传感器的医学应用

本文简述了生物分子元件同换能器相结合的医用传感器在临床上的广泛用途。

Development of a Thermal Fogger-specific Sedimentation Stabilizer

In order to solve the drifting away of thermal fog droplets during thermal spraying and the incompatibility between fog droplet carrier and conventional com- mercial agro-chemicals, the fog droplet carrier, surfactant, condensation nucleus ma- terial and antifreeze, dispersant, thickener and defoamer were screened and assem- bled to develop a thermal fog sedimentation stabilizer in this study, thereby provid- ing technical support for application and promotion of thermal spraying technology in pest and disease control in crops.

公布了利用重组植物生产海藻糖的成果

美国Calgene公司将微生物的使葡萄糖转换戍海藻糖的基因导入植物,生产海藻糖获得成功。在荷兰阿姆斯特丹召开的植物分子生物学会议上发表了这项成果。6月中旬与种苗企业D.J.van der Have公司合作利用重组植物生产在香料、色素、质地等稳定剂方面需要的海藻糖,有微生物发酵生产和利用重组植物生产海藻糖的技术。

医学应用传感器的发展研究

阐述了生物分子元件同换能器相结合的医用传感器在临床上的广范用途。

传感器的医学应用

简述了生物分子元件同换能器相结合的医用传感器在临床上的广泛用途。

Cellular and molecular mechanisms of intestinal fibrosis

Fibrosis is a chronic and progressive process characterized by an excessive accumulation of extracellular matrix (ECM) leading to stiffening and/or scarring of the involved tissue. Intestinal fibrosis may develop in several different enteropathies, including inflammatory bowel disease. It develops through complex cell, extracellular matrix, cytokine and growth factor interactions. Distinct cell types are involved in intestinal fibrosis, such as resident mesenchymal cells (fibroblasts, myofibroblasts and smooth muscle cells) but also ECM-producing cells derived from epithelial and endothelial cells (through a process termed epithelialand endothelial-mesenchymal transition), stellate cells, pericytes, local or bone marrow-derived stem cells. The most important soluble factors that regulate the activation of these cells include cytokines, chemokines, growth factors, components of the renin-angiotensin system, angiogenic factors, peroxisome proliferator-activated receptors, mammalian target of rapamycin, and products of oxidative stress. It soon becomes clear that although inflammation is responsible for triggering the onset of the fibrotic proc-ess, it only plays a minor role in the progression of this condition, as fibrosis may advance in a self-perpetuating fashion. Definition of the cellular and molecular mechanisms involved in intestinal fibrosis may provide the key to developing new therapeutic approaches.

Modeling of mass transfer characteristics of bubble column reactor with surfactant present

Danckwert’s method was used to determine the specific interfacial area, a, and the individual mass transfer coefficient, kL, during absorption of CO2 in a bubble column with an anionic surfactant in the carbonate-bicarbonate buffer solution and NaAsO2 as catalyst, the presence of which decreases the specific interfacial area and the individual mass transfer coefficient. The specific interfacial area and the individual mass transfer coefficient increase with increasing su- perficial gas velocity. The specific interfacial area decreases whereas the individual mass transfer coefficient increases with increasing temperature. The results of experiments were used to determine the dependence of a, kL, and kLa on the surface tension, the temperature of the absorption phase, and the superficial velocity of the gas. The calculated results from the correlation were found to be within 10% deviation from the actual experimental results.

Moro orange juice prevents fatty liver in mice

AIM:To establish if the juice of Moro,an anthocyaninrich orange,may improve liver damage in mice with diet-induced obesity.METHODS:Eight-week-old mice were fed a high-fat diet(HFD) and were administrated water or Moro juice for 12 wk.Liver morphology,gene expression of lipid transcription factors,and metabolic enzymes were assessed.RESULTS:Mice fed HFD displayed increased body weight,insulin resistance and dyslipidemia.Moro juice administration limited body weight gain,enhanced insulin sensitivity,and decreased serum triglycerides and total cholesterol.Mice fed HFD showed liver steatosis associated with ballooning.Dietary Moro juice markedly improved liver steatosis by inducing the expression of peroxisome proliferator-activated receptor-α and its target gene acylCoA-oxidase,a key enzyme of lipid oxidation.Consistently,Moro juice consumption suppressed the expression of liver X receptor-α and its target gene fatty acid synthase,and restored liver glycerol-3-phosphate acyltransferase 1 activity.CONCLUSION:Moro juice counteracts liver steatogenesis in mice with diet-induced obesity and thus may represent a promising dietary option for the prevention of fatty liver.

Significance of humoral neopterin in clinical diagnostics and prognosis

Neopterin is bioactive substance released by the activated monocyte/macrophage, and an early and sensitive marker used for reflection of cellular immune activation status induced by the lymphocyte macrophage system. Observation of neopterin levels is conducive to the diagnosis and prognosis of various diseases. This article reviews the existing evidence that neopterin has an important role in cardiovascular risk, infectious diseases, malignancy, autoimmune diseases and transplantaiton.

Out of Absurdity On the Ending of Catch-22

As one of the first and most original creations of literary postmodernism, published in the year 1961, Catch-22＇s （1961） position in American literature remains secure. Yet its ending has been held as unconvincing ever since its publication. Taking the overall structure, tone, and the theme of the novel into consideration, this paper aims to prove the credibility of this controversial part. It consists of five sections apart from an introduction and a conclusion. Section One provides general information on the life and works of Joseph Heller. Section Two traces the impact of existentialism and the generation of black humor to clarify the literary position of Catch-22. Section Three brings out the disputative opinions on the ending part. Sections Four and Five, try to prove Yossarian＇s final desertion a natural and convincing ending from different perspectives： Section Four analyses how Yossarian gains an entropic vision of the cosmos; section Five studies his existential vision of physical life and searches for the immediate factors that propel Yossarian＇s desertion. Section five also explains the ending＇s change in tone and structure. The conclusion summarizes the paper and points out the social significance of the novel.

The Research of the Influential Factors of Wearing Comfort of Functional Underwear

Along with the rich material life, the change of the diet structure, people＇s shape also began to change.With performance m females is the body fat＇s increasing, the shape is not beautiful, therefore, body sculpting underwear has become the first choice for women to pursue beauty.To the requirement of sculpting body underwear is also becoming higher and higher for women.Comfortable and fashion is the sign of measuring a sculpting body underwear quality. This paper introduces the development history of sculpting body underwear, sculpting body underwear comfort evaluation index.And from the three aspects of the human body, clothing, environment do research to sculpting body underwear about the influence factors of wearing comfort.lt provides the certain reference value for consumers to purchase the sculpting body underwear and for enterprise to product sculpting body underwear.

In vitro Antimicrobial Activity and Phytochemical Screening of Local Plants

Antimicrobial activity of extracts of local plants was evaluated, with two strain i.e E. coil and S. aurri （gram positive and gram negative） microorganisms. The in vitro anti bacterial activity was performed by agar disc diffusion method. The most active antibacterial plants were S. trifiliatus and A. mexicana. The significant antibacterial activity of active extracts was compared with the standered, antimicrobics, streptomycin （10 μg/disc）. The results obtained in the present study suggest that S. trifoliatus and A. mexicana can be used in treating diseases caused by the test organism.

Effects of dichloroacetate on the activation of the mitochondrial pathway in C6 cells in vitro

Mitochondria are increasingly recognized as important targets for tumor treatment because of their central roles in apoptotic pathways and cellular metabolism. Dichloroacetate （DCA）, a low molecular weight mitochondria-targeting agent, exhibits potential therapeutic effects for tumors. Based on the effects of DCA on tumor cellular metabolism, we carried out this study to investigate the anti-tumor activity of DCA in C6 glioma cells in vitro. The results showed that DCA was able to increase the activity of pyruvate dehydrogenase （PDH）, induce the production of reactive oxygen species （ROS） and reduce the mitochondrial membrane potential （MMP） in C6 ceils in vitro （P〈0.05 or 0.01）, indicating that the anti-tumor effects of DCA in C6 cells could be through the activation of the mitochondrial pathway. In conclusion, mitochondria could be a viable therapeutic target for the treatment of glioma.

Collective motion of bacteria and their dynamic assembly behavior

In recent years, active matter systems have attracted considerable attentions due to their complex dynamic behaviors in physical and material science. In particular, microorganism systems have served as model systems for observing dynamic assembly and collective motility of active particles and significant progresses have been made on in-depth understanding of how high density bacteria colony behaves in the non-equilibrium state. In this mini-review, we mainly focus on the collective motion of bacteria and their dynamic assembly from four aspects： （1） the general phenomenon and biological mechanism of bacterial collective motion; （2） the common experimental techniques for studying bacterial motility; （3） some active systems on exploring bacterial collective behavior, which include both non-restricted free suspensions and those in relative confined geometric space; （4） the phenomenological and descriptive statistical methods and physical models on the underlying laws that lead to large-scale coordinate patterns in multicellular systems. This review aims to give a general picture of the collective motion in bacterial active matter systems experimentally and theoretically in order to reflect the interplays between individuals among populations in motion. It is expected that the general regulation rules related to the boundary effects in the complex systems and materials can be elucidated to some extent.