Mutual information （MI）-based image registration is effective in registering medical images, but it is computationally expensive. This paper accelerates MI-based image registration by dividing computation of mutual ...Mutual information （MI）-based image registration is effective in registering medical images, but it is computationally expensive. This paper accelerates MI-based image registration by dividing computation of mutual information into spatial transformation and histogram-based calculation, and performing 3D spatial transformation and trilinear interpolation on graphic processing unit （GPU）. The 3D floating image is downloaded to GPU as flat 3D texture, and then fetched and interpolated for each new voxel location in fragment shader. The transformed resuits are rendered to textures by using frame buffer object （FBO） extension, and then read to the main memory used for the remaining computation on CPU. Experimental results show that GPU-accelerated method can achieve speedup about an order of magnitude with better registration result compared with the software implementation on a single-core CPU.展开更多
[Objective] Based on the cotton variety high yielding potential, fiber quality traits, disease resistance, and early maturity characters, a cultivar registration index model was developed to simplify the tedious calcu...[Objective] Based on the cotton variety high yielding potential, fiber quality traits, disease resistance, and early maturity characters, a cultivar registration index model was developed to simplify the tedious calculation process in national cotton registration procedure, and thus to enhance the practical application of cultivar regis- tration index in cotton breeding ancl cotton recommending. [Method] By means of correlation analysis, partial correlation analysis and path analysis methods, the cor- relation of cotton main properties and their effects on cultivar registration index were explored using the dataset of national cotton regional trials in Yangtze River Valley during 1996-2013. The cultivar registration index model was constructed with step- wise regression statistical technique to ascertain the quantitative relationship of main characters with cultivar registration index, and the regional cotton trial dataset in 2013 was used to validate the model. [Result] Several characters with larger deter- minants to cultivar registration index were screened out,ie. lint yield increase ratio, pro-frost yield ratio, verticillium wilt index, fiber strength, fusarium wilt index and mi- cronaire value. The cultivar registration index model defined the functional relation- ship of cultivar registration index with the selected main characters, among which lint yield increase ratio, fiber strength and micronaire value contributed most to culti- var registration index. The model validation with regional cotton trials in 2013 indi- cated the root mean square error, RMSE was only 2.77, and the variation coeffi- cient was 6.77%, which confirmed the model prediction effect was quite perfect. [Conclusion] The developed cultivar registration index model was reliable enough to simulate the complicated scoring system in cultivar registration procedure, also sim- plified cotton registration process, and enhanced the practicability of the cultivar reg- istration index.展开更多
Premature ovarian insufficiency（POI） affects seriously physical and mental health of the patients. Studies show that acupuncture may be promising in treating POI. yet evidence is insufficient. International patient ...Premature ovarian insufficiency（POI） affects seriously physical and mental health of the patients. Studies show that acupuncture may be promising in treating POI. yet evidence is insufficient. International patient registry, one form of observational study, is designed for evaluating effectiveness and safety of acupuncture in real-world clinical settings. We will face a series of opportunities and challenges. The opportunities are as follows：（1） Interdisciplinary cooperation can improve the effect of acupuncture for POI.（2） The protocol for acupuncture to treat POI has room for improvement.（3） The patient registry study can make up the shortcomings of randomized controlled trials.（4） The patient registry study can collect real-world data and explore responses of different populations to acupuncture and can be the foundation for the successive studies. International patient registry may face technological, ethical and financial challenges, while the established International Patient Registry Platform of Acupuncture-Moxibustion（www.amreg.org：8082/v3） is actively responding to these challenges. Till now there have been more than 300 patients of POI enrolled on this platform.展开更多
基金Supported by National High Technology Research and Development Program("863"Program)of China(No.863-306-ZD13-03-06)
文摘Mutual information （MI）-based image registration is effective in registering medical images, but it is computationally expensive. This paper accelerates MI-based image registration by dividing computation of mutual information into spatial transformation and histogram-based calculation, and performing 3D spatial transformation and trilinear interpolation on graphic processing unit （GPU）. The 3D floating image is downloaded to GPU as flat 3D texture, and then fetched and interpolated for each new voxel location in fragment shader. The transformed resuits are rendered to textures by using frame buffer object （FBO） extension, and then read to the main memory used for the remaining computation on CPU. Experimental results show that GPU-accelerated method can achieve speedup about an order of magnitude with better registration result compared with the software implementation on a single-core CPU.
基金Supported by National Major Projects for the GMO Cultivation of New Varieties in China(2012ZX08013015)
文摘[Objective] Based on the cotton variety high yielding potential, fiber quality traits, disease resistance, and early maturity characters, a cultivar registration index model was developed to simplify the tedious calculation process in national cotton registration procedure, and thus to enhance the practical application of cultivar regis- tration index in cotton breeding ancl cotton recommending. [Method] By means of correlation analysis, partial correlation analysis and path analysis methods, the cor- relation of cotton main properties and their effects on cultivar registration index were explored using the dataset of national cotton regional trials in Yangtze River Valley during 1996-2013. The cultivar registration index model was constructed with step- wise regression statistical technique to ascertain the quantitative relationship of main characters with cultivar registration index, and the regional cotton trial dataset in 2013 was used to validate the model. [Result] Several characters with larger deter- minants to cultivar registration index were screened out,ie. lint yield increase ratio, pro-frost yield ratio, verticillium wilt index, fiber strength, fusarium wilt index and mi- cronaire value. The cultivar registration index model defined the functional relation- ship of cultivar registration index with the selected main characters, among which lint yield increase ratio, fiber strength and micronaire value contributed most to culti- var registration index. The model validation with regional cotton trials in 2013 indi- cated the root mean square error, RMSE was only 2.77, and the variation coeffi- cient was 6.77%, which confirmed the model prediction effect was quite perfect. [Conclusion] The developed cultivar registration index model was reliable enough to simulate the complicated scoring system in cultivar registration procedure, also sim- plified cotton registration process, and enhanced the practicability of the cultivar reg- istration index.
基金Supported by Ministry of Science and Technology of the People's Republic of China through the Twelfth Five-Year National Science and Technology Pillar Program(2012BAI24B02)~~
文摘Premature ovarian insufficiency（POI） affects seriously physical and mental health of the patients. Studies show that acupuncture may be promising in treating POI. yet evidence is insufficient. International patient registry, one form of observational study, is designed for evaluating effectiveness and safety of acupuncture in real-world clinical settings. We will face a series of opportunities and challenges. The opportunities are as follows：（1） Interdisciplinary cooperation can improve the effect of acupuncture for POI.（2） The protocol for acupuncture to treat POI has room for improvement.（3） The patient registry study can make up the shortcomings of randomized controlled trials.（4） The patient registry study can collect real-world data and explore responses of different populations to acupuncture and can be the foundation for the successive studies. International patient registry may face technological, ethical and financial challenges, while the established International Patient Registry Platform of Acupuncture-Moxibustion（www.amreg.org：8082/v3） is actively responding to these challenges. Till now there have been more than 300 patients of POI enrolled on this platform.
