Pediatric cardiac surgery with cardiopulmonary bypass (CPB)-is frequently associated with neurologic deficits. We describe the postoperative EEG changes, assess their possible causes, and evaluate their relevance to n...Pediatric cardiac surgery with cardiopulmonary bypass (CPB)-is frequently associated with neurologic deficits. We describe the postoperative EEG changes, assess their possible causes, and evaluate their relevance to neurologic outcome. Thirty-one children and five neonates with congenital heart disease were included. EEG recording started after intubation and continued until 22-96 h after CPB. In addition to conventional analysis, spectral analysis was performed for occipital and frontal electrodes, and differences between pre-and postoperative delta power (delta-δP) were calculated. Maximum values of occipital delta-δP that occurred within 48 h after CPB were correlated with clinical variables and with perioperative markers of oxidative stress and inflammation. Occipital delta-δP correlated with frontal delta-δP, and maximum delta-δP correlated with conventional rating. Distinct rise of δP was detected in 18 of 21 children without any acute or long-term neurologic deficits but only in five of 10 children with temporary or permanent neurologic deficits. Furthermore, maximally registered delta-δP was inversely associated with duration of CPB and postoperative ventilation. Maximal delta-δP was also inversely associated with the loss of plasma ascorbate (as an index of oxidative stress) and plasma levels of IL-6 and IL-8. Slow wave activity frequently occurs within 48 h after CPB. However, our data do not support the notion that EEG slowing is associated with adverse neurologic outcome. This is supported by the fact that EEG slowing was associated with less oxido-inflammatory stress.展开更多
利用NCEP/NCAR再分析资料,通过合成分析、诊断分析等方法研究了淮河流域夏季降水异常年份的大尺度环流场,并且分析了造成这种环流背景的可能原因。结果表明:西风急流在多雨年和少雨年作为波导的作用没有变化,但多雨年西风急流的位置比...利用NCEP/NCAR再分析资料,通过合成分析、诊断分析等方法研究了淮河流域夏季降水异常年份的大尺度环流场,并且分析了造成这种环流背景的可能原因。结果表明:西风急流在多雨年和少雨年作为波导的作用没有变化,但多雨年西风急流的位置比少雨年偏东。在中高纬地区,多雨和少雨年200 h Pa沿西风急流的定常Rossby波列结构有明显的不同。在多雨年,有一条明显的沿西风急流传播的Rossby波列结构,波源位于西欧和中亚,波汇位于里海和我国淮河流域地区,日本以东的西北太平洋也是明显的波源区;在少雨年,西欧和中亚的波源地区的波活动明显减弱,原来位于淮河流域的波汇区南压到长江以南,西北太平洋上的波活动也明显减弱。这种波列结构的不同可能是造成淮河流域夏季降水异常的一个重要原因。展开更多
文摘Pediatric cardiac surgery with cardiopulmonary bypass (CPB)-is frequently associated with neurologic deficits. We describe the postoperative EEG changes, assess their possible causes, and evaluate their relevance to neurologic outcome. Thirty-one children and five neonates with congenital heart disease were included. EEG recording started after intubation and continued until 22-96 h after CPB. In addition to conventional analysis, spectral analysis was performed for occipital and frontal electrodes, and differences between pre-and postoperative delta power (delta-δP) were calculated. Maximum values of occipital delta-δP that occurred within 48 h after CPB were correlated with clinical variables and with perioperative markers of oxidative stress and inflammation. Occipital delta-δP correlated with frontal delta-δP, and maximum delta-δP correlated with conventional rating. Distinct rise of δP was detected in 18 of 21 children without any acute or long-term neurologic deficits but only in five of 10 children with temporary or permanent neurologic deficits. Furthermore, maximally registered delta-δP was inversely associated with duration of CPB and postoperative ventilation. Maximal delta-δP was also inversely associated with the loss of plasma ascorbate (as an index of oxidative stress) and plasma levels of IL-6 and IL-8. Slow wave activity frequently occurs within 48 h after CPB. However, our data do not support the notion that EEG slowing is associated with adverse neurologic outcome. This is supported by the fact that EEG slowing was associated with less oxido-inflammatory stress.
文摘利用NCEP/NCAR再分析资料,通过合成分析、诊断分析等方法研究了淮河流域夏季降水异常年份的大尺度环流场,并且分析了造成这种环流背景的可能原因。结果表明:西风急流在多雨年和少雨年作为波导的作用没有变化,但多雨年西风急流的位置比少雨年偏东。在中高纬地区,多雨和少雨年200 h Pa沿西风急流的定常Rossby波列结构有明显的不同。在多雨年,有一条明显的沿西风急流传播的Rossby波列结构,波源位于西欧和中亚,波汇位于里海和我国淮河流域地区,日本以东的西北太平洋也是明显的波源区;在少雨年,西欧和中亚的波源地区的波活动明显减弱,原来位于淮河流域的波汇区南压到长江以南,西北太平洋上的波活动也明显减弱。这种波列结构的不同可能是造成淮河流域夏季降水异常的一个重要原因。
