流感病毒相关性脑病(influenza-associated encephalopathy, IAE)是指在流感病毒的急性感染期出现的中枢神经系统功能障碍的一种临床综合征,主要发生在儿童,部分类型病死率及长期神经系统后遗症发生率较高。IAE的发病机制尚不完全清楚,...流感病毒相关性脑病(influenza-associated encephalopathy, IAE)是指在流感病毒的急性感染期出现的中枢神经系统功能障碍的一种临床综合征,主要发生在儿童,部分类型病死率及长期神经系统后遗症发生率较高。IAE的发病机制尚不完全清楚,也因此缺乏统一的治疗方案,IAE的临床诊疗面临严峻挑战。本文综述IAE可能的发病机制及治疗进展,为临床诊治IAE提供参考。Influenza-associated encephalopathy (IAE) is a clinical syndrome of central nervous system dysfunction that occurs during the acute infection period of influenza virus. It mainly occurs in children and some types have high mortality rate and long-term neurological sequelae. The pathogenesis of IAE is still not fully understood, and there is a lack of standard treatment strategy, which makes the management of IAE a challenge. This article reviews the possible pathogenesis and progress in treatment of IAE, aiming to provide reference for clinical diagnosis and treatment of IAE.展开更多
文摘流感病毒相关性脑病(influenza-associated encephalopathy, IAE)是指在流感病毒的急性感染期出现的中枢神经系统功能障碍的一种临床综合征,主要发生在儿童,部分类型病死率及长期神经系统后遗症发生率较高。IAE的发病机制尚不完全清楚,也因此缺乏统一的治疗方案,IAE的临床诊疗面临严峻挑战。本文综述IAE可能的发病机制及治疗进展,为临床诊治IAE提供参考。Influenza-associated encephalopathy (IAE) is a clinical syndrome of central nervous system dysfunction that occurs during the acute infection period of influenza virus. It mainly occurs in children and some types have high mortality rate and long-term neurological sequelae. The pathogenesis of IAE is still not fully understood, and there is a lack of standard treatment strategy, which makes the management of IAE a challenge. This article reviews the possible pathogenesis and progress in treatment of IAE, aiming to provide reference for clinical diagnosis and treatment of IAE.
