开更多
The paper follows possible specification of a control algorithm of a WS （water management system） during floods using the procedures of AI （artificial intelligence）. The issue of minimizing negative impacts of flo...The paper follows possible specification of a control algorithm of a WS （water management system） during floods using the procedures of AI （artificial intelligence）. The issue of minimizing negative impacts of floods represents influencing and controlling a dynamic process of the system where the main regulation elements are water reservoirs. Control of water outflow from reservoirs is implicitly based on the used model （titled BW） based on FR （fuzzy regulation）. Specification of a control algorithm means dealing with the issue of preparing a knowledge base for the process of tuning fuzzy regulators based on an I/O （input/output） matrix obtained by optimization of the target behaviour of WS. Partial results can be compared with the regulation outputs when specialized tuning was used for the fuzzy regulator of the control algorithm. Basic approaches follow from the narrow relation on BW model use to simulate floods, without any connection to real water management system. A generally introduced model allows description of an outflow dynamic system with stochastic inputs using submodels of robust regression in the outflow module. The submodels are constructed on data of historical FS （flood situations）.展开更多
Endothelial cell dysfunction is a term which implies the dysregulation of normal endothelial cell functions,including impairment of the barrier functions,control of vascular tone,disturbance of proliferative and migra...Endothelial cell dysfunction is a term which implies the dysregulation of normal endothelial cell functions,including impairment of the barrier functions,control of vascular tone,disturbance of proliferative and migratory capacity of endothelial cells,as well as control of leukocyte trafficking.Endothelial dysfunction is an early step in vascular inflammatory diseases such as atherosclerosis,diabetic vascular complications,sepsis-induced or severe virus infection-induced organ injuries.The expressions of inflammatory cytokines and vascular adhesion molecules induced by various stimuli,such as modified lipids,smoking,advanced glycation end products and bacteria toxin,significantly contribute to the development of endothelial dysfunction.The transcriptional regulation of inflammatory cytokines and vascular adhesion molecules has been well-studied.However,the regulation of those gene expressions at post-transcriptional level is emerging.RNA-binding proteins have emerged as critical regulators of gene expression acting predominantly at the post-transcriptional level in microRNA-dependent or independent manners.This review summarizes the latest insights into the roles of RNA-binding proteins in controlling vascular endothelial cell functions and their contribution to the pathogenesis of vascular inflammatory diseases.展开更多
文摘The energy saving issue of chilled water system in an intelligent building is analyzed from the systematic point of view, and an optimum scheduling scheme which can save energy of the system facilities and satisfy the constraints of the real time cold loads and system running is also proposed. It can make the minimum cost of the system by optimizing the number of running chillers, running parameters and the distribution of real time loads of running chillers. The improved genetic algorithm is used in the optimum scheduling scheme. The computation results show that the building energy consumption can be decreased by about 10%.
文摘The paper follows possible specification of a control algorithm of a WS （water management system） during floods using the procedures of AI （artificial intelligence）. The issue of minimizing negative impacts of floods represents influencing and controlling a dynamic process of the system where the main regulation elements are water reservoirs. Control of water outflow from reservoirs is implicitly based on the used model （titled BW） based on FR （fuzzy regulation）. Specification of a control algorithm means dealing with the issue of preparing a knowledge base for the process of tuning fuzzy regulators based on an I/O （input/output） matrix obtained by optimization of the target behaviour of WS. Partial results can be compared with the regulation outputs when specialized tuning was used for the fuzzy regulator of the control algorithm. Basic approaches follow from the narrow relation on BW model use to simulate floods, without any connection to real water management system. A generally introduced model allows description of an outflow dynamic system with stochastic inputs using submodels of robust regression in the outflow module. The submodels are constructed on data of historical FS （flood situations）.
基金supported by the National Natural Science Foundation of China(91339113,81270202,81070095 to Xin HongBo)the National Basic Research Program of China(2013CB531103 to Xin HongBo)
文摘Endothelial cell dysfunction is a term which implies the dysregulation of normal endothelial cell functions,including impairment of the barrier functions,control of vascular tone,disturbance of proliferative and migratory capacity of endothelial cells,as well as control of leukocyte trafficking.Endothelial dysfunction is an early step in vascular inflammatory diseases such as atherosclerosis,diabetic vascular complications,sepsis-induced or severe virus infection-induced organ injuries.The expressions of inflammatory cytokines and vascular adhesion molecules induced by various stimuli,such as modified lipids,smoking,advanced glycation end products and bacteria toxin,significantly contribute to the development of endothelial dysfunction.The transcriptional regulation of inflammatory cytokines and vascular adhesion molecules has been well-studied.However,the regulation of those gene expressions at post-transcriptional level is emerging.RNA-binding proteins have emerged as critical regulators of gene expression acting predominantly at the post-transcriptional level in microRNA-dependent or independent manners.This review summarizes the latest insights into the roles of RNA-binding proteins in controlling vascular endothelial cell functions and their contribution to the pathogenesis of vascular inflammatory diseases.
