In this article different types of ultradeformable liposomes were designed and the properties of transdermal delivery were studied with sodium salicylate as model drug. These results showed that liposomes with stron...In this article different types of ultradeformable liposomes were designed and the properties of transdermal delivery were studied with sodium salicylate as model drug. These results showed that liposomes with strong hydrophilic surfactant added is a new type of penetration enhancer.展开更多
The effect of annual additions of composted sewage sludge (CS) and thermally dried sewage sludge (TS) at 80 t ha-1 on soil chemical properties was investigated for three years in a field experiment under semiarid cond...The effect of annual additions of composted sewage sludge (CS) and thermally dried sewage sludge (TS) at 80 t ha-1 on soil chemical properties was investigated for three years in a field experiment under semiarid conditions. Humic acids (HAs) isolated by conventional procedures from CS, TS, and unamended (SO) and sludge amended soils were analysed for elemental (C, H, N, S and O) and acidic functional groups (carboxylic and phenolic) and by ultraviolet-visible, Fourier transform infrared and fluorescence spectroscopies. With respect to CS, TS had similar pH and total P and K contents, larger dry matter, total organic C, total N and C/N ratio and smaller ash content and electrical conductivity. Amendment with both CS and TS induced a number of modifications in soil properties, including an increase of pH, electrical conductivity, total organic C, total N, and available P. The CS-HA had greater O, total acidity, carboxyl, and phenolic OH group contents and smaller C and H contents than TS-HA. The CS-HA and TS-HA had larger N and S contents, smaller C, O and acidic functional group contents, and lower aromatic polycondensation and humification degrees than SO-HA. Amended soil-HAs showed C, H, N and S contents larger than SO-HA, suggesting that sludge HAs were partially incorporated into soil HAs. These effects were more evident with increasing number of sludge applications.展开更多
Among the reactions catalyzed by zeolites there are some that exhibit high selectivity due to the spatial confinement effect of the zeolite framework.Tailoring the acidity,particularly the distribution and location of...Among the reactions catalyzed by zeolites there are some that exhibit high selectivity due to the spatial confinement effect of the zeolite framework.Tailoring the acidity,particularly the distribution and location of the Bronsted acid sites in the zeolite is effective for making it a better catalyst for these reactions.We prepared a series of H-mordenite(H-MOR) samples by varying the composition of the sol-gel,using different structure directing agents and post-treatment.NH3-TPD and IR characterization of adsorbed pyridine were employed to determine the amount of Bronsted acid sites in the 8-membered ring and 12-membered ring channels.It was shown that controlled synthesis was a promising approach to improve the concentration of Bronsted acid sites in MOR,even with a low Al content.Using an appropriate composition of Si and Al in the sol-gel favored a higher proportion of Bronsted acid sites in the 8-membered ring channels.HMI as a structure-direct agent gave an obvious enrichment of Bronsted acid sites in the 8-membered ring.Carbonylation of dimethyl ether was used as a probe reaction to examine the modification of the acid properties,especially the Bronsted acid sites in the 8-membered ring channels.There was a linear relationship between methyl acetate formation and the number of Bronsted acid sites in the 8-membered ring channels,demonstrating the successful modification of acid properties.Our results provide information for the rational design and modification of zeolites with spatial constraints.展开更多
The surface properties of PAN-based carbon fibers electrochemically treated in aqueous ammonium bicarbonate before and after treatment were characterized by X-ray photoelectron spectroscopy (XPS), atomic force microsc...The surface properties of PAN-based carbon fibers electrochemically treated in aqueous ammonium bicarbonate before and after treatment were characterized by X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM) and Dynamic Contact Angle Analysis (DCAA). The results of characterization indicated that the oxygen and nitrogen contents in carbon fiber surface were significantly increased by electrochemical treatment, and amide groups was introduced onto it, which was related with the electrolyte. The AFM photographs illustrated that the roughness of the fiber surface was also increased. The wettibality of the fibers was improved after treatment because the surface energy especially the polar part of it was increased.展开更多
In order to investigate the change of ecological characteristics due to the decrease of COD/SO_4^(2-) ratio during sulfate reduction, continuous-flew tests were conducted in an acidogenic sulfate-reducing reactor with...In order to investigate the change of ecological characteristics due to the decrease of COD/SO_4^(2-) ratio during sulfate reduction, continuous-flew tests were conducted in an acidogenic sulfate-reducing reactor with molasses wastewater as sole organic carbon source and sodium snlfate as electron acceptor, and the change of pH value, oxidation reduction potential (ORP), volatile fat acids (VFAs), alkalinity (ALK) and the predominant populations with COD/SO_4^(2-) ratio decreasing from 4.2 to 2.0 were investigated. The experimental results demonstrated that, with decreasing COD/SO_4^(2-) ratio, ORP and ALK increased, pH value decreased, and the proportion of acetic acid in terminal products decreased significantly, and a stable -type microbial community with high COD/SO_4^(2-) ratio was converted into a sub -stable -type one with low COD/SO_4^(2-) ratio.展开更多
Lanthanum titanate (La2/3 TiO3) powders were synthesized by hydrothermal method based on the reaction of TiO2, La(NO3)3 and KOH at 160℃ for 24 h followed by the treatment of acidification. The microstructure, mor...Lanthanum titanate (La2/3 TiO3) powders were synthesized by hydrothermal method based on the reaction of TiO2, La(NO3)3 and KOH at 160℃ for 24 h followed by the treatment of acidification. The microstructure, morphology and dielectric properties were investigated by using X-ray diffraction, scanning electron microscope, transmission electron microscope and impedance method. The results show that the La2/3TiO3 particles consist of nearly homogenous and lamellar grains. The particles can be sintered into porous ceramics above 1150℃. The dielectric properties of La2/3 TiO3 show that both the dielectric constant and the dielectric loss tangent decrease with the increase of frequency.展开更多
In order to investigate the difference of phtotocatalytic properties of TiO2 samples prepared in different pH conditions, TiO2 nanopartieles were prepared in acidic medium and basic medium by a hydrothermal process, r...In order to investigate the difference of phtotocatalytic properties of TiO2 samples prepared in different pH conditions, TiO2 nanopartieles were prepared in acidic medium and basic medium by a hydrothermal process, respectively. The samples were characterized using XRD, TEM, BET, XPS, surface photovoltage spectroscopy (SPS) and field-induced surface photovohage spectroscopy (FISPS). Effects of temperature and pH in the hydrothermal process on particle sizes, specific surface areas, and photoeatalytic properties of the TiO2 nanoerystalline were investigated. The experimental results indicate that the photocatalysis activity of TiO2 nanoparticles prepared in basic medium ( B-TiO2 ) is superior to that in acidic medium ( A-TiO2 ), which is ascribed to the difference of surface state between A-TiO2 and B-TiO2.展开更多
Antioxidant activity of the peptides derived from proteins of defatted cottonseed kernels and cotton ground oil-cake by their enzymatic hydrolysis with acidic (Asp. niger) and neutral proteinases (Bac. amyloliquefa...Antioxidant activity of the peptides derived from proteins of defatted cottonseed kernels and cotton ground oil-cake by their enzymatic hydrolysis with acidic (Asp. niger) and neutral proteinases (Bac. amyloliquefaciens) was studied. Antioxidant activity of the derived peptides depended on the used proteins and enzymes. The peptides derived by using of neutral proteinase possessed higher antioxidant activity, in comparison with the peptides derived by acidic proteinases.展开更多
OBJECTIVE To observe the effect of all-trans retinoic acid (ATRA) on inducing human glioma MO59K cells differentiation and further explore the underlying molecular mechanisms.METHODS The expression of glial fibrilla...OBJECTIVE To observe the effect of all-trans retinoic acid (ATRA) on inducing human glioma MO59K cells differentiation and further explore the underlying molecular mechanisms.METHODS The expression of glial fibrillary acidic protein (GFAP) was detected by immunocytochemistry staining. The mRNA levels of GFAP, retinoid X receptor α(RXRα), p21 were examined by semi-quantitative RT-PCR analysis. Luciferase activity assay was performed in the COS-7, MO59K cells to measure p21 promoter transcription activity.RESULTS ATRA could significantly enhance the expression and mRNA level of GFAP by immunostaining and RT-PCR (P〈0.05). Simultaneously, the mRNA levels of RXRα and p21 were remarkably increased in dose-dependent manner by RT-PCR (P〈0.05). Furthermore, luciferase assay confirmed that ATRA and RXRα could transactivate p21 promoter in COS-7 and glioma cells (P〈0.05).CONCLUSION ATRA can induce differentiation of human glioma cells. The RXRα and p21 were activated during ATRAinduced differentiation process. This effect may be caused by directly RXRα-induced p21 gene transactivation. Our findings provide novel evidence for the future studies to explore the molecular mechanism of transcriptional regulation for glioma cell differentiation and cellular therapeutic approaches for glioblastoma.展开更多
The effect of cement on physiochemical properties of three types of soils i.e garden soil, agricultural soil and roadside soil was investigated. The ordinary Portland cement was used. The amount of cement added to soi...The effect of cement on physiochemical properties of three types of soils i.e garden soil, agricultural soil and roadside soil was investigated. The ordinary Portland cement was used. The amount of cement added to soil samples, as dry mass percentage was 20%. The results of analysis showed that the addition of cement is capable of bringing about changes in physiochemical properties of soil. The electrical conductivity and organic matter content in three soils get decreased by the addition of cement. While the pH, bulk density and water holding capacity of soils after the addition of cement gets increased. The soil found most suitable to be treated with cement was roadside soil. It was concluded that cement can be used to change the physiochemical properties of soil and this technique has great utility in improving the quality of problematic soils.展开更多
文摘In this article different types of ultradeformable liposomes were designed and the properties of transdermal delivery were studied with sodium salicylate as model drug. These results showed that liposomes with strong hydrophilic surfactant added is a new type of penetration enhancer.
文摘The effect of annual additions of composted sewage sludge (CS) and thermally dried sewage sludge (TS) at 80 t ha-1 on soil chemical properties was investigated for three years in a field experiment under semiarid conditions. Humic acids (HAs) isolated by conventional procedures from CS, TS, and unamended (SO) and sludge amended soils were analysed for elemental (C, H, N, S and O) and acidic functional groups (carboxylic and phenolic) and by ultraviolet-visible, Fourier transform infrared and fluorescence spectroscopies. With respect to CS, TS had similar pH and total P and K contents, larger dry matter, total organic C, total N and C/N ratio and smaller ash content and electrical conductivity. Amendment with both CS and TS induced a number of modifications in soil properties, including an increase of pH, electrical conductivity, total organic C, total N, and available P. The CS-HA had greater O, total acidity, carboxyl, and phenolic OH group contents and smaller C and H contents than TS-HA. The CS-HA and TS-HA had larger N and S contents, smaller C, O and acidic functional group contents, and lower aromatic polycondensation and humification degrees than SO-HA. Amended soil-HAs showed C, H, N and S contents larger than SO-HA, suggesting that sludge HAs were partially incorporated into soil HAs. These effects were more evident with increasing number of sludge applications.
基金supported by the National Natural Science Foundation of China(21325626,21406120)the Postdoctoral Science Foundation of China(2014M560181,2015T80214)~~
文摘Among the reactions catalyzed by zeolites there are some that exhibit high selectivity due to the spatial confinement effect of the zeolite framework.Tailoring the acidity,particularly the distribution and location of the Bronsted acid sites in the zeolite is effective for making it a better catalyst for these reactions.We prepared a series of H-mordenite(H-MOR) samples by varying the composition of the sol-gel,using different structure directing agents and post-treatment.NH3-TPD and IR characterization of adsorbed pyridine were employed to determine the amount of Bronsted acid sites in the 8-membered ring and 12-membered ring channels.It was shown that controlled synthesis was a promising approach to improve the concentration of Bronsted acid sites in MOR,even with a low Al content.Using an appropriate composition of Si and Al in the sol-gel favored a higher proportion of Bronsted acid sites in the 8-membered ring channels.HMI as a structure-direct agent gave an obvious enrichment of Bronsted acid sites in the 8-membered ring.Carbonylation of dimethyl ether was used as a probe reaction to examine the modification of the acid properties,especially the Bronsted acid sites in the 8-membered ring channels.There was a linear relationship between methyl acetate formation and the number of Bronsted acid sites in the 8-membered ring channels,demonstrating the successful modification of acid properties.Our results provide information for the rational design and modification of zeolites with spatial constraints.
基金Sponsored by the Scientific Research Foundation of Harbin Institute of Technology(Grant No. HIT. 2003.57)
文摘The surface properties of PAN-based carbon fibers electrochemically treated in aqueous ammonium bicarbonate before and after treatment were characterized by X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM) and Dynamic Contact Angle Analysis (DCAA). The results of characterization indicated that the oxygen and nitrogen contents in carbon fiber surface were significantly increased by electrochemical treatment, and amide groups was introduced onto it, which was related with the electrolyte. The AFM photographs illustrated that the roughness of the fiber surface was also increased. The wettibality of the fibers was improved after treatment because the surface energy especially the polar part of it was increased.
基金Sponsored by the National Natural Science Foundation of China(Grant No. 50208006)the Scientific Research Foundation of Harbin Institute of Technology(Grant No. HIT. 2001.51)
文摘In order to investigate the change of ecological characteristics due to the decrease of COD/SO_4^(2-) ratio during sulfate reduction, continuous-flew tests were conducted in an acidogenic sulfate-reducing reactor with molasses wastewater as sole organic carbon source and sodium snlfate as electron acceptor, and the change of pH value, oxidation reduction potential (ORP), volatile fat acids (VFAs), alkalinity (ALK) and the predominant populations with COD/SO_4^(2-) ratio decreasing from 4.2 to 2.0 were investigated. The experimental results demonstrated that, with decreasing COD/SO_4^(2-) ratio, ORP and ALK increased, pH value decreased, and the proportion of acetic acid in terminal products decreased significantly, and a stable -type microbial community with high COD/SO_4^(2-) ratio was converted into a sub -stable -type one with low COD/SO_4^(2-) ratio.
文摘Lanthanum titanate (La2/3 TiO3) powders were synthesized by hydrothermal method based on the reaction of TiO2, La(NO3)3 and KOH at 160℃ for 24 h followed by the treatment of acidification. The microstructure, morphology and dielectric properties were investigated by using X-ray diffraction, scanning electron microscope, transmission electron microscope and impedance method. The results show that the La2/3TiO3 particles consist of nearly homogenous and lamellar grains. The particles can be sintered into porous ceramics above 1150℃. The dielectric properties of La2/3 TiO3 show that both the dielectric constant and the dielectric loss tangent decrease with the increase of frequency.
基金Sponsored by the Key Program Projects of National Natural Science Foundation of China(Grant No. 20431030)the Foundation for Excellent Youth of Heilongjiang University (2005)+2 种基金the Foundation for Youth Science and Technology Innovation Talents of Harbin of China(Grant No.2006RFQXS096)the Key Item Projects of Educational Department of Heilongjiang Province of China(Grant No.1152Z002)Heilongjiang Postdoctoral Funds for Scientific Research Initiation(Grant No.LBH-Q07111)
文摘In order to investigate the difference of phtotocatalytic properties of TiO2 samples prepared in different pH conditions, TiO2 nanopartieles were prepared in acidic medium and basic medium by a hydrothermal process, respectively. The samples were characterized using XRD, TEM, BET, XPS, surface photovoltage spectroscopy (SPS) and field-induced surface photovohage spectroscopy (FISPS). Effects of temperature and pH in the hydrothermal process on particle sizes, specific surface areas, and photoeatalytic properties of the TiO2 nanoerystalline were investigated. The experimental results indicate that the photocatalysis activity of TiO2 nanoparticles prepared in basic medium ( B-TiO2 ) is superior to that in acidic medium ( A-TiO2 ), which is ascribed to the difference of surface state between A-TiO2 and B-TiO2.
文摘Antioxidant activity of the peptides derived from proteins of defatted cottonseed kernels and cotton ground oil-cake by their enzymatic hydrolysis with acidic (Asp. niger) and neutral proteinases (Bac. amyloliquefaciens) was studied. Antioxidant activity of the derived peptides depended on the used proteins and enzymes. The peptides derived by using of neutral proteinase possessed higher antioxidant activity, in comparison with the peptides derived by acidic proteinases.
基金the National Natural Science Foundation of China,Shandong Province Natural Science Foundation,Tianjin Natural Science Foundation
文摘OBJECTIVE To observe the effect of all-trans retinoic acid (ATRA) on inducing human glioma MO59K cells differentiation and further explore the underlying molecular mechanisms.METHODS The expression of glial fibrillary acidic protein (GFAP) was detected by immunocytochemistry staining. The mRNA levels of GFAP, retinoid X receptor α(RXRα), p21 were examined by semi-quantitative RT-PCR analysis. Luciferase activity assay was performed in the COS-7, MO59K cells to measure p21 promoter transcription activity.RESULTS ATRA could significantly enhance the expression and mRNA level of GFAP by immunostaining and RT-PCR (P〈0.05). Simultaneously, the mRNA levels of RXRα and p21 were remarkably increased in dose-dependent manner by RT-PCR (P〈0.05). Furthermore, luciferase assay confirmed that ATRA and RXRα could transactivate p21 promoter in COS-7 and glioma cells (P〈0.05).CONCLUSION ATRA can induce differentiation of human glioma cells. The RXRα and p21 were activated during ATRAinduced differentiation process. This effect may be caused by directly RXRα-induced p21 gene transactivation. Our findings provide novel evidence for the future studies to explore the molecular mechanism of transcriptional regulation for glioma cell differentiation and cellular therapeutic approaches for glioblastoma.
文摘The effect of cement on physiochemical properties of three types of soils i.e garden soil, agricultural soil and roadside soil was investigated. The ordinary Portland cement was used. The amount of cement added to soil samples, as dry mass percentage was 20%. The results of analysis showed that the addition of cement is capable of bringing about changes in physiochemical properties of soil. The electrical conductivity and organic matter content in three soils get decreased by the addition of cement. While the pH, bulk density and water holding capacity of soils after the addition of cement gets increased. The soil found most suitable to be treated with cement was roadside soil. It was concluded that cement can be used to change the physiochemical properties of soil and this technique has great utility in improving the quality of problematic soils.